Clinical Trial Search

Primary: Patients With Clinical Signs of Respiratory Depression or Sub Clinical Respiratory Depressions Measured by Capnography and Pulse Oximetry. — 22; 21 Participants

Primary: Patients Satisfaction — 6.33; 6.45 score on a scale

Primary: Level of Sedation Throughout the Entire Procedure — 22; 9; 10; 1 participants

Primary: Decreased Minute Ventilation — 0.736; 0.764 percentage of baseline — p=<0.0001

Primary: Number of Participants With Sub-clinical Respiratory Depression and Clinical Events Associated With Respiratory Depression During the Sedation Procedure — 11; 12…

Primary: Amplitudes (in Micro Volts) of Acoustic Event Related Potentials (Time-locked Amplitudes in the Electroencephalogram 100 Milliseconds After the Acoustic Stimulus…

Primary: Pain Felt During the Procedure — 0.29; 0.30 score on a scale

Primary: Respiratory Depression (Sub-clinical and Clinical Signs) — 0.4; 0.6 percentage of participants

Primary: Leiden Surgical Rating Scale — 4.8; 4.8 score on a scale — p=0.94

Primary: Proportion of Patients Who Have a Clinically Acceptable Surgical Conditions — 0.89; 1 Proportion of patients

Primary: Correlation of Sedation Indices Performance Across Anesthesia Range — 0.8314 Pearson r

Primary: Number of Intervention — 1.9; 7.5 Number of intervention — p=0.05

Primary: Total Average Anesthetic — 1.1890; 1.2906 percentage of sevoflurane

Primary: Number of Participants That Need an Airway Intervention. — 0; 5 participants

Primary: Peak Airway Pressures — 25.5; 28.3; 28; 30 cm H2O — p=0.01

Primary: BIS Signal Variability Using the Measured Standard Deviation During the Maintenance Phase of Anesthesia — 7.6; 7.8 units on a scale — p=0.651

Primary: Respiratory Events Requiring Intervention — 17; 2 Participants

Primary: Percentage of Subjects Ready for Discharge in Each Group at 30 Minutes Post Procedure — 26; 44 Participants

Primary: Respiratory Disturbance Index — 57.52; 21.32 events per hour

Primary: Change in Serum Catecholamines — 87; 106 mcg/ml — p=0.940

Primary: Change in Cognitive Function — 47.5; 40.4; 44.7; 37.8 units on a scale — p=0.001

Primary: Task Completing Time Change Between Sedation and Baseline Measured by 9-hole Peg Test — 27.8; 19.1; 54.3; 21.4 seconds — p=<0.01

Primary: Number of Participants Requiring Adjustment in Propofol Dosing — 16; 2 Participants

Primary: Change of Cytokine — 35.9; 12.2; 31.4; 22.9 pg/ml

Primary: Modified Observers Assessment of Alertness/Sedation (MOAA/S) Score 2 Minutes From Beginning of Maintenance Period — 0; 0; 0; 1 Participants

Primary: Blood Oxygen Level Dependent (BOLD) Response to Visual Stimuli — 0.56; 0.51 percentage of BOLD signal — p=0.62

Primary: The Correlation Between the Paired BIS Value Categories and Clinical Sedation Scores — 0.917; 0.874 correlation coefficient

Primary: Classic Score>1 — 66; 54 participants

Primary: Total Score of the Quality of Recovery-40 Questionnaire (QoR-40) — 169.3; 169.5 score on a scale

Primary: Change From Baseline to Peak Salivary Cortisol Level — 2.9; 4.3; 3.3 Number (ratio of peak to baseline)