N/A N=35 Neural Bases of Cognitive Rehabilitation for Brain Injury
Brain Injury
Primary: Change From Baseline on a Composite Measure (Z-score) of Attention, Working Memory, and Executive Functions — 0.26; .01 Change to Z (composite) score
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=61 Neurocognitive Benefits of a Weight Management Program
Overweight and Obesity
Primary: Blood Oxygen Level-dependent (BOLD) Response to High-calorie Foods Cues Minus Neutral Objects in Left Anterior Cingulate Cortex — -0.05; -0.16 percent BOLD signal change
N/A N=110 Cognitive Rehabilitation for PD
Parkinson's Disease
Primary: Wechsler Adult Intelligence Scale-IV (WAIS-IV) Matrix Reasoning Test Total Scaled Score — 0.22; 0.42 score on a scale — p=0.6662
Phase 2 N=20 Effect of Cenicriviroc on HIV Neurocognitive Impairment
AIDS Dementia Complex · HIV-1-Associated Cognitive Motor Complex · Human Immunodeficiency Virus
Primary: Change From Baseline to Week 24 in Global Neuropsychological Performance — .24 units on a scale — p=0.0079
Phase 1 N=52 Behavioral and Neuroimaging Changes After Cognitive Rehab in Traumatic Brain Injuries (TBI) and Mild Cognitive Impairment (MCI)
Mild Cognitive Impairment · Alzheimer's Disease · Traumatic Brain Injury
Primary: Memory Test Accuracy on Trained Stimuli — 53.9; 37.6; 48.9; 37.3 Percent correct
Phase 2 N=73 Cognitive Stimulation
Substance Use Disorders
Primary: Working Memory — 0.86; 0.04 digits recalled
N/A N=95 Cognitive Dysfunction In Parkinson's
Parkinson's
Primary: Differences in Error Rates on the NBack Task Between Real and Sham Stimulation Trials — -0.79; -0.1 incorrect responses
N/A N=72 Treatment to Enhance Cognition in Bipolar Disorder
Bipolar Disorder · Psychosis
Primary: MATRICS Consensus Cognitive Battery (MCCB) — 45.2; 45.5; 47.7; 49.3 T-scores
N/A N=18 Brain Markers of Improvements in Cognitive Functioning
TBI (Traumatic Brain Injury) · Brain Injuries · Stress
Primary: Composite Score of Attention and Executive Functioning From a Neurocognitive Test Battery — 0.18; -0.06 units on a scale
N/A N=60 Evaluation of Cognitive State Using Neurosteer EEG System
Cognitive Decline
Primary: Correlation Between Cognition Level Changes as Evaluated by Current Clinical Tools (i.e. MMSE) and Brain Activity Features Extracted Using the Neurosteer Technology…
N/A N=40 CogT BEEM Study (a tDCS Study)
Mild Cognitive Impairment · Neuropsychiatric Syndrome
Primary: Change of C3 Activation (NPS-shared Neural Circuit Measure — -0.15; 0.01 change of arbitrary unit LPG activation — p=<0.05
N/A N=69 Cognitive Training for Patients With Schizophrenia
Schizophrenia · Schizoaffective Disorder · Other Primary Psychotic Disorders
Primary: UCSD Performance-based Skills Assessment Total Score (Measures Functional Capacity) — 82.7; 84.4 units on a scale
N/A N=10 Transcranial Direct Current Stimulation (tDCS)
Brain Fog
Primary: Perceived Ease of Use After 4 Weeks of Daily tDCS Use (TAM Score) — 30.5 units on a scale
N/A N=93 Neuroplasticity in TBI and Schizophrenia
Schizophrenia · Traumatic Brain Injury
Primary: Mismatch Negativity (MMN) Amplitudes in Microvolts — -0.59; -1.19; -0.41; -0.65 microvolts
N/A N=107 Cognitive Training and Neuroplasticity in Mild Cognitive Impairment
Mild Cognitive Impairment · Memory Disorders · Memory Impairment
Primary: Change in the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) — -0.89; 0.55 score
N/A N=6 Cognitive Rehab for Parkinson's
Parkinson's Disease · Mild Cognitive Impairment
Primary: Change in NIH Sponsored Executive Abilities: Measures and Instruments for Neurobehavioral Evaluation and Research (NIH-EXAMINER) Executive Composite Score — 0.34; -.42…
N/A N=59 Cognitive Rehabilitation in Schizophrenia
Cognitive Impairment · Schizophrenia
Primary: Wisconsin Card Sort Percent Perseverative Errors (Standard Score) — 87.54; 87.88; 91.80 standard score units — p=<.97
N/A N=77 Evaluation of Cognitive State in Seniors Using Neurosteer EEG System
Cognitive Decline
Primary: Correlation Between Cognition Level Changes as Evaluated by Current Clinical Tools (i.e. MMSE, MoCA) and Brain Activity Features Extracted Using the Neurosteer…
N/A N=23 Optimizing Cognitive, Environmental, and Neuromotor Stimulation in Traumatic Brain Injury
Traumatic Brain Injury · Dementia Alzheimers · Military Activity
Primary: Change in Executive Functioning as Assessed by the Trail Making Test — -9.2; 24.7 change in seconds — p=.323
N/A N=107 Promoting Adaptive Neuroplasticity in Mild Cognitive Impairment
Mild Cognitive Impairment · Alzheimer's Disease
Primary: Face-name Memory Test Performance — -.28; -.01; -1.29; -1.76 pairs correctly recalled/recognized
N/A N=49 Cognitive Dysfunction in Parkinson's Disease
Parkinson's Disease
Primary: Change in Magnetoencephalography (MEG) Connectivity Measures
N/A N=250 Prevalence and Predictors of Neurocognitive Impairment Among HIV-infected Patients
HIV Infections · Memory
Primary: The Prevalence of Neurocognitive Deficits Among HIV-positive Patients as Defined by the Global Deficit Score Based on the Neuropsychological Testing Battery and to…
Phase 2 N=113 Nutraceutical Effects on Long-Term Memory
Aging
Primary: Delay Eyeblink Conditioning — 52.32; 56.88 percentage of conditioned responses
N/A N=100 Optimizing Cognitive Remediation
Schizophrenia · Stress Disorders, Post-Traumatic · Generalized Anxiety Disorder
Primary: MATRICS Consensus Cognitive Battery Global Composite T-score (MCCB-C) — 40.59 T-Score — p=0.078
N/A N=30 Cognitive Training in Parkinson's Disease
Parkinson Disease
Primary: Change in Quality of Life in Neurological Disorders Cognitive Function Version 2 (Neuro-QoL CF v2) T-scores at 6 Weeks — 49.9; 49.1; 50; 45.9 T-score — p=0.015
N/A N=167 Cognitive Training in Parkinson Study
Parkinson Disease · Impaired Cognition · Alteration in Cognition
Primary: Accuracy on the Tower of London Task — 81.2; 82.3; 88.1; 84.0 percentage of correct responses
N/A N=80 Evaluation of Cognitive State in Senior Subjects Using Neurosteer EEG System
Mild Cognitive Impairment
Primary: Correlation Between Cognition Level Changes as Evaluated by Current Clinical Tools (i.e. MMSE) and Brain Activity Features Extracted Using the Neurosteer Technology…
N/A N=200 Cerebral Oximetry and Neurocognitive Functions in Cardiosurgical Patients
Coronary Artery Disease · Postoperative Cognitive Dysfunction · Neurological Impairment
Primary: Difference in Incidence of Cognitive Impairment Between Groups. Change Between Preoperative and Postoperative Cognitive Function Was Assessed by Performing Standardized…
N/A N=38 Using Teleneuropsychology to Optimize Cognition in Healthy Aging: the Web-based Breakfast Game
Healthy Aging
Primary: Changes in the Breakfast Game Performance: Number of Tables Set Score — 1.61; 1.43 score on a scale (change)
N/A N=60 Neurophysiological Targets for Cognitive Training in Schizophrenia
Schizophrenia
Primary: Visual Target Detection (P300 Event-related Potential Amplitude) Change — 2.20; -0.72 microvolts (uV) — p=<0.05