Phase 2 N=80 Speech Entrainment for Aphasia Recovery
Aphasia · Aphasia Non Fluent · Stroke
Primary: Average Verbs Per Minute (VPM) Change From Baseline — 0.3; 0.62; -0.26; 0.52 verbs per minute
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=14 Treating Intention In Aphasia: Neuroplastic Substrates
Aphasia · Cerebrovascular Accident
Primary: Lateralization of Frontal Lobe (and Posterior Perisylvian) Activity During Word Production — -0.2802; -0.1832 laterality index — p=<.05
N/A N=28 Phonomotor Treatment of Word Retrieval Deficits in Individuals With Aphasia
Aphasia
Primary: Speech Production — 5.27; 5.28 % change score of untrained real words
N/A N=3 Transmagnetic Stimulation Pilot in Primary Progressive Aphasia
Primary Progressive Aphasia
Primary: Connectivity Measures of the Left TGd, 55b, and STV Parcellations at Baseline and Post-treatment — -.06; .03; -.01 correlation
N/A N=10 TMS for the Treatment of Primary Progressive Aphasia
Logopenic Variant Primary Progressive Aphasia · Non-fluent Variant Primary Progressive Aphasia · Semantic Variant Primary Progressive Aphasia
Primary: Changes in Language as Measured Through the Boston Naming Test (BNT) — 1.8; 2.5; 0.063; 0.5 Items
N/A N=58 Speech Therapy for Aphasia: Comparing Two Treatments
Stroke
Primary: Spoken Word Production (Confrontation Naming) — 53.01; 50.37 percent correct
N/A N=18 Determining Learning Ability in People With Aphasia
Aphasia
Primary: SRT Observational Learning Ability — -0.03 Cohen's d
N/A N=8 Rehabilitating and Decelerating Language Loss in Primary Progressive Aphasia With tDCS Plus Language Therapy
Primary Progressive Aphasia · PPA
Primary: Change in Accuracy of Naming Trained Verbs (0 to 15, Higher Scores Reflect Better Naming Abilities) as Assessed by Object and Action Naming Battery (OANB) — 2.3; 2.05…
N/A N=37 tDCS Intervention in Primary Progressive Aphasia
Primary Progressive Aphasia · MCI · FTD
Primary: Absolute Percent Change in Written Naming (Trained Items) — 39.4; 28.4; 33.1; 20.0 absolute percent change
N/A N=16 Transcranial Direct Current Stimulation for Primary Progressive Aphasia
Primary Progressive Aphasia
Primary: Aphasia Severity (WAB-AQ): Effects of Active tDCS (Baseline vs. 0 Weeks Immediately Following Stimulation) — 2.68; .87; 1.98; 2.25 score on a scale — p=0.14
N/A N=18 Treating Primary Progressive Aphasia (PPA) Using tDCS
Primary Progressive Aphasia
Primary: Western Aphasia Battery Aphasia Quotient (WAB-AQ) — 74.4; 76.5; 72.5; 76.0 scores on a scale — p=<.05
N/A N=23 Improving Aphasia Using Electrical Brain Stimulation
Stroke · Aphasia
Primary: Language Specific Attention Treatment Probe — 56; 47; 64; 52 Percent
Phase 1 N=25 Transcranial Magnetic Stimulation to Improve Speech in Aphasia
Aphasia · Cerebrovascular Stroke
Primary: Picture Naming — 10.3; 12.57; 12.1; 11.14 number of pictures — p=<0.028
Phase 3 N=36 Augmenting Language Therapy for Aphasia: Levodopa
Nonfluent Aphasia · Stroke
Primary: Language Quotient (LQ) on the Western Aphasia Battery — 3.16; 2.59 units on a scale
N/A N=16 Word Retrieval in the Wild in People With Post-Stroke Aphasia
Aphasia, Acquired
Primary: Change in Protocol Compliance — 67.35; 86.98 Percent response/n scheduled prompts — p=0.021
N/A N=10 TMS in Aphasia Recovery
Aphasia
Primary: Boston Naming Test — 10.3; 37.7 percent change from baseline
N/A N=12 Effects of Navigated Repetitive Transcranial Magnetic Stimulation According to Post-stroke Aphasia Types
To Healthy Volunteer · Virtual Lesions for Aphasia
Primary: The Change of Reaction Time Between Before and After Stimulation in Each Session (MTG, STG, Sham) — 110.65; -14.25; 25.29 msec
Phase 2 N=41 Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia
Aphasia
Primary: Change in WAB-AQ — 3.0; 2.8 score on a scale — p=<.05
N/A N=11 Stepped Care for Aphasia
Aphasia · Stroke
Primary: Change in the Depression Score on Hospital Anxiety and Depression Scale at Post-Intervention — 2.2 units on a scale — p=< .05
N/A N=20 Evaluation of Intensive Language Therapy
Parkinson's Disease
Primary: Velocity in Gait — 1.2; 1.2; 1.2; .8 meter per second — p=.05
N/A N=4 A Novel Treatment for Aphasia and Apraxia of Speech : Measurement of Outcomes
Apraxia of Speech · Aphasia
Primary: Change in Language Content Production for Treated Stimuli: Effect Sizes (Magnitude of Change From Baseline to Follow-up) — 13.38 units on a scale
N/A N=16 Effects of rTMS on Brain Activation in Aphasia
Aphasia, Acquired
Primary: Change in Philadelphia Naming Test (PNT) Performance — 122.125; 130.875; 132.5; 142.125 Score on a scale
N/A N=28 Post-Stroke Aphasia and Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment Study
Aphasia · Stroke
Primary: Aphasia Testing as Evaluated by the Boston Naming Test (BNT) - Baseline — 33.43; 18.29; 28.57; 41.00 units on a scale
N/A N=10 Speech Hero Home Therapy for Aphasia
Broca Aphasia
Primary: Number of Participants That Used the Device for at Least Ten Hours Over the Course of Four Weeks — 7 Participants
Phase 2 N=74 Brain Stimulation and Aphasia Treatment
Aphasia
Primary: The Philadelphia Naming Test (PNT) Plus the Naming 80 (a Portion of the Trained Items). — 13.9; 8.2 PNT and Naming 80 score
N/A N=9 Exercise as an Adjuvant to Aphasia Therapy
Aphasia
Primary: Change in Picture Naming Abilities as Measured by Tau U Effect Size Weighted Means — 0.83; 0.75; 0.88; 0.77 Tau U effect size weighted mean — p=< 0.001
N/A N=25 Transcranial Direct Current Stimulation (tDCS) and Intensive Therapy in Aphasia
Aphasia
Primary: Change in Controlled Oral Word Fluency — 3.1 number of words
N/A N=17 Assessing an Animal-Assisted Treatment Program for Adults With Aphasia: The Persons With Aphasia Training Dogs Program
Aphasia
Primary: Assessment of Living With Aphasia (ALA, Kagan et al., 2010) — 2.67; 2.33; 2.68; 2.43 units on a scale
N/A N=12 Low Frequency Subthalamic Nucleus Deep Brain Stimulation to Improve Verbal Fluency
Parkinson Disease
Primary: Delis-Kaplan Executive Function System Verbal Fluency — 12.75; 13.25; 13.58; 13.83 Words per minute
N/A N=75 Investigating the Effects of Rhythm and Entrainment on Fluency in People With Aphasia
Aphasia · Apraxia of Speech
Primary: Percent Syllables Correct — 99.22; 64.26; 99.46; 52.71 percentage — p=0.077