Clinical Trial Search

Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline

Primary: Change Form Baseline in WOMAC A Pain Subscale — -11.14; -11.82 cm — p=<0.025

Primary: Change of External Knee Adduction Moment as Assessed by Visual Motion Analysis System — 0.50 Nm/kg

Primary: Osteoarthritis Structural Changes Assessed by Quantitative Magnetic Resonance Imaging With and Without Neuropathic Pain — 14; 7; 5; 1 participants

Primary: The Lysholm Knee Score — 82.2; 83.4 units on a scale

Primary: Differences in Decision Conflict Scale With ASK vs Usual Care — 25.1; 26.0 Score on a scale

Primary: T1rho Relaxation Times in the Medial Femoral Condyle at Baseline — 53.48 ms

Primary: WOMAC Functional Status - Difference From Baseline — 20.9; 18.5 Score — p=0.26

Primary: Sum of Change in Brief Arthritis Stiffness Scale (BASS) Scores Over the 4-day Treatment Period — -12.6; -13.6; -11.7; -2.3 Scores on a scale

Primary: Change in Hyaluronate Concentration — 0.29568 mg/ml

Primary: Medial Condylar Separation With Brace — 0.60 mm

Primary: Number of Participants With Viable Specimens for Genetic Analysis — 14 participants

Primary: Number of Participants Experiencing One or More Treatment-Emergent Adverse Event — 28; 33 Participants — p=>0.9

Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared

Primary: Treatment Adherence — 24; 18 Participants

Primary: Change in 6-minute Walk Test — 22; 49 meters

Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC Score); Change From Baseline at 4 Months — 27.1; 33.3; 28.9; 26.7 units on a scale

Primary: Change in Basic Lower Limb Function (Late Life Function Index) Late Life Function and Disability Instrument — 3.3; -1.0; 3.1; 0.8 units on a scale

Primary: Change in Minimum Joint Space Width in the Medial Compartment of the Tibiofemoral Joint of the Signal Knee After 1 Year of Treatment — -0.1361; -0.0442; -0.2261; -0.2000…

Primary: Western Ontario and McMasters Universities Osteoarthritis Index (WOMAC) — 48.4; 48.4; 43.5; 41.2 units on a scale — p=0.158

Primary: Change From Baseline in WOMAC VA3.1 Pain Subscale Score at Month 6 — -23.6; -14.1 mm — p=0.141

Primary: Change From Baseline to Week 17 and From Baseline to Week 21 in Pain as Measured by Numerical Rating Scale — -2.1; -1.8; -2.2; -1.5 units on a scale — p=0.495

Primary: KOOS4 - Change From Baseline — 24.4; 25.3 units on a scale — p=<0.05

Primary: Pain When Walking On A Flat Surface — 0; 1; 8; 4 Participants

Primary: Change in International Knee Documentation Committee (IKDC) Subjective Knee Form Score — 22.2; 20.6 units on a scale

Primary: WOMET Score — 57.5; 99.4; 37.0; 63.9 units on a scale

Primary: Change From Baseline in the International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Score at 1 Year — 23.3; 9.9 scores on a scale — p=<0.01

Primary: Change at 6 Months From Baseline in First Peak Knee Adduction Moment (KAM): (6 Month Value - Baseline) — -0.19 %Bw*Ht

Primary: Infrapatellar Fat Pad Volume in MRI — 25154.96; 29202.39 mm^3

Primary: Knee Flexion Moment Impulse — 0.54; 0.50 Ratio — p=0.293