Clinical Trial Search

Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline

Primary: Change From Baseline to Week 17 and From Baseline to Week 21 in Pain as Measured by Numerical Rating Scale — -2.1; -1.8; -2.2; -1.5 units on a scale — p=0.495

Primary: Assessment of Pain Using the Visual Analog Scale — 48.7; 62.6; 50.8; 27.1 score on a scale

Primary: Change of External Knee Adduction Moment as Assessed by Visual Motion Analysis System — 0.50 Nm/kg

Primary: Differences in Decision Conflict Scale With ASK vs Usual Care — 25.1; 26.0 Score on a scale

Primary: Medial Condylar Separation With Brace — 0.60 mm

Primary: Gait Knee Adduction Moment — 3.14; 2.39 percent body weight (N)*height (m)

Primary: Change From Baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Domain Score at Week 2 — -3.64; -3.15 Units on a scale — p=0.39

Primary: Change in International Knee Documentation Committee (IKDC) Subjective Knee Form Score — 22.2; 20.6 units on a scale

Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) — -4.85; 0.26; -3.97; -2.53 units on a scale — p=0.0003

Primary: Number of Participants With Viable Specimens for Genetic Analysis — 14 participants

Primary: Total WOMAC Score — 51.64285714; 52.47619048; 39.60714286; 40.38095238 score on a scale

Primary: Change From Baseline in WOMAC VA3.1 Pain Subscale Score at Month 6 — -23.6; -14.1 mm — p=0.141

Primary: T1rho Relaxation Times in the Medial Femoral Condyle at Baseline — 53.48 ms

Primary: Pain When Walking On A Flat Surface — 0; 1; 8; 4 Participants

Primary: Change in Knee Extensor Torque — 130.1 Nm

Primary: Percentage of Participants Who Reported Adequate vs. Inadequate Pain Relief at Baseline — 46.2; 53.8 Percentage of Participants

Primary: Change Form Baseline in WOMAC A Pain Subscale — -11.14; -11.82 cm — p=<0.025

Primary: 30 Second Chair Standing Test — 9.5 stands

Primary: Change in Lower Extremity Function — 10.6; 7.6; -6.4 Change in scores on a scale

Primary: WOMAC Total in Week 15 — 11.6; 54.4 score on a scale — p=<0.001

Primary: WOMAC Functional Status - Difference From Baseline — 20.9; 18.5 Score — p=0.26

Primary: Narcotic Consumption — 15.87; 13.67 morphine equivalents, mg

Primary: Change in KOOS4 From Baseline (Knee Injury and Osteoarthritis Outcome Score) — 16.0; 32.5 units on a scale

Primary: Quadriceps Muscle Force — 1.27; 1.37; 0.79; 0.66 Nm/kg — p=0.07

Primary: Change in Knee Injury and Osteoarthritis Outcome Score (KOOS) — 3.3; 8.9; 4.6; 9.7 score on a scale — p=<0.05

Primary: Change of the Total WOMAC Score (WOMAC-T) — -624.12; -444.82; -605.61; -426.31 score on a scale — p=0.00030

Primary: Knee Injury and Osteoarthritis Outcome Score (KOOS) Pain Score — 2.92; 2.86; 3.03; 2.67 units on a scale — p=<0.05

Primary: Change in Moderate-to-vigorous Intensity Physical Activity — 0.7; 2.6; 2.7; 1.6 min/day of MVPA

Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared