Azithromycin to doxycycline switching in children with Mycoplasma pneumoniae pneumonia resistance gene positivity
Testing for resistance genes may guide antibiotic choices
This retrospective cohort study of 150 children with Mycoplasma pneumoniae pneumonia evaluated resistance gene expression and antibiotic man…
New evidence suggests that checking for resistance genes in children with pneumonia could help doctors decide when to switch antibiotics.
Prophylactic azithromycin during labor increases S. aureus resistance in mothers and infants
Azithromycin in Labor Raises Short-Term Resistance Risk
This RCT sub-study of 911 women and 915 infants found that prophylactic oral azithromycin during labor increased azithromycin resistance in …
This could change how we balance infection protection and antibiotic safety in childbirth.
Macrolide-resistant Mycoplasma pneumoniae prevalence at 94% in pediatric CAP cohort
Resistant pneumonia keeps kids sicker for days
This retrospective cohort of 71 pediatric patients in China found a 94.4% prevalence of macrolide-resistant M. pneumoniae. MRMP infections w…
In one Chinese hospital, 94% of child pneumonia cases resisted common antibiotics, leading to longer fevers and hospital stays.
ALIS plus macrolide regimen improves culture conversion in noncavitary MAC lung disease
An Inhaled Antibiotic Shifts the Odds in a Stealthy Lung Infection
In a 99-patient RCT of adults with noncavitary MAC lung disease, adding 6 months of amikacin liposome inhalation suspension (ALIS) to a macr…
Adding a nebulized antibiotic to standard pills helped more newly diagnosed MAC lung patients clear the bug sooner, with no new safety surpr…
Doxycycline-Quinolone Sequential Therapy Shows Lower Failure, Recurrence vs Azithromycin for MG
A New Strategy Cures a Stubborn STD Faster and Prevents Its Return
A retrospective cohort study of 1,192 NAAT-confirmed MG patients at a Chinese tertiary hospital found doxycycline-quinolone sequential thera…
Doctors now have clearer evidence for a better treatment plan to defeat a common, often-missed sexually transmitted infection.
Retrospective study links IVIG plus azithromycin to higher response rate in pediatric Mycoplasma pneumoniae pneumonia
When a Child's Pneumonia Won't Clear, This Add-On May Help
A single-center retrospective cohort of 140 children with Mycoplasma pneumoniae pneumonia found that adding intravenous immunoglobulin (IVIG…
Adding donor antibodies to standard antibiotics helped 97% of children with stubborn pneumonia recover, compared to 84% on antibiotics alone…
Intrapartum azithromycin reduces maternal infection risk regardless of time to delivery
Study finds timing of antibiotic in labor may not affect maternal infection prevention
A secondary analysis of an RCT in 29,236 pregnant patients found intrapartum azithromycin reduced maternal infection risk (RR 0.71) regardle…
Giving azithromycin during labor cuts maternal infection risk by 29% regardless of timing, but offers no protection for newborns.