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Home › Medications › cocaine

cocaine

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of cocaine

11 trials tracked of cocaine: 1 in phase 3 or 4 and 1 with published results. The most-cited published study has 32 citations.

11Trials tracked
1Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 1 Phase 2 2 Phase 1 8
  1. Phase 4 Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery Completed · 32 cited
  2. Phase 2 Intranasal Cocaine and Temperature Regulation During Exercise Completed
  3. Phase 2 Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse Completed
  4. Phase 1 Phendimetrazine and Cocaine Completed
  5. Phase 1 n-Acetylcysteine and Cocaine Completed
  6. Phase 1 Impact of Sustained Release d-Amphetamine on Choice Between Cocaine and a Non-Drug Reinforcer Completed
Show 5 more trials
  1. Phase 1 Cocaine and Zolmitriptan Completed
  2. Phase 1 Impact of a Non-Drug Choice on Cocaine Reinforcement Completed
  3. Phase 1 Reinforcing Effects of Cocaine During Phendimetrazine Maintenance Completed
  4. Phase 1 Neurobehavioral Mechanisms of Cocaine Choice Completed
  5. Phase 1 Suvorexant and Cocaine Completed

Showing the 11 most-cited and recently-updated of 11 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Self-medication of ADHD symptoms with psychoactive substances is predominantly inferred from association or motive reports
Psychiatry Guideline
Self-medication of ADHD symptoms with psychoactive substances is predominantly inferred from association or motive reports Mapping the Link Between ADHD and Substance Use Behaviors
This scoping review of 109 sources maps the literature regarding the self-medication of ADHD symptoms with stimulants, cannabis, nicotine, a…
New research maps how adults with ADHD may use substances like nicotine and cannabis to manage symptoms, though evidence remains mostly obse…
Frontiers Sep 30, 2026
Stimulant use is associated with increased social needs and severity in patients with opioid use disorder
Anesthesiology & Pain Medicine RCT
Stimulant use is associated with increased social needs and severity in patients with opioid use disorder Stimulant use linked to harder road for opioid treatment
This cross-sectional study examined the relationship between stimulant use and clinical outcomes in patients with opioid use disorder and co…
Patients using cocaine or methamphetamine face more severe symptoms and fewer treatment resources for opioid use and mental health issues.
Sep 6, 2026
Cocaine use is associated with higher mortality and surgical rates in ischemic colitis cases
Gastroenterology Meta-analysis
Cocaine use is associated with higher mortality and surgical rates in ischemic colitis cases Cocaine Use Linked to Severe Gastrointestinal Complications and Mortality
This narrative review examines gastrointestinal complications in patients with cocaine use. The review finds that cocaine-associated ischemi…
Cocaine use is linked to severe gastrointestinal issues, including higher mortality rates in cases of ischemic colitis compared to non-cocai…
Frontiers Sep 6, 2026
Maternal cocaine exposure is associated with neonatal deaths but lacks established lethal concentration thresholds
Pediatrics Meta-analysis
Maternal cocaine exposure is associated with neonatal deaths but lacks established lethal concentration thresholds Maternal Cocaine Exposure Linked to Infant Death Risk
This systematic review examines the toxicological patterns of neonatal deaths following maternal cocaine exposure. The review identifies sig…
New research highlights the link between maternal cocaine use and infant deaths, while noting the difficulty in finding a specific lethal do…
Frontiers Aug 27, 2026