PRISMA Scoping Review Examines Food-Drug Interactions in Cardiovascular and Diabetic Medications
Meals May Not Matter for Most New Heart and Diabetes Pills
This PRISMA scoping review synthesized data from 36 publications regarding food-drug interactions in cardiovascular and diabetic medications…
Most new heart and diabetes pills work the same whether you take them with food or on an empty stomach, but a few still need timing.
Genetic polymorphisms influence pharmacokinetics and bleeding risk for DOACs in meta-analysis
Your DNA May Explain Why Blood Thinners Work Differently for You
A meta-analysis of 39 studies involving 13,300 patients found that genetic polymorphisms (e.g., CES1, ABCB1) are associated with pharmacokin…
Tiny DNA differences may explain why the same blood thinner protects one person but causes bleeding in another.
Meta-analysis of DOACs versus conventional anticoagulation in Kawasaki disease with giant coronary artery aneurysms
Simpler Blood Thinners May Protect Kids' Damaged Heart Arteries
This systematic review and meta-analysis evaluated 594 children younger than 19 years with Kawasaki disease-associated giant coronary artery…
Children with the most serious heart complication of Kawasaki disease may soon swap daily shots for a once-a-day pill, with no drop in safet…
Factor XIa inhibitors show higher stroke risk but lower bleeding risk versus DOACs in atrial fibrillation
New blood thinners cut bleeding risk but triple stroke risk in heart rhythm patients
A meta-analysis of 3 RCTs in 16,845 patients with atrial fibrillation found Factor XIa inhibitors were associated with a 3.32 times higher r…
New blood thinners for atrial fibrillation cut bleeding risk by 59% but triple the risk of stroke, raising concerns they may be too gentle t…