Routine lab indicators help differentiate typical from incomplete Kawasaki disease and predict coronary lesions
Lab indicators may help identify Kawasaki disease risks
This retrospective study of 131 children with Kawasaki disease found that total protein was the only independent factor differentiating typi…
Routine blood markers could help doctors better identify Kawasaki disease types and predict potential heart complications in children.
Machine-learning model predicts coronary artery lesions in Kawasaki disease
Kids with rare heart condition may get faster help
This retrospective cohort study from a Chinese hospital developed a CatBoost machine-learning model to predict coronary artery lesions in Ka…
This tool could help doctors spot which kids face the highest risk of heart damage from Kawasaki disease — before it happens.
Prednisolone plus standard treatment did not significantly reduce coronary-artery lesions in newly diagnosed Kawasaki disease patients
Adding prednisolone to standard care did not prevent heart damage in Kawasaki disease patients
This multicenter, open-label, randomized, controlled trial evaluated 3208 participants with newly diagnosed Kawasaki disease in China.
Adding prednisolone to standard care did not prevent heart damage in Kawasaki disease patients, as lesion rates remained nearly the same.
Infliximab in IVIG-resistant Kawasaki disease with cholestatic hepatitis: case report
Can a new drug stop heart damage in Kawasaki disease when standard treatments fail?
A case report describes a 2-year-old Han Chinese male with IVIG-resistant Kawasaki disease and cholestatic hepatitis treated with infliximab…
In a two-year-old boy with Kawasaki disease, the drug infliximab quickly stopped his fever and liver trouble, yet his heart artery damage ke…
Meta-analysis of DOACs versus conventional anticoagulation in Kawasaki disease with giant coronary artery aneurysms
Simpler Blood Thinners May Protect Kids' Damaged Heart Arteries
This systematic review and meta-analysis evaluated 594 children younger than 19 years with Kawasaki disease-associated giant coronary artery…
Children with the most serious heart complication of Kawasaki disease may soon swap daily shots for a once-a-day pill, with no drop in safet…
Questions about Kawasaki disease
What lab factor helps predict coronary lesions in children with Kawasaki disease?
Routine lab indicators like C-reactive protein and erythrocyte sedimentation rate help predict coronary artery lesions in children with Kawasaki disease.
Full answer →Does adding prednisolone help reduce coronary artery lesions in newly diagnosed patients?
No, adding prednisolone to standard treatment did not significantly reduce coronary artery lesions at 1 month in newly diagnosed Kawasaki disease patients, according to a large randomized trial.
Full answer →Can a machine-learning model predict if a child will have coronary artery lesions?
Yes, machine-learning models can predict coronary artery lesions in children with Kawasaki disease, with some achieving high accuracy (AUC up to 0.95).
Full answer →