Systematic review of Dendrobium phenanthrene bioactivity across multiple disease models
Scientists found many plant chemicals that fight cancer and help diabetes in lab tests
This systematic review evaluates the bioactivity of 158 phenanthrene metabolites isolated from 53 Dendrobium taxa. The authors note that 64 …
A review of plant chemicals from Dendrobium plants shows strong activity against cancer and diabetes in lab studies. Most results come from …
Genetic polymorphisms influence pharmacokinetics and bleeding risk for DOACs in meta-analysis
Your DNA May Explain Why Blood Thinners Work Differently for You
A meta-analysis of 39 studies involving 13,300 patients found that genetic polymorphisms (e.g., CES1, ABCB1) are associated with pharmacokin…
Tiny DNA differences may explain why the same blood thinner protects one person but causes bleeding in another.
Meta-analysis finds increased bleeding with antithrombotic therapy during breast biopsy, but clinically relevant events are rare
Continuing blood thinners during breast biopsy increases minor bleeding but rarely serious problems
A systematic review and meta-analysis of 8 studies including 11,524 patients undergoing image-guided breast biopsy found that continuing ant…
Continuing blood thinners during a breast biopsy slightly increases minor bleeding but rarely causes serious problems like heart attacks or …
Research across Embolism and Thrombosis
Related studies from across the Embolism and Thrombosis family.
Endovascular therapy reduces post-thrombotic syndrome severity by 2.0 points compared to standard care
Endovascular Therapy Improves Quality of Life for Post-Thrombotic Syndrome
This randomized controlled trial of 225 patients with moderate or severe post-thrombotic syndrome and iliac-vein obstruction found that endo…
A new trial shows that endovascular therapy can reduce the severity of post-thrombotic syndrome and improve daily quality of life.
Systematic review and meta-analysis of machine learning models for deep vein thrombosis prediction in hospitalized adults
Machine learning models predict blood clots in hospitalized adults with high accuracy
This systematic review and meta-analysis synthesized evidence on machine learning-based prediction models for deep vein thrombosis in hospit…
A new analysis of 17 studies shows machine learning models can predict deep vein thrombosis in hospitalized patients with an accuracy score …
Meta-analysis finds modest PTS reduction with compression stockings after DVT
Long-term stockings lower risk of post-thrombotic syndrome in deep vein thrombosis patients
This meta-analysis of 1,775 patients with deep vein thrombosis evaluated long-term graduated compression stockings. It found a modest reduct…
A large review found long-term compression stockings modestly reduce the risk of post-thrombotic syndrome in people with deep vein thrombosi…
Meta-analysis finds education lowers DVT risk after orthopedic surgery
Teaching patients about DVT cuts risk after orthopedic surgery
This meta-analysis of six studies in orthopedic surgery patients found that education-based interventions were associated with a significant…
A review of studies finds that educating patients about deep vein thrombosis after orthopedic surgery can significantly lower their risk of …
External validation of three DVT prediction models in 1,270 acute stroke patients
Three DVT prediction models showed varying accuracy in a single-center stroke study
This single-center spatial validation cohort study assessed three deep vein thrombosis (DVT) prediction models in 1,270 patients with acute …
The Lu Qiufang model outperformed others with 82.1% accuracy in predicting deep vein thrombosis among 1,270 acute stroke patients at a Shenz…
Asthma associated with increased odds of venous thromboembolism, pulmonary embolism, and deep vein thrombosis in observational studies
Asthma Linked to Higher Risk of Blood Clots in Observational Data
This meta-analysis of observational studies involving patients with asthma found a statistically significant association between asthma and …
People with asthma face a 1.61 times higher risk of blood clots, with the danger of pulmonary embolism rising 2.41 times and deep vein throm…
Regional anesthesia with propofol sedation versus general anesthesia in unilateral total knee arthroplasty patients
Numb Legs, Faster Walks: New Knee Surgery Data
This retrospective cohort study evaluated 250 patients undergoing unilateral total knee arthroplasty to compare regional anesthesia with mon…
New knee surgery data shows regional anesthesia leads to faster walking and fewer readmissions without increasing dangerous blood clot risk.
FDA Approves Xarelto (rivaroxaban) for multiple indications including stroke prevention in nonvalvular atrial fibrillation and treatment of VTE
FDA approves a new blood thinner called Xarelto for several heart and clot conditions
The FDA approved rivaroxaban (Xarelto), a factor Xa inhibitor, for multiple indications including reducing stroke risk in nonvalvular atrial…
FDA approves new blood thinner Xarelto to prevent dangerous clots in heart conditions, deep vein issues, and after major surgeries.