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Home › Medications › furosemide

furosemide

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of furosemide

27 trials tracked of furosemide: 8 in phase 3 or 4 and 5 with published results. The most-cited published study has 180 citations.

27Trials tracked
8Phase 3 & 4
0Recruiting
5With published results
Phase distribution
Phase 4 4 Phase 3 4 Phase 2 6 Phase 1 7 Other / NA 6
  1. Phase 3 TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure Completed · 180 cited
  2. Phase 4 Nephropathy In Type 2 Diabetes and Cardio-renal Events Completed · 129 cited
  3. Phase 4 Diuretics and Dopamine in Heart Failure With Preserved Ejection Fraction Completed · 44 cited
  4. Phase 3 Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure Completed · 18 cited
  5. Phase 3 Furosemide vs. Placebo for Severe Antepartum Hypertension Completed · 7 cited
  6. Phase 4 Early Diuresis Following Colorectal Surgery Completed
Show 21 more trials
  1. Phase 4 Aquaresis Utility for Hyponatremic Acute Heart Failure Study Completed
  2. Phase 3 Lasix for the Prevention of De Novo Postpartum Hypertension Completed
  3. Phase 2 A Study of Ultra High Dose Diuretics to Treat Heart Failure Completed
  4. Phase 2 Aerosol Inhalation Treatment for Dyspnea Completed
  5. Phase 2 An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic Completed
  6. Phase 2 Aerosol Inhalation Treatment for Dyspnea - Patients Completed
  7. Phase 2 Single Dose of Furosemide to Improve Respiratory Distress in Moderate to Severe Bronchiolitis Completed
  8. Phase 2 The Effects of Decreasing the Lasix Dose on the Cardiorenal System Completed
  9. Phase 1 A Study in Healthy Men to Test Whether Zongertinib Influences the Amount of 4 Other Medicines (Dabigatran, Rosuvastatin, Metformin, and Furosemide) in the Blood Completed
  10. Phase 1 This Study Tests the Effect of Certain Medicines on the Transport of Other Medicines in the Body of Healthy Men Completed
  11. Phase 1 Transporter Cocktail Mutual Interaction Completed
  12. Phase 1 DDI (Effect of Metformin and Furosemide on Rosuvastatin PK) Completed
  13. Phase 1 Subcutaneous Furosemide in Acute Decompensated Heart Failure Pilot Completed
  14. Phase 1 Voxelotor CYP and Transporter Cocktail Interaction Study Completed
  15. Phase 1 Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study) Completed
  16. N/A B-type Natriuretic Peptide as a Surrogate Marker Guiding Post-operative Fluid Off-loading Completed
  17. N/A Protocol to Assess the Severity of Acute Kidney Injury Completed
  18. N/A The Effect of Loop Diuretics on Severity and Outcome of Acute Kidney Injury Completed
  19. N/A Measurement of Kidney Blood Flow and Oxygen Levels by MRI Completed
  20. N/A Peritoneal Dialysis vs Furosemide for Acute Kidney Injury After Cardiopulmonary Bypass Completed
  21. N/A A Study to Compare How Different Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Handled by the Body of Healthy People and People With Liver Cirrhosis Completed

Showing the 27 most-cited and recently-updated of 27 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Meta-analysis links vincristine and other drugs to higher cisplatin hearing loss risk in pediatric cancer
ENT (Otolaryngology) Meta-analysis
Meta-analysis links vincristine and other drugs to higher cisplatin hearing loss risk in pediatric cancer Hidden Danger in Kids' Cancer Treatment Raises Hearing Loss Risk
This meta-analysis of observational studies synthesized evidence on concomitant medications and cisplatin-induced hearing loss in pediatric …
• Four common drugs nearly quadruple hearing damage during chemo • Helps oncologists protect children from silent treatment side effects • D…
Frontiers May 14, 2026
Systematic review and meta-analysis finds no mortality benefit for alternative loop diuretics in chronic heart failure
Cardiology Meta-analysis
Systematic review and meta-analysis finds no mortality benefit for alternative loop diuretics in chronic heart failure Alternative heart failure diuretics show no mortality benefit but higher risk
This meta-analysis of 23 RCTs with 4902 patients with chronic heart failure found that alternative loop diuretics did not reduce all-cause m…
A review of 23 trials found alternative diuretics did not lower death risk in heart failure patients, but some raised safety concerns.
May 12, 2026
Furosemide plus hypertonic saline linked to lower biomarker increases after saline load in ADHF
Cardiology RCT
Furosemide plus hypertonic saline linked to lower biomarker increases after saline load in ADHF Study in 200 heart failure patients compares two intravenous diuretic treatment approaches
A randomized controlled trial of 200 patients with acute decompensated HFrEF found intravenous furosemide plus small-volume hypertonic salin…
Adding salt water to heart failure diuretics reduced stress markers in patients, but the study did not show if patients felt better or left …
Apr 2, 2026