Stapokibart plus glucocorticoids achieves disease control in elderly bullous pemphigoid patients
Trial shows stapokibart helps elderly bullous pemphigoid patients
In a single-center, retrospective, uncontrolled case series of 15 elderly patients with moderate-to-severe bullous pemphigoid, all achieved …
A small study found that adding stapokibart to standard therapy helped elderly patients with severe bullous pemphigoid control their skin di…
De-implementation of low-value bronchiolitis practices showed sustained adherence two years post-trial in a cluster RCT follow-up.
Doctors Stick to Better Bronchiolitis Care—2 Years Later
This cluster randomised controlled trial (cRCT) follow-up study assessed the sustainability of de-implementing low-value bronchiolitis pract…
It’s 2 a.m. in a busy children’s hospital.
Protocol for natural experiment examining glucocorticoids versus no glucocorticoids on opioid use in hip and knee arthroplasty
New Plan to Cut Pain Meds After Joint Surgery
This is a protocol for a natural experiment study (target trial emulation) in adults undergoing primary elective total hip, unicompartmental…
A new study aims to see if stronger steroids can reduce pain medicine needs after joint replacement.
Expert review outlines diagnostic and therapeutic management strategies for eosinophilic granulomatosis with polyangiitis.
Rare Lung and Blood Disease Gets a Smarter Treatment Map
This expert review addresses the management of patients with eosinophilic granulomatosis with polyangiitis (EGPA), focusing on glucocorticoi…
A new expert roadmap shifts treatment for rare EGPA disease from steroids to targeted biologic drugs for patients with stubborn asthma and o…
Meta-analysis links long-term glucocorticoid use and SLE duration to high osteoporosis prevalence in patients.
Lupus Patients Face Hidden Bone Loss Risk
This systematic review and meta-analysis evaluated 59 studies involving patients with systemic lupus erythematosus (SLE) to assess bone heal…
Bone loss affects 1 in 6 lupus patients, a hidden risk often overlooked due to the disease and its treatments.
Interstitial lung disease reduces achievement of rheumatoid arthritis treatment goals over 24 months
Why Interstitial Lung Disease Blocks Rheumatoid Arthritis Goals
This retrospective cohort study examined 254 patients with newly diagnosed rheumatoid arthritis who underwent chest CT within one year of on…
Rheumatoid arthritis treatments often fail to reach pain-free goals when the disease also attacks the lungs, making standard care harder for…
Japanese AAV Cohort Shows MPA Has 67.6% Five-Year Survival; Glucocorticoid Reduction Not Linked to Better Outcomes
For Japanese patients with a rare autoimmune disease, survival remains challenging.
A retrospective cohort study of 460 treatment-naïve Japanese patients with AAV found microscopic polyangiitis (MPA) had the poorest prognosi…
Japanese patients with microscopic polyangiitis face a five-year survival rate of 67.6%, as older age and kidney issues raise death risk.
Phase 2 trial tests pre-hospital glucocorticoid pulse in STEMI patients undergoing primary PCI
Phase 2 trial tests steroid pulse for heart attack patients before hospital arrival
A phase 2 randomized controlled trial enrolled 530 STEMI patients treated with primary PCI to test single-dose glucocorticoid pulse therapy …
A new trial tested giving a single steroid dose in ambulances before heart attack patients reach the hospital to reduce permanent heart dama…