Anatomical and immunological factors drive pathogenesis in plasma cell mastitis cases
New insights into the causes and treatment of mastitis
This narrative review synthesizes the etiology, clinical manifestations, and treatment strategies for plasma cell mastitis. It highlights ho…
Doctors are identifying how structural issues and immune responses lead to chronic inflammation in breast tissue, helping clarify treatment …
Ianalumab plus eltrombopag extends time to treatment failure in primary ITP adults
Study tests ianalumab plus eltrombopag for adults with immune thrombocytopenia
This phase 3 randomized, double-blind trial in 152 adults with primary ITP and insufficient response to glucocorticoids found that ianalumab…
Adding ianalumab to standard therapy helped more adults with immune thrombocytopenia stay stable and avoid treatment failure compared to pla…
Drug-induced osteoporosis mechanisms and gut microbiota links remain largely unresolved for most medication classes
Many common medicines might change gut bacteria and affect bone strength in older adults
This narrative review examines the association between medications such as glucocorticoids and aromatase inhibitors and gut microbiota alter…
Some drugs like antidepressants and seizure medicines can alter gut bacteria. Scientists are still studying if these changes hurt bones or c…
ERAS protocols may reduce opioid use and shorten stays for patients undergoing orthognathic surgery
ERAS protocols show promise for orthognathic surgery recovery
This narrative review examines the application of Enhanced Recovery After Surgery (ERAS) protocols in orthognathic surgery. The authors synt…
Enhanced Recovery After Surgery protocols may reduce opioid use and shorten hospital stays for patients undergoing jaw surgery.
Brepocitinib 30 mg improved Total Improvement Score versus placebo in dermatomyositis patients over 52 weeks
New Pill Eases Stubborn Muscle and Skin Disease Symptoms
This Phase 3, double-blind, randomized, placebo-controlled trial enrolled 241 adults with dermatomyositis. The once-daily oral brepocitinib …
• Brepocitinib 30 mg significantly improves muscle strength and skin rashes • Helps adults with treatment-resistant dermatomyositis regain d…
Stapokibart plus glucocorticoids achieves disease control in elderly bullous pemphigoid patients
Trial shows stapokibart helps elderly bullous pemphigoid patients
In a single-center, retrospective, uncontrolled case series of 15 elderly patients with moderate-to-severe bullous pemphigoid, all achieved …
A small study found that adding stapokibart to standard therapy helped elderly patients with severe bullous pemphigoid control their skin di…
De-implementation of low-value bronchiolitis practices showed sustained adherence two years post-trial in a cluster RCT follow-up
Doctors Stick to Better Bronchiolitis Care—2 Years Later
This cluster randomised controlled trial (cRCT) follow-up study assessed the sustainability of de-implementing low-value bronchiolitis pract…
It’s 2 a.m. in a busy children’s hospital.
Baseline vitamin D deficiency occurred in 73.08% of TAO patients receiving IVGC therapy with calcium supplementation
Simple Blood Test Could Predict Thyroid Eye Treatment Success
This retrospective cohort study evaluated 52 thyroid-associated ophthalmopathy patients treated with intravenous glucocorticoids and standar…
Checking vitamin D levels could help doctors choose the best treatment for thyroid eye disease.
Protocol for natural experiment examining glucocorticoids versus no glucocorticoids on opioid use in hip and knee arthroplasty
New Plan to Cut Pain Meds After Joint Surgery
This is a protocol for a natural experiment study (target trial emulation) in adults undergoing primary elective total hip, unicompartmental…
A new study aims to see if stronger steroids can reduce pain medicine needs after joint replacement.
Expert review outlines diagnostic and therapeutic management strategies for eosinophilic granulomatosis with polyangiitis
Rare Lung and Blood Disease Gets a Smarter Treatment Map
This expert review addresses the management of patients with eosinophilic granulomatosis with polyangiitis (EGPA), focusing on glucocorticoi…
A new expert roadmap shifts treatment for rare EGPA disease from steroids to targeted biologic drugs for patients with stubborn asthma and o…
Meta-analysis links long-term glucocorticoid use and SLE duration to high osteoporosis prevalence in patients
Lupus Patients Face Hidden Bone Loss Risk
This systematic review and meta-analysis evaluated 59 studies involving patients with systemic lupus erythematosus (SLE) to assess bone heal…
Bone loss affects 1 in 6 lupus patients, a hidden risk often overlooked due to the disease and its treatments.
Interstitial lung disease reduces achievement of rheumatoid arthritis treatment goals over 24 months
Why Interstitial Lung Disease Blocks Rheumatoid Arthritis Goals
This retrospective cohort study examined 254 patients with newly diagnosed rheumatoid arthritis who underwent chest CT within one year of on…
Rheumatoid arthritis treatments often fail to reach pain-free goals when the disease also attacks the lungs, making standard care harder for…