Narrative review discusses colorectal cancer metastasis patterns with immune checkpoint inhibitors and targeted therapies
Liver metastasis linked to resistance in colorectal cancer treated with immune checkpoint inhibitors
This narrative review examines response patterns to immune checkpoint inhibitors, anti-angiogenic agents, and targeted therapies in colorect…
A review of colorectal cancer treatments suggests liver metastasis is linked to resistance against immune checkpoint inhibitors, while lung …
Meta-analysis links emotional distress to worse outcomes in advanced lung cancer
Emotional distress linked to worse lung cancer survival
This systematic review and meta-analysis of 911 patients with advanced NSCLC found emotional distress was significantly associated with redu…
For people with advanced lung cancer, feeling emotionally distressed is tied to lower survival and worse treatment response, a new analysis …
Network meta-analysis compares therapies for liver metastatic uveal melanoma
Liver-directed therapy combined with ICIs leads for metastatic uveal melanoma survival
This systematic review and network meta-analysis synthesized evidence on therapeutic modalities for patients with liver metastatic uveal mel…
A network meta-analysis of 2,585 patients found liver-directed therapy combined with immune checkpoint inhibitors offered the best survival …
Systematic review of immune checkpoint inhibitors in cancer efficacy and safety
Immune Checkpoint Inhibitors Show Promise For Cancer Patients With High Tumor Burden
This systematic review synthesizes evidence from 15 randomized trials and cohort studies on immune checkpoint inhibitors in cancer. It finds…
A review of trials suggests immune checkpoint inhibitors work well for some cancer patients but carry risks like skin rashes and organ infla…
Review of antiviral and immunotherapeutic strategies for chronic hepatitis B
New antiviral strategies show promise for chronic hepatitis B infection
This narrative review synthesizes evidence on antiviral and immunotherapeutic strategies for chronic hepatitis B. The authors highlight func…
A review of new treatments suggests combination therapies may offer future value for managing chronic hepatitis B, cirrhosis, and liver canc…
Morning immune checkpoint inhibitor infusions associated with improved survival in metastatic non-small-cell lung cancer
Giving cancer immunotherapy in the morning may help patients live longer
This emulated pragmatic randomized controlled trial in Veterans Health Administration patients with stage IV non-small-cell lung cancer foun…
Giving immunotherapy in the morning instead of the afternoon appears to help advanced lung cancer patients live longer, a large study found.
Meta-analysis reveals CMR and biomarkers key in ICI myocarditis
Heart MRI and Blood Tests Help Detect Immunotherapy Heart Inflammation
In a meta-analysis of 3568 patients, abnormal CMR and elevated cardiac biomarkers were strongly associated with immune checkpoint inhibitor-…
A large review found that heart MRI and blood tests can help diagnose heart inflammation from immunotherapy, but no single test is enough on…
Review outlines immunotherapy roadmap for gastric cancer patients with noted limitations
New Immunotherapy Strategies May Help More Gastric Cancer Patients
This review examines immunotherapy options for patients with gastric cancer. The authors discuss various modalities including immune-checkpo…
New immunotherapy strategies could help more gastric cancer patients by turning cold tumors hot and personalizing treatment.
Meta-analysis finds Type 2 diabetes linked to poorer survival in solid tumor patients on immune checkpoint inhibitors
Patients with diabetes may face worse survival outcomes when treated with certain cancer drugs compared to those without diabetes
This meta-analysis of 1,225 participants with solid tumors treated with immune checkpoint inhibitors found that Type 2 diabetes was associat…
A large review found that people with type 2 diabetes had lower survival rates when using specific cancer medicines. This link was strong in…
Narrative review on immune microenvironment evolution in serrated neoplasia and colorectal cancer
New immune signals found in early colon growths before cancer starts
This narrative review synthesizes evidence on immune microenvironment evolution in serrated neoplasia pathway-associated tumors and colorect…
Scientists found immune system changes in early colon growths that could help predict which patients might benefit from new immune therapies
Narrative Review Explores Immune Checkpoint Inhibition in Pediatric Medulloblastoma
New immune targets offer hope for children with recurrent brain tumors
This narrative review discusses the potential of immune checkpoint inhibition via direct antibody targeting in pediatric medulloblastoma. Th…
A new generation of immune drugs is being tested to help children whose brain tumors have returned after standard treatment
Review of immune checkpoint inhibitor-associated diabetes mellitus in two patients
Diabetes Danger Lingers Months After Cancer Treatment Ends
This narrative review and case report describes two patients with immune checkpoint inhibitor-associated diabetes mellitus. The authors synt…
• Some patients develop dangerous diabetes long after stopping immunotherapy • Helps cancer survivors using newer immune-boosting drugs • St…