Review of antiviral and immunotherapeutic strategies for chronic hepatitis B
New antiviral strategies show promise for chronic hepatitis B infection
This narrative review synthesizes evidence on antiviral and immunotherapeutic strategies for chronic hepatitis B. The authors highlight func…
A review of new treatments suggests combination therapies may offer future value for managing chronic hepatitis B, cirrhosis, and liver canc…
Morning immune checkpoint inhibitor infusions associated with improved survival in metastatic non-small-cell lung cancer
Giving cancer immunotherapy in the morning may help patients live longer
This emulated pragmatic randomized controlled trial in Veterans Health Administration patients with stage IV non-small-cell lung cancer foun…
Giving immunotherapy in the morning instead of the afternoon appears to help advanced lung cancer patients live longer, a large study found.
Meta-analysis reveals CMR and biomarkers key in ICI myocarditis
Heart MRI and Blood Tests Help Detect Immunotherapy Heart Inflammation
In a meta-analysis of 3568 patients, abnormal CMR and elevated cardiac biomarkers were strongly associated with immune checkpoint inhibitor-…
A large review found that heart MRI and blood tests can help diagnose heart inflammation from immunotherapy, but no single test is enough on…
Review outlines immunotherapy roadmap for gastric cancer patients with noted limitations
New Immunotherapy Strategies May Help More Gastric Cancer Patients
This review examines immunotherapy options for patients with gastric cancer. The authors discuss various modalities including immune-checkpo…
New immunotherapy strategies could help more gastric cancer patients by turning cold tumors hot and personalizing treatment.
Meta-analysis finds Type 2 diabetes linked to poorer survival in solid tumor patients on immune checkpoint inhibitors
Patients with diabetes may face worse survival outcomes when treated with certain cancer drugs compared to those without diabetes
This meta-analysis of 1,225 participants with solid tumors treated with immune checkpoint inhibitors found that Type 2 diabetes was associat…
A large review found that people with type 2 diabetes had lower survival rates when using specific cancer medicines. This link was strong in…
Narrative review on immune microenvironment evolution in serrated neoplasia and colorectal cancer
New immune signals found in early colon growths before cancer starts
This narrative review synthesizes evidence on immune microenvironment evolution in serrated neoplasia pathway-associated tumors and colorect…
Scientists found immune system changes in early colon growths that could help predict which patients might benefit from new immune therapies
Narrative Review Explores Immune Checkpoint Inhibition in Pediatric Medulloblastoma
New immune targets offer hope for children with recurrent brain tumors
This narrative review discusses the potential of immune checkpoint inhibition via direct antibody targeting in pediatric medulloblastoma. Th…
A new generation of immune drugs is being tested to help children whose brain tumors have returned after standard treatment
Review of immune checkpoint inhibitor-associated diabetes mellitus in two patients
Diabetes Danger Lingers Months After Cancer Treatment Ends
This narrative review and case report describes two patients with immune checkpoint inhibitor-associated diabetes mellitus. The authors synt…
• Some patients develop dangerous diabetes long after stopping immunotherapy • Helps cancer survivors using newer immune-boosting drugs • St…
Early time-of-day immune checkpoint inhibitor administration improves overall survival in advanced solid tumors
Cancer Patients Live Longer When Immunotherapy Starts Early in Day
This systematic review and meta-analysis evaluated 6129 patients with advanced solid tumors receiving immune checkpoint inhibitors. Earlier …
• Morning immunotherapy shots link to longer survival for advanced cancers • Helps patients fighting lung stomach kidney and other tough can…
Neoadjuvant ICI plus chemotherapy improves event-free survival in early-stage TNBC
Adding immune drugs to chemo helps early stage triple negative breast cancer patients stay disease free longer
A meta-analysis found neoadjuvant immune checkpoint inhibitors with chemotherapy significantly improved event-free survival but not overall …
A large review of trials found that adding immune checkpoint inhibitors to chemotherapy improves survival chances for early stage triple neg…
High tumour mutation burden improves overall survival in solid tumours treated with immune checkpoint inhibitors
High Mutation Counts May Predict Better Cancer Survival Outcomes
This systematic review and meta-analysis evaluated 5278 patients with solid tumours treated with immune checkpoint inhibitors or chemotherap…
High mutation counts in tumors may help predict who will survive longer when taking powerful immune-boosting cancer drugs
Systematic review and meta-analysis shows immune checkpoint inhibitors improve survival in first-line ES-SCLC but not as single agents in second-line
Immune drugs boost survival in small-cell lung cancer
This systematic review and meta-analysis evaluates immune checkpoint inhibitors combined with chemotherapy versus chemotherapy alone for ext…
Adding immune checkpoint inhibitors to chemotherapy helps patients with extensive-stage small-cell lung cancer live longer.