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Oncology
Review of PBMC processing conditions in head and neck squamous cell carcinoma treatment-naive patients
New blood test method avoids risky biopsies for cancer patients
This observational study review examines peripheral blood mononuclear cell (PBMC) processing conditions for treatment-naive patients with he…
A new blood processing method lets doctors track immune health without risky biopsies for head and neck cancer patients.
medRxiv
May 1, 2026
Oncology
Cohort
Radiotherapy de-escalation strategies show reduced toxicity but modest clinical benefits in head and neck cancer cohorts.
Smarter Radiation for Head and Neck Cancer May Spare Patients Misery
This narrative review examines radiotherapy de-escalation strategies for head and neck squamous cell carcinoma and HPV-related oropharyngeal…
Doctors are testing gentler radiation plans that protect quality of life for people with throat, mouth, and neck cancers facing harsh side e…
Frontiers
Apr 15, 2026
Oncology
Cohort
Local brain therapies associated with reduced mortality in HNSCC patients with brain metastasis
Local brain treatments linked to modest survival gains in rare head and neck cancer cases
This retrospective cohort analysis evaluated 201 patients with head and neck squamous cell carcinoma and brain metastasis from three tertiar…
Local brain treatments linked to lower death risk for rare head and neck cancer patients who develop brain metastases, though most still die…
Frontiers
Apr 14, 2026
Allergy & Immunology
Cohort
Breg-related gene signature predicts survival and immune landscape in head and neck squamous cell carcinoma.
Your Immune System Holds a Hidden Clue to Head and Neck Cancer Survival
This cohort study analyzed patients with head and neck squamous cell carcinoma (HNSCC) using bioinformatics data from TCGA and GEO databases…
A new eight-gene test predicts head and neck cancer survival better than standard measures, helping doctors identify which patients might be…
Frontiers
Apr 10, 2026
Genetics & Precision Medicine
Phase II
Regional motif diversity score in cfDNA predicts pembrolizumab response in head and neck cancer
Can a DNA pattern predict who will heal from head and neck cancer immunotherapy?
A phase II trial in 68 patients with locally advanced, resectable HNSCC found that a regional motif diversity score (rMDS) in cell-free DNA …
A new DNA pattern in blood can reliably predict which head and neck cancer patients will respond to immunotherapy and live longer without th…
medRxiv
Apr 6, 2026