N/A N=928 Little Cigar and Cigarillo Warnings for Youth
Little Cigars and Cigarillos (LCC) Use
Primary: Willingness to Use Little Cigars Cigarillos (LCCs) — 2.86; 3.08; 2.99 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=1,578 The Impact of Cigarillo Warnings on Purchasing
Cigar Smoking
Primary: Average Total Number of Cigarillos Purchased — 6.33; 6.28; 6.64; 4.98 cigarillos
N/A N=764 Cigarillo Warnings Image Sorting Study
Smoking, Cigar
Primary: Intention to Quit Smoking Cigarillos in the Next 30 Days at Weeks 2-4 — 2.47; 2.49; 2.34; 2.44 units on a scale
N/A N=65 Addictive Potential of LCCs in Dual Users
Tobacco Use Disorder · Dual Tobacco Use · Tobacco Dependence
Primary: Demand Elasticity — 0.027; 0.032 cigarettes/dollar
N/A N=1,029 Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs
Tobacco Use
Primary: LCC Quit Intentions — 2.9; 2.49; 2.54 score on a scale
Early Phase 1 N=95 The Effect of Sweet Flavoring on the Rewarding and Reinforcing Value of Cigarillo Use Among Young Adults
Tobacco Use · Cigar Smoking
Primary: Subjective Rewarding Value of Cigarillo Flavoring — 4.03; 3.63; 3.30 score on a scale
N/A N=139 Cigarette Smoking Among Young Adults
Cigarette Smoking · Smoking Behaviors
Primary: Puff Topography — 1108; 1045.2; 1084.6 mL
N/A N=31 Cigarette Smoking in Smokers With and Without Schizophrenia
Tobacco Dependence · Schizophrenia
Primary: End-of-session Carbon Monoxide — 62.7; 43.0 parts per million (ppm)
N/A N=40 Acute Effects of Cigarette Packaging and Charcoal Filtration on Perceptions, Use Behaviors, and Harm Exposure
Smoking Behaviors
Primary: Number of Puffs Taken (Video-scored Smoking Behavior Outcome 1) — 15.8; 16.7; 19.1; 19.6 puffs
Phase 2 N=35 Comparison Between Marijuana Smoked in Cigarette Paper Versus Cigar Paper
Marijuana Dependence
Primary: Plasma THC — 6; 53; 70; 7 ng/mL
N/A N=31 Impact of Exclusive Use of Low Nicotine Cigarettes on Compensatory Smoking
Smoking
Primary: Breath Sample (Expired Carbon Monoxide) — 18.77; 31.07; 25.38; 30.49 parts per million — p=0.92
N/A N=199 Perceptions of Cigarette Smoking in Young Adults
Smoking, Cigarette
Primary: Subjective Response to Smoking Cigarettes From the Cigarette Evaluation Scale — 4.68; 4.50 score on a scale — p=>.05
Phase 2 N=130 Health Effects of SLT, Cigarette Smoking, and New Tobacco Products
Nicotine Dependence
Primary: Toxicant Exposure by Products — 835.3; 782.1; 726.8; 0.157 ng/ml — p=0.002
N/A N=184 Brain Nicotine Receptor Density in Veteran Smokers
Positron Emission Tomography
Primary: PET Scan, Rating Scales — 7.1; 8.6; 7.9; 8.0 Vt/fp or mL/cm3
N/A N=60 Smoking Topography and Harm Exposure in Menthol Cigarettes
Cigarette Smoking Toxicity
Primary: Smoking Topography- Puff Volume — 518; 661; 650; 620 mL
N/A N=136 Reduced Nicotine Content Cigarettes and Tobacco Switching Behaviors
Tobacco Addiction · Dual Tobacco Use
Primary: Number of Days Using Alternative Products — 14; 26; 20 Number of days
N/A N=1,257 Effects of FDA Authorized Smokeless Tobacco Claims Among US Adults Who Smoke Cigarettes
Tobacco Product Beliefs and Use
Primary: General Relative Harm Perception — 3.04; 2.76; 2.84; 3.19 score on a scale
N/A N=187 Effects Among Smokers Who Use and Do Not Use E-Cigarettes
Toxicant Exposure
Primary: Toxicant Exposure — 40; 97 pg/ml
N/A N=36 Palatability of Experimental Cigarettes - Study 2
Smoking
Primary: Change in UrineTotal Nicotine Equivalent (TNE) Between Baseline and Week 1 — -16.2; -7.6; 1.3 nmols/ml
N/A N=10 IQOS (Non-Cigarette Tobacco Product) Pilot Study
Smoking · Tobacco Use
Primary: Number of Participants Who Prefer IQOS — 7 Participants
N/A N=5 Effects of Smoking State on Decision Making
Behavior
Primary: Effort Based Decision Making — 29.5; 18.3 high effort selections
N/A N=150 Methods Project 4: Clinical Trial
Smoker
Primary: Smoke-free Days — 14.5; 0; 0 days
N/A N=37 Cigarette Smoking Decision Study
Tobacco Smoking
Primary: Demand Intensity as Assessed by a Behavioral Economic Demand Curve — 4.709677419; 2.580645161 puff bouts
N/A N=50 Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes
Smoking Cessation · Harm Reduction · E-Cig Use
Primary: Effects of Devaluation on Switching From Cigarettes to the JUUL E-cigarette — 4; 4 Participants
N/A N=33 Impact of Switching to Non-Menthol Cigarettes Among Smokers
Tobacco Use
Primary: Total Number of Cigarettes Smoked — 2.2 cigarettes per day
N/A N=80 Low Nicotine Cigarettes Plus Electronic Cigarettes
Tobacco Dependence
Primary: Urinary NNAL (4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol) — 505.6; 459.1; 373.3; 180.5 pg/mg creatinine — p=0.017
Phase 4 N=179 Smoking Tobacco and Drinking Study
Smoking · Heavy Episodic Drinking
Primary: Number of Participants With Reported 7-day Point Prevalence Abstinence at 3 Months — 3; 4 Participants
Phase 4 N=134 Smoking Cessation in Hispanic Construction Workers
Smoking Cessation
Primary: Prolonged Abstinence Rates — 36.00; 30.43 Percentage of participants
N/A N=67 Clinical Trial Tobacco Marijuana
Cannabis Use Disorder · Tobacco Use Disorder
Primary: Tobacco Quit Attempts — 13; 17 Participants — p== 0.33
N/A N=34 Strengthening Instrumental Extinction to Prevent Smoking Relapse (VLNCCue)
Cigarette Smoking
Primary: Change in Fagerstrom Test of Nicotine Dependence Score — .67; 1.33 score on a scale — p=0.39