Phase 2 N=73 Cognitive Stimulation
Substance Use Disorders
Primary: Working Memory — 0.86; 0.04 digits recalled
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=75 Cognitive Behavior Therapy and Work Outcome
Schizophrenia
Primary: Work Quality — 3.01; 3.23; 3.33 scores on a scale
N/A N=22 Brain and Cognitive Changes After Reasoning Training in Individuals With Mild Cognitive Impairment
Mild Cognitive Impairment
Primary: Change From Baseline in California Verbal Learning Task Score — 3.04; 5.17; 4.22; 7.04 score on a scale
N/A N=49 Applying a Person-Centered Approach to Enhance Cognitive Training in Senior Living Community Residents With Mild Cognitive Impairment
Mild Cognitive Impairment
Primary: Mean Change in ADL Score From Baseline to Week 10 — 0.00; -0.29 score on a scale
N/A N=591 Using Counter Attitudinal Advocacy to Change Drinking Behavior
Alcohol Drinking · Alcohol Abuse
Primary: Drinks Per Week as Assessed by the Daily Drinking Questionnaire — 6.8; 6.0; 7.1 drinks per week — p=.646
N/A N=287 Examining the Effectiveness of Cognitive Training
Cognitive Change
Primary: Proportion of Correct Targets Identified Minus False Identifications in the n-Back Task — .80; .70; .68; .21 score on a scale
N/A N=108 Cognitive and Emotional Skills to Aid Smoking Prevention
Tobacco Smoking
Primary: Specific Aim 1: Percentage of Participants Who Attended 13 or More Interventions — 41.0; 50; 40.5 percentage of participants
N/A N=114 Improving Adherence to Cognitive Rehabilitation
Psychosis
Primary: Number of Sessions Attended — 7.70; 4.98 sessions — p=0.24
N/A N=46 Targeting Self-regulatory Deficits Through Cognitive Remediation Intervention
Drug Use Disorders
Primary: Change in Stop Signal Reaction Time — -8.62 ms — p=.003
N/A N=27 Reasoning Training in Individuals With Bipolar Disorder
Bipolar Disorder · Cognitive Ability, General
Primary: Change From Baseline: Test of Strategic Learning — 2.35; 3.04 score on a scale — p=0.040
N/A N=95 Cognitive Training for Diabetes Self-Management
Diabetes Mellitus, Type 2
Primary: Change in A1C at Week 22 — -1.5; 1.0 percentage of glycated hemoglobin
N/A N=40 Preventing Cognitive Decline
Cognitive Decline
Primary: Percentage of Trials Correct On Working Memory Test — 87.69; 91.57; 88.01; 91.68 percentage of correct trials — p=>0.05
N/A N=6 Cognitive Rehab for Parkinson's
Parkinson's Disease · Mild Cognitive Impairment
Primary: Change in NIH Sponsored Executive Abilities: Measures and Instruments for Neurobehavioral Evaluation and Research (NIH-EXAMINER) Executive Composite Score — 0.34; -.42…
N/A N=68 Augmenting Hospitalization for Serious Mental Illness: Cognitive Bias Modification
Depression · Bipolar Disorder · Anxiety Disorders
Primary: Clinical Global Improvement Scale (CGIS) — 14; 20 Participants
N/A N=95 Cognitive Dysfunction In Parkinson's
Parkinson's
Primary: Differences in Error Rates on the NBack Task Between Real and Sham Stimulation Trials — -0.79; -0.1 incorrect responses
N/A N=96 Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology
Anxiety Symptoms · Depressive Symptoms
Primary: Change in Children's Depression Inventory (CDI) From Baseline to 9-month Follow-up — 12.35; 11.76; 11.54; 11.66 scores on a scale
N/A N=162 Growth Mindset Psychoeducation for Modifiable Risk Factors for CMD
Depression, Anxiety
Primary: Patient Health Questionnaire (PHQ-9; Kroenke, Spitzer & Williams, 2001) — 5.50; 4.57; 6.70; 13.14 units on a scale
N/A N=45 CBT Enhanced With Social Cognitive Training
Depression
Primary: Faux Pas Recognition Test — 0.901; 0.854 score on a scale — p=< 0.05
N/A N=72 Cognitive Training Trial
Attention Deficit Hyperactivity Disorder
Primary: Total ADHD Symptom Score From Vanderbilt ADHD Parent Rating Scale — 27.00; 26.63 units on a scale — p=.36
N/A N=78 Neuromodulation Enhanced Cognitive Restructuring: A Proof of Concept Study
Anxiety · Depression · Personality Disorders
Primary: Time to Return to Heart Rate Baseline During the Regulation Period During Training — 1.591; 1.828; 1.505; 1.534475 log (seconds) — p=0.019
N/A N=21 Improving Memory Performance by Applying Cognitive Training
HIV
Primary: Change in Working Memory — 51.33; 43.15 mean T score on working memory tests — p=.013
Phase 4 N=61 Neurocognitive Benefits of a Weight Management Program
Overweight and Obesity
Primary: Blood Oxygen Level-dependent (BOLD) Response to High-calorie Foods Cues Minus Neutral Objects in Left Anterior Cingulate Cortex — -0.05; -0.16 percent BOLD signal change
N/A N=194 The Impact of Reactivation During Sleep on the Consolidation of Abstract Information in Humans
Memory Consolidation
Primary: Structure Knowledge for a New Modular Category in Stage 2 — 0.563; .5726; .6303; .6266 Proportion of correct responses
N/A N=13 EEG Changes With Guided Online Meditation
Meditation
Primary: Number of Participants With EEGs to Measure Changes in Wave Oscillations — 3; 4 Participants with Evaluable EEGs
N/A N=72 Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol
Anxiety Disorders · Depression · Posttraumatic Stress Disorder
Primary: Change in Cognitive Performance — 4.92; 8.18; .27 score on a scale
N/A N=213 Cognitive Training for Nicotine Dependence
Tobacco Use Disorder · Nicotine Addiction
Primary: Point-prevalence Abstinence at End of Treatment — 38; 43 Percentage of participants — p=0.14
N/A N=69 Cognitive Training for Patients With Schizophrenia
Schizophrenia · Schizoaffective Disorder · Other Primary Psychotic Disorders
Primary: UCSD Performance-based Skills Assessment Total Score (Measures Functional Capacity) — 82.7; 84.4 units on a scale
N/A N=167 Cognitive Training in Parkinson Study
Parkinson Disease · Impaired Cognition · Alteration in Cognition
Primary: Accuracy on the Tower of London Task — 81.2; 82.3; 88.1; 84.0 percentage of correct responses
N/A N=110 Cognitive Rehabilitation for PD
Parkinson's Disease
Primary: Wechsler Adult Intelligence Scale-IV (WAIS-IV) Matrix Reasoning Test Total Scaled Score — 0.22; 0.42 score on a scale — p=0.6662
N/A N=107 Cognitive Training and Neuroplasticity in Mild Cognitive Impairment
Mild Cognitive Impairment · Memory Disorders · Memory Impairment
Primary: Change in the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) — -0.89; 0.55 score