N/A N=3,256 Hand Hygiene and Hospital Acquired Infections
Complication of Surgical Procedure
Primary: Number of Participants With Postoperative Healthcare Acquired Infections — 108; 116 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=530 Clinical Characteristics and Microbiology of Healthcare Associated Pneumonia
Healthcare Associated Pneumonia
Primary: Pathogens of Healthcare Associated Pneumonia, Measured by the Number of Participants — 15; 51; 195; 269 Participants
N/A N=33 Enhanced, Personalized and Integrated Care for Infection Management at the Point-Of-Care
Antibiotic Resistant Infection · Infection
Primary: Percentage of Appropriate Antimicrobial Prescriptions Recommended — 90 percentage of prescriptions appropriate
Phase 4 N=110 S. Aureus Screening and Decolonization
Wound Infection Due to Staphylococcus Aureus · MRSA Infection of Postoperative Wound
Primary: Eradication of Staphylococcus Aureus (SA) Carriage at All 4 Body Sites Tested. — 13; 41 Participants
N/A N=25,732 Pulsed UV Xenon Disinfection to Prevent Resistant Healthcare Associated Infection
Healthcare Associated Infection · Clostridium Difficile Infection · Infection Due to Multidrug Resistant Bacteria
Primary: Number of Environmentally-implicated Healthcare-Associated Infections (eiHAIs) Associated With the Additional Use of a PX-UV Disinfection Compared to Standard Terminal…
N/A N=418 Targeted Infection Control in Long-term Care
Infection
Primary: Total Number of MDRO (Multidrug Resistant Organisms) Isolated — 1299; 1732 Total Number of MDRO isolates — p=<0.05
N/A N=339,902 Active Bathing to Eliminate Infection (ABATE Infection) Trial
Healthcare Associated Infections · Methicillin Resistant Staphylococcus Aureus · Multi Drug Resistant Organisms
Primary: MRSA and VRE Clinical Cultures — 0.87; 0.79 Hazard Ratio (Intervention vs Baseline) — p=0.17
N/A N=60 Safe Critical Care: Testing Improvement Strategies
Central Line-associated Bloodstream Infection (CLABSI) · Ventilator Associated Pneumonia
Primary: CLABSI and VAP Rates — 1.84; 2.42; 2.24; 2.47 events/1000 device days — p=<.05
Phase 3 N=2,518 Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit
Nosocomial Infections
Primary: Bacteremia — 3.52; 4.93 events per 1000 at-risk days
N/A N=350 Trial of 2% Chlorhexidine Bathing on Nosocomial Infections in the Surgical Intensive Care Unit
Cross Infection · Pneumonia, Ventilator-associated · Catheter-related Infections
Primary: Incidence of Nosocomial Infection — 15; 30 participants — p=0.049
Phase 2 N=99 Reducing Urinary Tract Infection Rates Using a Controlled Aseptic Protocol for Catheter Insertion
Urinary Tract Infections · Catheter Infection · Catheter-Related Infections
Primary: Number of Participants With a Catheter Associated Urinary Tract Infection (CAUTI) — 7; 6 Participants
N/A N=16 Community Central Line Infection Prevention Trial
Infection
Primary: Total Number of Central Line Associated Blood Stream Infections (CLABSI) — 113; 84; 123; 109 infections
N/A N=109 Bacterial Contamination of Healthcare Worker Uniforms
Bacterial Contamination of Healthcare Worker Uniforms
Primary: Total Bacterial Contamination of Healthcare Worker Uniform With Antimicrobial Properties Compared to Standard Healthcare Worker Uniform After an 8-hour Workday. — 41…
N/A N=149 Hub Cleansing to Prevent Hub Infection
Bacteremia
Primary: Number of Central Venous Catheter Hubs With Internal Contamination — 42; 18; 39; 14 contaminated hubs
Phase 4 N=7 Human Microbiome and Healthcare Associated Infections - Nursing Home Dwelling Older Veterans
Human Microbiome
Primary: Change in the Abundance of Staphylococcus Aureus in the Nose After Decolonization — -4174 fg/uL
N/A N=93,476 INSPIRE Trial for Abdominal Infections
Abdominal (ABD) Infection
Primary: Extended-Spectrum Days of Antibacterial Therapy (ES-DOT) Per Empiric Day — 68616; 68679; 76605; 50001 Extended-Spectrum Days-of-Therapy
N/A N=1,687 Hospital Design and Risk of Nosocomial Infections: A Prospective Controlled Trial
Vancomycin Resistant Enterococci Infection · Clostridium Difficile Infection · Nosocomial Infection
Primary: Incidence Density of Hospital-acquired Infection With Clostridium Difficile (CDI), and Hospital-acquired Infection or Colonization With Vancomycin-resistant Enterococcus…
N/A N=83 Improving Oral Care to Reduce Hospital-Acquired Pneumonia (HAP) in the Acute Neurologically Impaired Adult
Pneumonia
Primary: Hospital Acquired Pneumonia Occurrences — 2; 13 participants
N/A N=1,518 Cost-Effectiveness Study Comparing Chlorhexidine Bathing With Active Surveillance Cultures to Prevent Methicillin-resistant Staphylococcus Aureus & Other Hospital Infections
Staphylococcal Infections
Primary: Acquisition of Methicillin-resistant Staph Aureus (MRSA) Colonization or Infection — 9; 10 participants — p=>0.05
N/A N=2,905,455 CLUSTER Trial for Outbreak Detection and Response
Cluster Detection
Primary: Cluster Size — 1.81; 1.41 outbreak cases after first signal
N/A N=200 Gown and Glove Use to Prevent the Spread of Infection in VA Community Living Centers
Methicillin-Resistant Staphylococcus Aureus
Primary: MRSA Transmission — 0.20; 0.02; 0.11; 0.01 Proportion of swabs positive for MRSA
N/A N=58 Building an Optimal Hand Hygiene Bundle
Hand Hygiene · Health Care Associated Infection · Compliance
Primary: Hand Hygiene Compliance — -0.4; 1.8; -1.3; -3.7 percentage of change in HH compliance
N/A N=1,209 Reduction of Catheter-associated Urinary Tract Infection With a Daily Nursing Review of the Indication
Urinary Tract Infections · Urinary Tract; Accessory
Primary: Rate of Catheter-associated Urinary Tract Infection — 10; 12 infections per 1000 days
N/A N=325 Preventing the Spread of Infection in Nursing Homes
Staphylococcus Aureus
Primary: Rates of Staphylococcus Aureus Acquisition: Percentage of Short Stay Participants Who Acquired MRSA or MSSA (or Both) During the Study Period — 17; 8 Participants
Phase 4 N=1,088 Reducing Catheter-Related Bloodstream Infections in the ICU With a Chlorhexidine-Impregnated Sponge (BIOPATCH)
Catheter-related Bloodstream Infection
Primary: The Number of Catheter Related Bloodstream Infections (BSI) /1000 Catheter Days in Both Arms — 4.74; 4.72 BSIs /1000 catheter days — p=0.05
N/A N=203 Impact Of Bacterial Resistance On Healthcare Costs For Hospitalized Patients With Complicated Intra-Abdominal Infections
Complicated Intra-Abdominal Infection
Primary: Duration of Hospitalization — 14.1 Days
N/A N=57,837 INSPIRE Trial for Skin and Soft Tissue Infections
Skin and Soft Tissue (SST) Infection
Primary: Extended-Spectrum Days of Antibacterial Therapy (ES-DOT) Per Empiric Day — 43305; 40156; 43927; 30287 Extended-Spectrum Days-of-Therapy
N/A N=190 Enhanced Room Cleaning in Intensive Care Units to Reduce Gown and Glove Contamination With Multi-drug-resistant Bacteria
Infection Control
Primary: Contamination of Disposable Isolation Gown and Gloves With Methicillin-resistant Staphylococcus Aureus or Multi-drug-resistant Acinetobacter Baumannii — 20.5; 17.2…
N/A N=55,412 The INSPIRE-ASP UTI Trial
Urinary Tract Infection (UTI)
Primary: Extended-Spectrum Days Of Antibacterial Therapy (ES-DOT) Per Empiric Day — 35023; 25987 Extended-Spectrum Days-of-Therapy
Phase 4 N=112 Evaluation of Two Hand Hygiene Products in ICUs
Hand Hygiene Effectiveness
Primary: Bacterial Colony Forming Units Present on Hand Prints After Time Spent in Common Areas — 2.17; 1.81 log(10) transformed CFU