N/A N=4,231 Circulation Improving Resuscitation Care (CIRC)
Cardiac Arrest · Cardiopulmonary Resuscitation
Primary: Hospital Discharge — 196; 233 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=15 ECPR for Refractory Out-Of-Hospital Cardiac Arrest
Cardiac Arrest · Heart Arrest · Sudden Cardiac Arrest
Primary: Emergency Department Arrivals Under 30 Minutes — 5 Participants
Phase 2 N=48 Ubiquinol as a Metabolic Resuscitator in Post-Cardiac Arrest
Cardiac Arrest
Primary: Coenzyme Q10 Plasma Levels — 185; 207; 113; 441 ng/mL
N/A N=28 Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest
Cardiopulmonary Arrest · Pediatric ALL · Resuscitation
Primary: Median Alveolar Ventilation — 276; 370 ml
N/A N=30 Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot
Cardiac Arrest
Primary: Attrition — 0; 0 Participants
N/A N=168 Predicting Mortality in Patients With Return of Spontaneous Circulation After Cardiac Arrest
Post-Resuscitation Syndrome · Critical Illness · Cardiac Arrest
Primary: 30-Day Mortality — 112 participants
N/A N=5 Biological Response of Trauma Patients to Standard Trauma Resuscitation Therapy
Hemorrhagic Shock
Primary: Biological Response as Characterized by Selected Cytokines, Specifically Tumor Necrosis Factor Alpha (TNFα), Interleukin One (IL-1β), and Interleukin Six (IL-6).
N/A N=5 Pre-hospital ECMO in Advanced Resuscitation in Patients With Refractory Cardiac Arrest. ( SUB30 )
Death, Sudden, Cardiac · Out-Of-Hospital Cardiac Arrest · Ventricular Fibrillation
Primary: Proportion of Patients Successfully Established With Pre-hospital ECPR — 0 Participants
Phase 1 N=16 Reoxygenation After Cardiac Arrest II (REOX II Study)
Cardiac Arrest
Primary: Plasma Isofurans (pg/mL)/Isoprostanes (pg/mL) Ratio
Phase 2 N=14 Amantadine to Speed Awakening After Cardiac Arrest
Coma · Heart Arrest · Anoxia
Primary: Rate of Awakening (Number of Patients Who Are Able to Follow Commands) — 2; 2 Participants
N/A N=9 Chest Compression and Sustained Inflation
Newborn Infants Having Asystole or Bradycardia at Birth
Primary: Time Needed to Achieve Return of Spontaneous Circulation — 31; 138 seconds — p=0.05
Phase 2 N=1,586 Automated Real-time Feedback on CPR Study
Heart Arrest
Primary: Rate of ROSC During the Prehospital Resuscitation — 361; 345 Participants — p=0.96
N/A N=48 Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest
Cardiac Arrest · Sudden Cardiac Death
Primary: Mean Systolic and Diastolic Blood Pressures — 80.38; 121.21; 61.37; 15.52 mmHg
N/A N=142 Preemptive Resuscitation for Eradication of Septic Shock
Sepsis · Severe Sepsis
Primary: Number of Participants With Worsening Organ System Dysfunction Defined by SOFA Score Increase ≥ 1 — 34; 20 Participants — p=0.064
Phase 2 N=2 Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest
Cardiac Arrest
Primary: Intervention Compliance — 1 participants
N/A N=14 Open Pilot Trial of a Mind-body Program for Cardiac Arrest Survivors and Their Caregivers
Emotional Distress · Cardiac Arrest
Primary: Recruitment Feasibility Assessed by the Number of Eligible Dyads Enrolled — 7 dyads
N/A N=27 SI + CC Versus 3:1 C:V Ratio During Neonatal CPR
Heart Arrest · Birth Asphyxia · Bradycardia
Primary: Return of Spontaneous Circulation — 90; 615 seconds
Phase 4 N=337 Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation
Acute Respiratory Failure · Intubation Complication
Primary: Number of Participants With Cardiovascular Collapse — 33; 31 Participants
Phase 2 N=10 Coenzyme Q10 in Post-Cardiac Arrest Cerebral Resuscitation
Cardiac Arrest · Sudden Cardiac Arrest
Primary: Prevalence of Low Serum CoQ10 Levels in Cardiac Arrest Patients — 0.706; 0.66 ug/mL
N/A N=63 Neonatal Resuscitation - Sustained Inflations
Premature Birth
Primary: Expiratory Tidal Volume — 153; 194 ml/kg/min
Phase 2 N=50 Bicarbonate in Patients With Out-of-hospital Cardiac Arrest
Cardiac Arrest · Metabolic Acidosis
Primary: Return of Spontaneous Circulation (ROSC) — 4; 16 ROSC percents of each group
Phase 2 N=397 Calcium for Out-of-Hospital Cardiac Arrest
Heart Arrest, Out-Of-Hospital
Primary: Number of Participants With Sustained Return of Spontaneous Circulation — 37; 53 Participants
Phase 3 N=501 Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest
Heart Arrest
Primary: Number of Participants With Return of Spontaneous Circulation — 100; 86 participants
N/A N=42 Time to Accurate Heart Rate on Neonatal Outcomes
Premature Infant · Extremely Low Birth Weight · Extreme Prematurity
Primary: Time to Heart Rate Display in iRes Warmer With Resusview — 16; 50 seconds from time of birth
N/A N=200 Pre-ROSC Intra-Nasal Cooling Effectiveness
Cardiac Arrest
Primary: Achieve Return of Spontaneous Circulation (ROSC) — 33; 43 participants
N/A N=3,004 Pragmatic Airway Resuscitation Trial
Cardiac Arrest
Primary: Number of Patients Alive at 72 Hours After Episode. — 230; 275 Participants
N/A N=542 A Pilot Study of Intra-arrest Therapeutic Hypothermia in Patients Suffering Non-Traumatic Out of Hospital Cardiac Arrest
Out-of-Hospital Cardiac Arrest
Primary: Number of Participants Who Survived Up To Hospital Discharge — 24; 40 Participants
N/A N=336 Ultra-Brief Versus Brief Hands Only CPR Video Training With and Without Psychomotor Skill Practice
Cardiac Arrest
Primary: Median Compression Depth (mm) — 30; 41; 42; 48 millimeters — p=.05
Phase 3 N=1,497 Clinical Trial of Sodium Nitrite for Out of Hospital Cardiac Arrest
Out-Of-Hospital Cardiac Arrest
Primary: Number of Participants Who Survived to Hospital Admission — 218; 205; 212 Participants — p=0.82
N/A N=298 Three Different Cardiopulmonary Resuscitation (CPR) Training Methods
Cardiopulmonary Resuscitation
Primary: CPR Depth — 43.7; 42.2; 35.3 millimeters