N/A N=51 Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs
Hypotension · Anesthesia
Primary: Number of Participants Who Had Hypotensive Events — 8; 21 Participants — p=0.01
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=60 Propofol EC50 for Inducing Loss of Consciousness in General Combined Epidural Anesthesia
Gastric Cancer
Primary: Propofol EC50 for Inducing Loss of Conciousness — 2.97; 3.36 ug/ml
N/A N=30 Assessment of Cognitive Function After Surgery in Two Types of Anesthesia in Patients Operated for Breast Cancer
Patients With Breast Cancer and Breast Surgery Requiring
Primary: Presence of Cognitive Impairment — 29.5; 29 score on a scale
N/A N=54 Ketamine Infusion and Hypoventilation
Hypoventilation
Primary: Intraoperative Hypoventilation — 1.2; 65 % time
N/A N=31 Characterizing the Electroencephalogram Signature of Fentanyl During Induction of General Anesthesia
Anesthesia
Primary: Slope of EEG Theta Band Power Over Fentanyl Effect Site Concentration (dB/ng/mL) — 0.55 dB / nano gram / mL
Phase 4 N=50 Alternative Sedation During Bronchoscopy
Sedation
Primary: Decreased Minute Ventilation — 0.736; 0.764 percentage of baseline — p=<0.0001
N/A N=40 Desflurane Versus Propofol in the Sitting Position
Cerebral Ischemia
Primary: Regional Cerebral Oxygen Satuation (rSO2) — 77.4; 72.5; 76; 70 percentage of rSO2 (%)
Phase 4 N=192 Impact of Propofol Reduction in Anesthesia Induction
Propofol Adverse Reaction · Anesthesia
Primary: Systolic Blood Pressure Variation — 26; 23; 18; 22 percentage of variation
Phase 4 N=75 Comparison of Etomidate Plus Propofol, Etomidate Alone on Induction of Anesthesia
Surgery
Primary: Blood Pressure — 105; 122; 117.88 mmHg
N/A N=68 Optimal Sevoflurane Concentration for Intubation in Combination of Clincal Remifentanil Doses
Postoperative Pain
Primary: EC50 for Successful Intubation in Each Groups — 3.00; 2.00; 1.29 vol%
Phase 4 N=50 Dexmedetomidine vs Propofol TIVA (Total Intravenous Anesthesia) and Interscalene Block
Shoulder Pain
Primary: Number of Participants That Need an Airway Intervention. — 0; 5 participants
Phase 4 N=32 Angiotensin II in General Anesthesia
Hypertension
Primary: Median Dose Required to Increase the Systolic Blood Pressure (SBP) — 35; 43; 45 ng/kg/min
Phase 4 N=41 Cognitive Functions After TIVA With Dexmedetomidine
Postoperative Confusion
Primary: Mini Mental State Examination (MMSE) Score at the Second Hour After Surgery — 27.40; 26.45 scores on a scale
Phase 4 N=135 Propofol vs. Midazolam-based Balanced Propofol for Nonanesthesiologist Moderate Sedation in Colonoscopy
Procedural Sedation
Primary: Level of Sedation Throughout the Entire Procedure — 22; 9; 10; 1 participants
N/A N=81 Optimal Dose of Combination of Rocuronium and Cisatracurium
Chronic Otitis Media · Anesthesia
Primary: Onset of Neuromuscular Blocking Agents(NMBAs) — 212.8; 230.1; 399.3 Second
Phase 4 N=56 Ketamine and Propofol for Upper Endoscopy
Anesthesia
Primary: Dose of Propofol Required to Prevent Movement (Response) to Insertion of Endoscope Into the Patient's Esophagus — 6.1; 4.5; 4.7; 1.1 mg/kg
N/A N=199 Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly
Lumbar Spondylosis · Cervical Spondylosis · Hip Osteoarthritis
Primary: Change in Neurocognitive Performance (Z-score) — .09; -.20; -.42; .01 z score
Phase 2 N=20 Optimization of Desflurane in Elderly Patients
Postoperative Cognitive Dysfunction
Primary: The Time From the End of Anesthesia to Extubation — 329.0; 636.0 second
Phase 4 N=798 Ancillary Effects of Dexmedetomidine Sedation After Cardiac Surgery
Heart Disease
Primary: Number of Patients With Atrial Arrhythmia — 121; 134 Participants — p=0.34
N/A N=32 Addition of Nitrous Oxide and Its Effects on Depth of Anesthesia
Deep Sedation · Anesthesia, General
Primary: The Effect of Nitrous Oxide on Bispectral Index (BIS) and State Entropy Index (SE) — 36; 40; 32; 39 units on a scale
N/A N=100 the Impact of Noise on Requirements of Anesthetics During General Anesthesia
Anesthesia
Primary: Requirements of the Inhalational Anesthetic Desflurane, Measured in Expiratory Volume Percentage, to Maintain a BIS-Index Triggered Depth of Anesthesia — 3.6; 3.7…
N/A N=4,000 Estimate the Behavior of Chinese Anesthesiologists Practicing General Anesthesia With Sevoflurane
Anesthesia, General
Primary: Anesthesiologist Satisfaction With the Anesthesia Recorded at the End of the Operation Using a Numeric Analog Scale (NAS) — 8.85 units on a scale
Phase 3 N=80 Propofol in Obese Children
Pharmacodynamics · Obesity
Primary: Dose of Propofol That Caused Loss of Consciousness in 95% (ED95) of Obese and Non-obese Children — 2; 2.125 mg/kg
Phase 4 N=2,367 Randomized Trial of Sedative Choice for Intubation
Acute Respiratory Failure
Primary: All-cause, 28-day, In-hospital Mortality — 330; 345 Participants
Phase 4 N=102 Propofol for Pediatric Tracheal Intubation With Deep Anesthesia During Sevoflurane Induction
Anesthesia Intubation Complication
Primary: Estimated Propofol Doses Producing 50% Excellent Intubation Conditions — 1.48; 0.00; 0.07; 2.35 mg/kg
Phase 4 N=80 Effects of Epidural Local Anesthetics on Propofol Induction
General Anesthesia · Propofol Target-controlled Infusion · Thoracic Epidural Anesthesia
Primary: Propofol Effect-site Concentration — 1.76; 1.14; 1.09; 1.04 ug/ml
Phase 4 N=173 Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy
Hypoxemia
Primary: Effect Site Concentration When Conscious Level Reaches OAAS-3 — 2.3; 2.2; 2.5; 2.2 ug/ml
N/A N=60 Conscious Sedation for Epilepsy Surgery
Epilepsy
Primary: Patients Satisfaction — 6.33; 6.45 score on a scale
N/A N=121 Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia
Emergence Delirium
Primary: Emergence Agitation — 3.9; 2.5 Score on a scale — p=0.001
N/A N=85 A Comparison of Desflurane vs. Sevoflurane and the Time to Awakening and the Incidence and Severity of Cough
Surgery · Anesthesia
Primary: Time to Awakening — 6.8; 11.8 Elapsed time in minutes