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Anterior uveitis

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Anterior uveitis

10 trials tracked for Anterior uveitis: 3 in phase 3 or 4 and 2 with published results. The most-cited published study has 18 citations.

10Trials tracked
3Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 4 1 Phase 3 2 Phase 2 3 Other / NA 4
  1. Phase 3 Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis Completed · 18 cited
  2. Phase 3 Suprachoroidal Injection of CLS-TA in Patients With Non-infectious Uveitis Completed · 9 cited
  3. Phase 4 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients Completed
  4. Phase 2 Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis Completed
  5. Phase 2 Human Anti-Tac (Daclizumab) to Treat Juvenile Idiopathic Arthritis (JIA)-Associated Uveitis Completed
  6. Phase 2 Topical Interferon Gamma for Macular Edema Secondary to Uveitis Completed
Show 4 more trials
  1. N/A Retinal OCT and (mfERG) Related to Age, Sex, and the Use of Anti-inflammatory Medications Completed
  2. N/A MAGNOLIA: Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301 Completed
  3. N/A Ocular Sarcoidosis Open Label Trial of ACTHAR Gel Completed
  4. N/A PEMF: an Adjunct Therapy for Anterior Uveitis Completed

Showing the 10 most-cited and recently-updated of 10 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found For clinicians

Anterior uveitis: what the trials found

Suprachoriodal administration of 4mg CLS-TA has demonstrated significant clinical improvements in patients with anterior uveitis. Specifically, it resulted in a statistically significant number of subjects achieving at least a 15-letter improvement from baseline in best corrected visual acuity at 24 weeks (p<0.001) 2.

Clinical markers of inflammation and haze associated with CLS-TA suprachoriodal injection show high rates of resolution. Patients treated with 4mg CLS-TA demonstrated a Grade of 0 in anterior chamber flare (34/38), anterior chamber cells (31/38), and vitreous haze (34/38) 3. Additionally, H.P. ACTHAR subcutaneous gel injection was associated with the reduction of photographic haze to Grade 0 or down by two steps 1.

The use of 4mg CLS-TA suprachoriodal injection did not show a statistically significant difference in the time to additional therapy for uveitis compared to the control group (p=0.562) 8.

Recent results — preliminary, needs further review

  • Reduction in central subfield thickness was observed following 4mg CLS-TA treatment in subjects with macular edema following uveitis (-164.44 vs -78.20; p=0.0017) 4.
  • Repository Corticotropin Injection showed a 3% improvement in visual acuity and a 2% resolution of intraocular inflammation 7.
  • Diclofenac was evaluated for its impact on macular thickness in uncomplicated anterior uveitis (p=0.018) 10.

For the clinician treating this condition

  • Suprachoriodal 4mg CLS-TA is associated with significant improvements in visual acuity and high rates of resolution for anterior chamber cells, flare, and vitreous haze.
  • H.P. ACTHAR subcutaneous gel injection may be utilized to reduce photographic haze in patients with uveitis.
  • Suprachoriodal 4mg CLS-TA did not significantly alter the time until additional therapy was required for uveitis.

AI synthesis of 7 cited trials, updated Jul 8, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.