Lung Diseases, Obstructive

All Lung Diseases, Obstructive Articles

• Yoga and Baduanjin improve lung function while Tai Chi improves quality of life in COPD
• Resveratrol improves pulmonary function and reduces inflammation in animal models of chronic obstructive pulmonary disease
• Stathmin implicated in cancer and non-neoplastic diseases, potential biomarker and therapeutic target
• Inhaled treprostinil is the only approved therapy with randomized evidence for pulmonary hypertension associated with interstitial lung disease
• High intensity exercise training improves dyspnoea management across multiple chronic respiratory and neuromuscular conditions
• COPD and OSA overlap syndrome is associated with greater disease burden than either condition alone
• Host-targeting antivirals offer a potential transformative treatment strategy for rhinovirus infection
• Extreme diurnal temperature range increases risk of asthma related visits in children and adolescents
• SHVASAN model aims to improve rural screening and diagnosis of asthma and COPD
• Intravenous magnesium sulfate serves as secondary adjunctive therapy for severe refractory acute asthma exacerbations
• Ultrasound Assessment of Diaphragm Function for Predicting Weaning Success in AECOPD Patients
• Low-dose thrombolysis reduces bleeding risk compared to full-dose therapy in intermediate-risk pulmonary embolism
• Cognitive frailty prevalence reaches 32% among older adults with heart failure
• Pulmonary TB History Linked to Higher COPD Odds
• Liquid biopsy-derived multimodal models outperform CT-based evaluation for pulmonary nodule diagnosis
• COPD patients have higher odds of diabetes mellitus with an adjusted OR of 1.39
• Multimodal gene prioritization improves predictive performance of polygenic transcriptome risk scores for asthma
• Fermented dairy consumption and reduced risk of asthma or wheeze in children
• HFNC shows significantly lower adverse event rates than CPAP in children with bronchiolitis
• SPECT V/Q-based diagnostic strategy shows comparable 3-month VTE risk to CTPA and planar V/Q
• CDQ yields highest sensitivity and AUC for identifying patients with chronic obstructive pulmonary disease
• C-reactive protein testing impacts antibiotic prescribing rates in acute COPD exacerbations
• Cloud-based intelligent management system improves medication adherence 89.2% vs 58.0% in pediatric asthma
• Depemokimab maintains trough concentrations 90% above EC level with predicted half-life of 47 days
• Asthma and COPD are associated with significantly increased risk of pertussis infection
• High-dose omega-3 PUFA and EPA significantly reduce risk of asthma and wheezing in children
• Chlorinated pool air exposure is linked to mucosal irritation and asthma-like symptoms in swimmers
• Maternal hypertensive disorders of pregnancy are associated with increased offspring asthma risk
• Treatable traits protocol aims to reduce exacerbations in AECOPD patients
• CXCL16/CXCR6 axis exerts bidirectional regulatory influence on neoplasms and inflammatory disorders like asthma
• Type 2 monoclonal antibodies reduce annual moderate-to-severe exacerbations in patients with eosinophilic COPD
• Low-dose N-acetylcysteine reduces acute exacerbation risk in patients with chronic obstructive pulmonary disease
• Health literacy-sensitive self-management programs improve exercise capacity and symptom burden in patients with COPD
• Biologic therapies targeting T2 inflammatory pathways reduce exacerbation rates in COPD patients
• Predictors of Polysomnography Progression in Children with Mild Sleep-Disordered Breathing
• Upstream alarmins IL-33 and TSLP emerge as key targets in T2 asthma pathogenesis
• Readmission rates for COPD patients increase from 15.2% at 1 month to 42.10% at 1 year
• Age, male sex, low BMI, and comorbidities like diabetes are significant risk factors for sepsis incidence
• Genetic variants in OSTN and common haplotypes are associated with increased residual pulmonary vascular obstruction
• Genetic Architecture of Pulmonary Artery Diameter and Shared Systemic Vascular Biology
• Corticosteroids, IVIG, antibiotics, and mechanical ventilation are associated with higher odds of invasive pulmonary aspergillosis
• Health literacy is moderately associated with improved self-care behaviors in patients with multiple chronic diseases
• Type-2 targeted biologics reduce moderate-to-severe exacerbations in patients with eosinophilic or type 2 COPD
• Energy therapies improve exercise capacity and quality of life in patients with chronic obstructive pulmonary disease
• Genetic variant identification improves polygenic risk prediction for patients with asthma
• Three-variable stratification tool identifies risk of invasive pulmonary aspergillosis in SFTS patients
• HFNC reduces treatment failure and PICU stay in pediatric bronchiolitis compared to LFNC
• PEFR-guided therapy shows no difference in symptom control compared to symptom-guided therapy in acute asthma
• BiPAP improves oxygenation over HFNC in pediatric asthma exacerbation, but evidence is limited
• Over one-third of workers with occupational asthma experience adverse occupational outcomes
• Inspiratory muscle training improves inspiratory muscle strength and exercise tolerance in stable COPD patients
• Purified phytochemicals and multicomponent botanical formulas may modulate the pulmonary fibrosis immune microenvironment in IPF
• Bidirectional associations exist between obstructive lung diseases and inflammatory bowel disease across 30 observational studies
• Routine serum lipid profiles may serve as markers for systemic metabolism in allergic diseases
• Vitamin D supplementation alleviates symptoms of allergic rhinitis, atopic dermatitis, and urticaria
• Elevated SII is significantly associated with increased COPD risk, all-cause mortality, and respiratory failure
• TCM decoctions combined with conventional treatment improve FEV1 and PEF in pediatric asthma
• Extreme temperature exposure may worsen COPD outcomes in Chinese populations, protocol outlines
• Respiratory biofeedback and neurofeedback offer potential frameworks for managing multi-component dyspnea in COPD patients
• Interval likelihood ratios improved correct management decision rates by 11.2 to 18.3 percentage points
• Metabolic abnormalities are significantly associated with pulmonary infections and asthma exacerbations in children
• Necroptosis emerges as pathogenic hub in asthma, linking type 2 inflammation and steroid resistance
• COPD caregiver health literacy is low, assessment tools lacking, scoping review finds
• Robotic-assisted CT-guided transthoracic needle biopsy reduces radiation exposure and complication rates for pulmonary nodules
• Coexisting COPD and Atrial Fibrillation are associated with increased risk of mortality and bidirectional disease association
• Omalizumab may improve asthma and food allergy in a pediatric liver transplant recipient
• Oral bacterial lysates reduce wheezing frequency and infection rates in children with asthma
• Evaluating the Impact of Digital Health Interventions on Chronic Disease Self-Care Outcomes
• Polygenic risk scores validate IL-1 signaling role in childhood asthma, supporting IL1R1 antagonist repurposing
• Pharmacist-led telepharmacy may improve medication adherence and reduce blood pressure in patients with NCDs
• Structured physical activity improves FEV1% predicted by 5.79 and PAQLQ scores in patients with asthma
• Structured exercise improves 6-minute walk distance by 38.62 m in idiopathic pulmonary fibrosis
• Ultra-processed food consumption is associated with metabolic syndrome, cardiovascular risk, and allergic diseases in children
• System-level strategies and task-shifted care improve equity in global allergic disease management
• IoT-assisted pulmonary rehabilitation protocol for moderate-to-severe stable COPD patients in single institution
• Casirivimab plus imdevimab reduced risk of hospitalization or death in patients with and without asthma
• Maternal free vitamin D linked to offspring asthma risk
• Higher preoperative NLR and SII show increased risk for postoperative pneumonia and pulmonary complications in lung and esophageal surgery
• COPD patients show heightened sympathetic nerve activity compared to healthy adults
• 1 in 7 COPD patients decline or discontinue long-term PAP therapy, meta-analysis finds
• HLA-DPA1 and HLA-DPB1 expression is downregulated in pediatric asthma with high diagnostic value
• Diabetes mellitus linked to higher SSI risk after hernia repair, other factors not significant
• FAM13A variants influence tissue destruction in COPD and fibrotic remodeling in pulmonary fibrosis
• Anti-inflammatory reliever therapy outperforms SABA-only in asthma management
• Combination voriconazole and micafungin improved a boy with CGD and invasive Aspergillus lentulus infection
• Prenatal beta-2-adrenergic agonist exposure linked to increased ASD risk with aOR 1.34 preconception
• Pirfenidone reduces lung cancer incidence by 73% in IPF patients with a pooled risk ratio of 0.39
• Telemedicine strategies improve asthma control and quality of life in adults
• Tubeless thoracic surgery may reduce pain and hospital stay in pulmonary nodule resection, though long-term safety remains unconfirmed
• Ultrasound-facilitated catheter-directed alteplase reduces early recurrence in intermediate-risk pulmonary embolism
• Respiratory microbiome composition in children offers new ideas for precision treatment of respiratory diseases and asthma
• Genetic variants and environmental factors like PM2.5 exposure may increase asthma risk in susceptible individuals
• Network meta-analysis of exercise interventions for COPD rehabilitation
• Review of animal models for allergic fungal airway disease and asthma
• Case report details multimodal treatment for aggressive thyroid carcinoma
• Systematic review finds vitamin D supplementation offers no lung function benefit for children with asthma
• Meta-analysis identifies rare gene-trait associations across 1.2 million individuals in global biobanks
• Meta-analysis finds ADHD linked to asthma but no causal effect in children
• Speleotherapy improves asthma control and breathing patterns in patients with respiratory conditions
• Systematic review links specific TCM constitutions to worse COPD outcomes in 2,168 patients
• Subcutaneous astegolimab reduced COPD exacerbations in phase 2b and 3 trials versus placebo
• Telenursing review shows reduced COPD and asthma exacerbations and hospitalizations
• Systematic review maps 50 most-cited articles on pediatric respiratory infections
• COPD guideline proposes cellular phenotype classification for targeted therapy
• Narrative review on vitamin D and VDR in gastrointestinal and pulmonary diseases
• Review of 16 cases shows 25% mortality for pulmonary mucormycosis in DKA patients treated with amphotericin B
• Systematic review and meta-analysis links D-dimer and ultrasound findings to recurrent venous thromboembolism risk
• Immediate smoking cessation support increases 12-month quit rates in adults with chronic airway diseases
• Narrative review of Europe-licensed anti-asthmatic biologics for severe pediatric asthma notes limited pediatric evidence
• Systematic review and meta-analysis on cold air bronchial challenge test for asthma diagnosis
• Review reframes COPD therapy toward integrated death program modulation by inflammatory endotype
• Meta-analysis shows exercise training improves depressive and anxiety symptoms in 1208 COPD patients
• Systematic review on nocebo effect induction in chronic conditions and clinical communication
• Review of metabolism-driven acylation modifications in COPD pulmonary cells
• Narrative review discusses EV-associated non-coding RNAs in paediatric asthma
• Switching Biologics in Severe Asthma Patients Shows Improved Clinical Outcomes and Reduced Exacerbations Across Multiple Therapies
• Systematic review and meta-analysis on face-directed fan therapy for dyspnea in advanced disease
• Expert consensus guidelines for N-acetylcysteine use in various respiratory conditions
• Meta-analysis finds balance training improves balance in COPD patients receiving pulmonary rehabilitation
• Meta-analysis shows biologic therapies reduce annual exacerbations in COPD patients with high eosinophils while maintaining safety profiles
• FDA Approves Breztri Aerosphere (budesonide/glycopyrrolate/formoterol) for COPD Maintenance
• Resistance Training with Photobiomodulation Improves Muscle Strength in Difficult-to-Control Asthma
• Systematic review and meta-analysis of Yupingfeng Powder for bronchial asthma in adults
• Review of animal models shows unclear causal links between microbial dysbiosis and pulmonary fibrosis
• Higher dietary inflammation linked to increased COPD risk in UK Biobank cohort
• Evidence-based review of transducer selection for lung ultrasound in dogs and cats with pulmonary pathology
• Nurse and social worker telecare team intervention improved quality of life in high-risk patients with COPD, heart failure, or interstitial lung disease
• Higher Intraoperative Mechanical Power Linked to Impaired Oxygenation and Pulmonary Complications After Orthopedic Surgery
• Dry NaCl Inhalation Fails to Improve Mucociliary Clearance in COPD
• Emergency-use spacers improve salbutamol delivery in asthmatics compared to pMDI alone
• Repeated counseling with pMDI devices reduced inhalation errors in adult asthma patients compared to pMDI alone
• Montelukast vs Tiotropium Added to ICS in Children With Asthma
• Nurse-led rehabilitation consultation improves asthma control in primary care
• New propellant HFA-152a in BDP/FF/G pMDI shows similar efficacy to HFA-134a in asthma
• Systematic review and meta-analysis links swimming pool attendance to increased asthma risk in children
• Meta-analysis finds childhood asthma linked to higher risk of obstructive sleep apnea
• SABR shows worse survival in ultracentral pulmonary oligometastases compared to nonultracentral tumors
• Meta-analysis shows benzodiazepine receptor PAMs improve sleep but increase long-term COPD risks in patients with insomnia
• Pulmonary barotrauma incidence and risk factors in non-HIV PCP patients
• Case report and literature review on pulmonary thromboembolism after vertebroplasty
• Chinese herbal medicine adjunct therapy reduced recovery time and MDR bacterial counts in older adults with pulmonary infection
• Narrative review examines multimorbidity impact on sepsis morbidity and mortality outcomes
• Meta-analysis shows pharmaceutical care improves asthma and COPD management outcomes in 4173 patients
• Umbrella review associates processed meat consumption with higher risks of cancer and chronic disease outcomes
• mMRC dyspnea scale correlates with risk stratification and 1-year outcomes in acute pulmonary embolism patients
• Smartphone app-based music PR program improves walking distance in COPD patients
• Software validation report shows single biomarkers often outperform panels for breast cancer diagnosis
• Retrospective analysis shows machine learning improves CT-based airway and emphysema mapping
• Review of genetic risk variants in idiopathic pulmonary fibrosis among non-European individuals shows limited transferability
• Systematic Bioinformatics Review Maps Asthma Molecular Architecture Across Thirty-One Cell Types
• Early-Life Exposures Linked to Childhood Asthma in Canadian Cohort
• Narrative review proposes framework for TWAS signature-matching in drug prioritization
• EMS Bundle for Pediatric Life-Threatening Asthma Evaluated in PECARN Pilot
• Narrative review discusses tezepelumab for severe asthma in type 2-low patients on GINA Step 4–5 therapy
• Serum specific IgE testing reveals dust mite sensitization in 37.0% of patients with allergic diseases in Ningbo, China
• Systematic review links hypertension, diabetes, and pulmonary inflammation; SGLT2 inhibitors show potential
• Systematic review and meta-analysis of pharmacist-led care in COPD
• Meta-analysis of 15 observational studies links e-cigarette use to higher COPD odds
• Systematic review links gut-lung axis in COPD and inflammatory bowel disease
• AI-Based Adjudication of MACE Events Shows High Agreement with Human CEC in MI Trial
• Clinical-immuno-inflammatory signature for Aspergillus–Mucorales co-infection in ICU patients
• FeNO measurement shows limited diagnostic performance for asthma in school-age children
• mNGS on BALF samples shows higher pathogen detection in pulmonary infections vs. conventional testing
• Network meta-analysis of acupuncture interventions for acute exacerbation of chronic obstructive pulmonary disease
• De-implementation of low-value bronchiolitis practices showed sustained adherence two years post-trial in a cluster RCT follow-up
• Single-center retrospective study associates ferritin and eosinophil levels with acute asthma exacerbation in children
• Benralizumab reduces asthma exacerbations in severe eosinophilic asthma patients over 24 weeks
• Review of UK Biobank data identifies plasma protein mediators in cardiometabolic disease progression
• Meta-analysis identifies DNA methylation markers linked to asthma exacerbations in diverse pediatric populations
• Observational biobank study compares phenomic and social determinants for disease risk prediction
• Polygenic risk scores improve identification of rare variant carriers in idiopathic pulmonary fibrosis patients
• Combined digital and paper audit feedback did not improve asthma prescribing versus digital-only in primary care
• Adjuvanted RSV vaccine shows efficacy against RSV disease in older adults with comorbidities
• Feasibility study abstract evaluates home spirometry and FeNO for asthma diagnosis in adults
• Narrative review examines lung microbiome and mucosal IgA in chronic inflammatory lung diseases
• Multicomponent breathing and exercise program improves breathlessness mastery in moderate to severe COPD
• Systematic review and meta-analysis of pulmonary telerehabilitation versus center-based care in COPD
• Systematic review finds high relapse rates in pulmonary sarcoidosis across diverse study designs
• Relaxation training and early benzodiazepines linked to respiratory recovery in adults with COPD, pneumonia, asthma, bronchiectasis, or interstitial lung disease
• Acupuncture with lung-large intestine theory improves asthma exacerbation outcomes versus conventional therapy
• Systematic review evaluates anti-IL-5 and anti-IL-5Rα biologics for eosinophilic respiratory and systemic diseases
• RT-RN HFNC weaning pathway linked to shorter PICU stay in critical bronchiolitis
• Concurrent training improves exercise capacity and quality of life in older COPD patients
• Case report describes multidrug-resistant Candida tropicalis IPFD misdiagnosed as malignancy before caspofungin response
• Narrative review links rare earth element exposure to respiratory symptoms and lung disease in industrial settings
• Subcarinal angle and biomarkers associated with mortality in ICU COPD patients
• Strategies to screen and reduce adverse events in patients with asthma using systemic corticosteroids
• Systematic review examines miRNA-mediated neutrophil regulation for acute lung injury, asthma, fibrosis, and lung cancer
• AI nomogram predicts malignancy risk in surgically resected pulmonary nodules ≤3 cm
• Occupational toxic particle exposure linked to increased pulmonary sarcoidosis risk in meta-analysis
• Systematic review examines IL-5-targeted and multi-target therapies for eosinophil-associated diseases including asthma and COPD
• In hospitalized children with human rhinovirus infection, lower airway obstruction and specific comorbidities associate with progression to bronchitis or pneumonia
• Peri- and postmenopausal hormonal changes may exacerbate asthma, rhinitis, cough, allergies, hypersensitivity, anaphylaxis, and angioedema
• Budesonide-glycopyrronium-formoterol fumarate dihydrate improved lung function and reduced severe exacerbations versus budesonide-formoterol in inadequately controlled asthma
• Virtual wards and hospital at home show no survival or readmission benefit for ECOPD patients compared to hospital admission
• 5-factor frailty index predicts postoperative pulmonary infection but not pneumothorax or effusion after lung resection
• Meta-analysis links asthma, passive smoking, and frequent snacks to recurrent respiratory infections in preschoolers
• EMG measurement is feasible in primary care for stable mild to moderate COPD patients
• Rapamycin therapy reduced infections and lymph node size in a female child with APDS1
• Mepolizumab plus FESS improved lung function and symptoms versus mepolizumab alone in severe CRSwNP