HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Drug Pipeline
Sys. Review
Literature review synthesizes Schisandra chinensis effects on gut microbiota and metabolic pathways across multiple conditions
This Ancient Berry May Quiet Inflammation From Your Gut to Your Brain
This literature review examines the potential of Schisandra chinensis regarding gut health and metabolic regulation.
An ancient berry used for centuries may rebalance gut bacteria to calm inflammation linked to digestive issues, liver disease, diabetes, and…
Frontiers
Apr 19, 2026
Drug Pipeline
RCT
AI endoscopic score shows better agreement with ulcerative colitis remission than Mayo score in RCT
AI endoscopic scoring shows better agreement with ulcerative colitis symptoms in trial
This phase 3 RCT in 387 subjects with ulcerative colitis compared an AI endoscopic cumulative disease score (CDS) to the Mayo endoscopic sco…
An AI scoring system matched ulcerative colitis symptoms better than standard endoscopy, helping doctors align what they see with how patien…
Apr 19, 2026
Neurology
Cohort
Neutrophil SIRL-1/IL-8 Ratio as a Diagnostic Biomarker for Inflammatory Bowel Disease
New Blood Ratio Could Spot IBD Faster
This single-center cohort study measured neutrophil SIRL-1 and serum IL-8 in 90 IBD patients and healthy volunteers.
A new blood ratio measuring two immune signals could help doctors diagnose Crohn's and Ulcerative Colitis faster and more accurately.
Frontiers
Apr 19, 2026
Oncology
Sys. Review
Narrative review examines ulcerative colitis and colorectal cancer risk
Review of ulcerative colitis and colorectal cancer links in patients
This narrative review synthesizes evidence on ulcerative colitis and colorectal cancer risk.
Ulcerative colitis patients face cancer risk driven by inflammation, but better disease control and modern treatments are lowering overall c…
Frontiers
Apr 17, 2026
Primary Care & Family Medicine
Cohort
Latent profiles of self-management behavior identified in Chinese ulcerative colitis patients
Chinese ulcerative colitis patients show varied self-management behaviors linked to social support and mood
This cross-sectional study of 415 Chinese patients with ulcerative colitis identified three self-management behavior profiles.
Chinese ulcerative colitis patients with strong social support and fewer mood issues actively manage their daily lives better than others.
Frontiers
Apr 17, 2026
Gastroenterology
Cohort
Cross-sectional data suggest IgG glycans discriminate inflammatory bowel disease from controls
A Simple Blood Test May Spot Crohn's and Colitis Early
This cross-sectional study analyzed 1,367 plasma samples from individuals with Crohn's disease or ulcerative colitis, healthy controls, and …
A simple blood test reveals a sugar pattern that spots inflammatory bowel disease early and shows how the illness quietly ages the body.
medRxiv
Apr 16, 2026
Drug Pipeline
RCT
Guselkumab showed improved clinical remission in refractory ulcerative colitis versus placebo
Guselkumab shows promise for ulcerative colitis in this early phase 3 trial
This phase 3 randomized trial evaluated guselkumab in adults with moderately to severely active ulcerative colitis who had inadequate respon…
Patients with ulcerative colitis who failed other treatments achieved remission in a new trial using subcutaneous guselkumab injections.
Apr 15, 2026
Pediatrics
Meta-analysis
Meta-analysis finds increased VTE risk in pediatric IBD, especially ulcerative colitis
Kids with Bowel Disease Face a Hidden Blood Clot Risk Adults Miss
A systematic review and meta-analysis of over 100,000 children and teenagers with IBD found a significantly increased risk of venous thrombo…
Children with Crohn's or ulcerative colitis face nearly seven times the blood clot risk of healthy kids, yet prevention guidelines for teens…
Apr 14, 2026
Gastroenterology
Single-cell sequencing reveals T cell clonal patterns in healthy donors and ulcerative colitis patients
T Cells Move Freely in Colon, Not Just in Blood
This observational study analyzed 333,088 T cells from healthy donors and ulcerative colitis (UC) patients using single-cell T cell receptor…
T cells in the colon travel freely across the gut, not just in the blood, reshaping how we understand immune health in conditions like ulcer…
medRxiv
Apr 14, 2026
OB/GYN & Women's Health
Meta-analysis
Meta-analysis of over 13 million births shows no association between Cesarean section and inflammatory bowel disease risk
Does having a C-section raise your child's risk of inflammatory bowel disease?
This systematic review and meta-analysis evaluated the association between mode of delivery and risk of inflammatory bowel disease (IBD) in …
A review of over 13 million births found no link between C-sections and inflammatory bowel disease, easing concerns for parents.
Frontiers
Apr 9, 2026
Rheumatology
Cohort
PRO and Serum Biomarker Models Predict Endoscopic Activity in Ulcerative Colitis
Count Your Stools to Spot Flare-Ups Early
A retrospective multicenter cohort study of 297 UC patients developed models using patient-reported outcomes (stool frequency, rectal bleedi…
Counting your daily stools and bleeding can accurately spot ulcerative colitis flare-ups without needing an invasive colonoscopy.
Frontiers
Apr 9, 2026
Rheumatology
RCT
Vedolizumab plus curcumin improves remission in moderate-to-severe ulcerative colitis versus vedolizumab alone
Could adding curcumin to your current ulcerative colitis treatment help you reach remission faster?
This multicenter, double-blind randomized controlled trial enrolled 159 patients with moderate-to-severe ulcerative colitis.
Adding curcumin to ulcerative colitis treatment helped more patients reach symptom remission faster than using standard drugs alone.
Frontiers
Apr 8, 2026