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Home › Conditions › Peripheral vascular disease

Peripheral vascular disease

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Peripheral vascular disease

42 trials tracked for Peripheral vascular disease: 5 in phase 3 or 4.

42Trials tracked
5Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 3 Phase 3 2 Phase 2 4 Other / NA 33
  1. Phase 4 Testosterone for Peripheral Vascular Disease Completed
  2. Phase 4 Vorapaxar on Thrombin Generation and Coagulability Completed
  3. Phase 4 Evaluation of Cilostazol in Combination With L-Carnitine Completed
  4. Phase 3 Trial to Evaluate the Safety & Efficacy of the Absolute Pro™ Peripheral Self-Expanding Stent System in Subjects With Atherosclerotic de Novo or Restenotic Lesions in the Native Common Iliac Artery and/or Native External Iliac Artery. Completed
  5. Phase 3 Trial to Evaluate the Safety & Efficacy of the Omnilink Elite™ Peripheral Balloon-Expandable Stent System in Subjects With Atherosclerotic de Novo or Restenotic Lesions in the Native Common Iliac Artery and/or Native External Iliac Artery Completed
  6. Phase 2 3 Month PHI PAD PoM Study Completed
Show 36 more trials
  1. Phase 2 Investigational Device Exemption Study to Determine the Safety and Efficacy of the Astron and Pulsar Stents Completed
  2. Phase 2 PF-00489791 For The Treatment Of Raynaud's Completed
  3. Phase 2 Study of Hepatocyte Growth Factor (HGF) Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia Patients With Peripheral Ischemic Ulcers Completed
  4. N/A JetStream (JS) Atherectomy in Femoropopliteal In-Stent Restenotic Lesions Completed
  5. N/A Registry of AngioJet Use in the Peripheral Vascular System Completed
  6. N/A Disrupt PAD+ Study With the Shockwave Medical M5+ Peripheral IVL System Completed
  7. N/A Effects of Paclitaxel on Intimal Hyperplasia Completed
  8. N/A Bard® LifeStent® Vascular Stent Delivery System Study Completed
  9. N/A Impedance Sensor Evaluated in Peripheral Artery Disease for Tissue Detection Completed
  10. N/A Safety and Efficacy of the SurVeil™ Drug-Coated Balloon Completed
  11. N/A JET-RANGER Trial - JETStream Atherectomy With Adjunctive Paclitaxel-Coated Balloon Angioplasty vs Plain Old Balloon Angioplasty Followed by Paclitaxel-Coated Balloon Completed
  12. N/A Study to Compare 2 Doses of Polycap Versus Single Dose of Polycap With or Without Pottasium Completed
  13. N/A The Evicel Post-Authorization Surveillance Study Completed
  14. N/A The Complete® SE SFA Study for the Treatment of SFA/PPA Lesions Completed
  15. N/A BARD® The VENOVO™ Venous Stent Study for Treatment of Iliofemoral Occlusive Disease Completed
  16. N/A A Multi-center Clinical Trial of the Misago™ Self-Expanding Stent System for Superficial Femoral Artery Completed
  17. N/A Effect of Nike FuelBand on Exercise and Function in Claudicants; a Randomised Controlled Trial Completed
  18. N/A Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2) Completed
  19. N/A The Complete® Self-Expanding Stent and Stent Delivery System Registry Completed
  20. N/A BARD® Study of LIFESTREAM™ Balloon Expandable Covered Stent Treating Iliac Arterial Occlusive Disease Completed
  21. N/A Tissue Removal Assessment With Ultrasound of THe SFA and Popliteal Completed
  22. N/A Atherectomy By Laser Ablation With Turbo-Elite Completed
  23. N/A Tele-Health Electronic Monitoring to Reduce Post Discharge Complications and Surgical Site Infections Completed
  24. N/A Project to Improve Communication About Serious Illness - Pilot Study Completed
  25. N/A Absolute Pro® MOMENTUM™ Completed
  26. N/A Zilver PTX Delivery System Completed
  27. N/A Adjuvant Benefit of NMES to Supervised Exercise in Patients With IC Completed
  28. N/A Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1) Completed
  29. N/A Comparison of the SUpera® PERipheral System in the Superficial Femoral Artery Completed
  30. N/A A Study on the Use of CorMatrix® ECM® for Femoral Arterial Reconstruction Completed
  31. N/A The ACTIVE (Use of the Assurant® Cobalt Iliac Stent System in the Treatment of Iliac Vessel Disease) Study Completed
  32. N/A Femoral Arterial Access With Ultrasound Trial Completed
  33. N/A ESPRIT I: A Clinical Evaluation of the Abbott Vascular ESPRIT BVS (Bioresorbable Vascular Scaffold) System Completed
  34. N/A Neuromuscular Electrical Stimulation (NMES) in Patients With Intermittent Claudication Completed
  35. N/A Guided Meditation to Decrease Perioperative Anxiety and Increase Patient Intraoperative Compliance in Vascular Surgery Completed
  36. N/A Atrium iCAST Iliac Stent Pivotal Study Completed

Showing the 42 most-cited and recently-updated of 42 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Peripheral vascular disease: what the trials found

Clinical evaluations of peripheral vascular interventions show varying outcomes for walking impairment. The Omnilink Elite™ Peripheral Balloon-Expandable Stent System was associated with Walking Impairment Questionnaire scores of 46.8, 41.8, and 55.4 6, while the Absolute Pro™ Peripheral Self-Expanding Stent System showed scores of 54.1, 49.2, and 58.9 7.

In pharmacological trials for peripheral conditions, cilostazol demonstrated a statistically significant improvement in Peak Walking Time (PWT) at 180 days with results of 0.267 and 0.145 (p=0.048) 5. Vorapaxar was evaluated regarding platelet aggregation induced by PAR-1 Activating Peptide, resulting in values of 8, 5, and 5 3.

Recent results — preliminary, needs further review

  • The Jumpstart Intervention showed a statistically significant difference in the documentation of goals of care (16 vs. 6; p=0.036) 12.
  • The Clotild Smart Guidewire System demonstrated an ability to differentiate various tissues in peripheral artery disease with results of 0.3782 and 0.0284 (p<=0.0001) 2.

For the clinician treating this condition

  • Stent systems such as Omnilink Elite™ and Absolute Pro™ are established for use in peripheral interventions, though specific walking impairment scores vary between devices.
  • Cilostazol is an established intervention showing significant improvement in peak walking time at 180 days.
  • The Jumpstart Intervention is a recently observed method to improve the documentation of goals of care.

AI synthesis of 6 cited trials, updated Jun 25, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
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