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Neurology
Meta-analysis
Obstetric CVST: 8.28% maternal mortality acutely, 3.17% recurrence in follow-up cohorts
Anticoagulants show mixed results for pregnant women with blood clots
This meta-analysis synthesizes outcomes across two distinct obstetric cerebral venous sinus thrombosis populations: acute CVST and women wit…
New data reveals that while some pregnant women with blood clots face high risks, others with known history show good delivery outcomes.
Frontiers
Sep 11, 2026
Cardiology
Meta-analysis
Adding antiplatelet therapy to anticoagulation does not cut stroke risk but raises major bleeding
Combined Anticoagulant and Antiplatelet Therapy Increases Bleeding Risk
This meta-analysis of 14,884 patients with recent ischemic stroke, nonvalvular atrial fibrillation, and large artery atherosclerosis found t…
Combining two types of blood thinners may increase bleeding risks without reducing the chance of a second stroke in patients with certain he…
Aug 26, 2026
Cardiology
Meta-analysis
Discontinuing oral anticoagulants after ablation lowers bleeding but raises stroke risk in high-risk patients
Stopping blood thinners after heart ablation may reduce bleeding risks
A meta-analysis of patients with atrial fibrillation after catheter ablation found that stopping oral anticoagulation was not associated wit…
New data shows that stopping blood thinners after a heart procedure can lower bleeding risks, but it may increase stroke risk for some patie…
Aug 1, 2026
Cardiology
Meta-analysis
Oral anticoagulant monotherapy significantly reduces major bleeding compared to combined therapy in stable coronary artery disease
Anticoagulant alone may cut bleeding risk in heart patients
This meta-analysis of randomized controlled trials involving 5924 patients found that oral anticoagulant monotherapy results in a comparable…
For some heart patients, skipping aspirin and using only an anticoagulant may lower bleeding risk without raising heart risks.
Aug 1, 2026
Neurology
Meta-analysis
Anticoagulation associated with lower risk of recurrent stroke in patients with left ventricular systolic dysfunction
Anticoagulants may lower stroke risk for patients with heart dysfunction
This meta-analysis of secondary analyses of randomized clinical trials examines anticoagulation for ischemic stroke prevention in patients w…
New analysis suggests that blood thinners might reduce the risk of both first and repeat strokes in people with specific types of heart musc…
Aug 1, 2026
Cardiology
Meta-analysis
Discontinuing oral anticoagulation after AF ablation reduces bleeding without increasing thromboembolic risk
Stopping blood thinners after heart rhythm repair cuts bleeding risk without raising stroke danger
This systematic review and meta-analysis evaluated patients who stopped versus continued oral anticoagulation following atrial fibrillation …
A massive analysis shows stopping blood thinners after heart rhythm repair cuts bleeding risk without raising stroke danger for many patient…
Jun 1, 2026
Cardiology
Guideline
Guideline case report on perioperative tamponade and protamine reaction in DeBakey type I aortic dissection repair
Rare allergy and blood pressure issues caused sudden heart arrest during aortic repair
This guideline presents a case report of a 63-year-old man undergoing staged TEVAR for DeBakey type I aortic dissection.
A rare allergic reaction combined with fluid buildup stopped a heart during complex aortic surgery, but doctors saved the patient with fast …
Frontiers
Apr 29, 2026
Oncology
Meta-analysis
Meta-analysis identifies prognostic factors for recurrent VTE and bleeding in 96 753 adult cancer patients
Certain cancer types and health factors raise risk of blood clots or bleeding in adults with cancer and VTE
This meta-analysis evaluated prognostic factors for recurrent venous thromboembolism (VTE) or anticoagulant-related bleeding in 96 753 adult…
A large review found that specific cancers and health factors significantly increase the risk of recurrent blood clots or bleeding in adults…
Apr 23, 2026
Cardiology
RCT
Shorter fibrin clot lysis time linked to higher bleeding risk in atrial fibrillation patients on anticoagulants
Short clot breakdown time predicts higher bleeding risk
This RCT in 1,841 atrial fibrillation patients found that shorter pretreatment fibrin clot lysis time was associated with a significantly hi…
A simple blood test measuring how fast clots dissolve could help doctors spot patients at higher risk of bleeding before they even start tak…
Apr 22, 2026
Cardiology
Meta-analysis
STEMI guidelines rely heavily on moderate and low-quality evidence, meta-analysis finds
Most heart attack guidelines rely on weak evidence, not strong proof
A meta-analysis of 26 STEMI guidelines (2,139 recommendations) from 1990-2023 found that 30.1% of recommendations were based on moderate-qua…
Most heart attack treatment rules are based on weak evidence, not strong proof, leaving doctors flying blind on critical care decisions.
Apr 9, 2026
Hematology
RCT
Direct pressure for 5 minutes reduces ecchymosis after venipuncture in older anticoagulated patients
How long should you press after a blood draw to prevent bruising in older adults?
A randomized controlled trial of 164 older hospitalized patients on anticoagulants found that applying 20 N of direct pressure for 5 minutes…
Holding pressure for five minutes after a blood draw significantly reduces painful bruises in older adults taking blood thinners compared to…
Apr 7, 2026