Meta-analysis shows no significant difference between immediate and staged revascularization for STEMI with multivessel disease
Immediate heart procedure shows no major benefit over staged approach for heart attack patients
This systematic review and meta-analysis evaluated patients with ST-elevation myocardial infarction and multivessel disease undergoing immed…
A large review of heart attack patients with multiple blocked arteries found that doing the full procedure right away did not lower the risk…
Family history, prior arrhythmia, and anterior infarct location independently raise risk of ventricular fibrillation in STEMI patients
Family history and heart attack location raise risk of dangerous heart rhythms in young patients
This meta-analysis of 1807 cases and 2923 controls confirms that family history of sudden death, previous atrial fibrillation, and anterior …
A large study found that family history of sudden death, past atrial fibrillation, and front heart attacks increase the chance of dangerous …
Rescue PCI after failed fibrinolysis linked to worse outcomes in STEMI compared to scheduled angiography
Rescue PCI after failed clot-busting drugs caused worse heart outcomes than planned angiography
This pre-specified analysis of the STREAM-2 RCT compared rescue PCI after failed fibrinolysis with scheduled angiography in 583 patients wit…
Patients needing emergency heart catheterization after clot-busting drugs fared worse than those who received planned procedures, with highe…
In STEMI patients, admission CK-MB and CPK elevation predicts adverse outcomes in a small cross-sectional study
Old Heart Tests Still Save Lives
This cross-sectional study evaluated 15 patients with ST-elevation myocardial infarction (STEMI) at the Punjab Institute of Cardiology, Laho…
Imagine waking up with crushing chest pain.
STEMI guidelines rely heavily on moderate and low-quality evidence, meta-analysis finds
Most heart attack guidelines rely on weak evidence, not strong proof
A meta-analysis of 26 STEMI guidelines (2,139 recommendations) from 1990-2023 found that 30.1% of recommendations were based on moderate-qua…
Most heart attack treatment rules are based on weak evidence, not strong proof, leaving doctors flying blind on critical care decisions.
CTO PCI does not affect diastolic coupling in STEMI patients; elevated baseline LACI predicts mortality
Does opening a blocked artery after a heart attack help the heart relax?
In this RCT of 200 STEMI patients with concurrent CTO, CTO PCI did not significantly affect left atrioventricular coupling index (LACI) at 4…
Opening a blocked artery after a heart attack doesn't help the heart relax, but early heart relaxation scores predict who is most at risk of…
Research across Myocardial ischemia
Related studies from across the Myocardial ischemia family.
Individualized six-phase antithrombotic strategy leads to left ventricular thrombus resolution and neurological recovery
New strategy helps manage heart blood clots after heart attack
This case report describes an individualized six-phase antithrombotic strategy for a 27-year-old male with myocardial infarction, stroke, hy…
A tailored six-phase treatment plan helped a young man recover fully from a stroke and heart attack while successfully clearing dangerous bl…
Current literature lacks research on myocardial infarction warning signs within transgender and gender diverse populations in the United States
No clear guide exists for transgender heart attack warning signs in the United States
A brief review highlights a critical gap in understanding heart attack symptoms for transgender and gender diverse individuals. More researc…
A review found no current research on heart attack warning signs for transgender people, leaving them without standard heart health educatio…
Polygenic scores link to atherosclerosis and ischemic heart disease in Russian populations
Genetic markers help predict heart disease risk for Russian men and women
This meta-analysis review examines genetic predictors of atherosclerosis, ischemic heart disease, and myocardial infarction in a Russian pop…
A large study found specific genes linked to cholesterol levels in Russian people. These genetic scores can help doctors check heart disease…
Staged revascularization shows no significant difference versus immediate revascularization for major adverse cardiovascular events in STEMI and MVD patients
Timing of heart surgery does not change survival for a specific heart attack group
This meta-analysis reviewed 5077 patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease comparing …
A large review found that waiting for staged heart surgery did not improve survival or reduce heart attacks compared to immediate surgery fo…
Baduanjin exercise practice improves outcomes for patients with acute myocardial infarction undergoing percutaneous coronary intervention procedures
Baduanjin exercise improves heart recovery and mood after heart attack surgery
A systematic review and meta-analysis of 1,293 patients with acute myocardial infarction undergoing percutaneous coronary intervention found…
A meta-analysis shows Baduanjin exercise improved heart function, walking distance, and mood in patients recovering from heart attacks and s…
Complete revascularization shows high probability of benefit for NSTEMI patients with multivessel disease
Complete revascularization shows high probability of benefit for NSTEMI patients with multivessel disease
This Bayesian re-analysis of a randomized trial evaluated complete versus culprit-only revascularization in patients with non-ST-elevation m…
A Bayesian re-analysis suggests complete revascularization offers a high probability of clinically meaningful benefit compared to treating o…
Docetaxel chemotherapy is highly suspect for causing acute myocardial infarction in a low-risk triple-negative breast cancer patient
Docetaxel chemotherapy linked to rare heart attack in breast cancer patient
This case report and literature review examines acute myocardial infarction following docetaxel chemotherapy in a patient with triple-negati…
A rare heart attack occurred after docetaxel chemotherapy in a patient with triple-negative breast cancer. This case review suggests the dru…
Serum resistin levels rise progressively with worsening severity of coronary heart disease and acute myocardial infarction in this meta-analysis
High blood resistin levels linked to heart disease severity in large analysis
A network meta-analysis of 9,169 subjects reveals that serum resistin levels increase stepwise as coronary heart disease severity worsens. W…
A large network meta-analysis found that higher serum resistin levels are linked to worse coronary heart disease and acute heart attacks.
Review of immunomodulatory strategies for myocardial infarction notes major translational gaps and undefined heart-immune axis
New ideas for heart attack treatment face big scientific hurdles
This review examines immunomodulatory strategies targeting the CCR2/CCL2 axis, regulatory T cells, and macrophage polarization compared to c…
Experts review new immune-targeting strategies for heart attacks but note major gaps in understanding how the heart and immune system intera…
Breast arterial calcification linked to increased cardiovascular mortality risk
Calcified breast arteries linked to higher risk of heart disease and death
This meta-analysis examined associations between breast arterial calcification and cardiovascular outcomes. The authors observed that the pr…
A large analysis shows breast arterial calcification is associated with higher risks of heart failure, stroke, and death in women.
Network meta-analysis of oral Chinese patent medicines for myocardial infarction with heart failure
Four Chinese medicines show promise for heart failure after heart attack
This network meta-analysis evaluated oral Chinese patent medicines combined with conventional treatment in patients with myocardial infarcti…
A network meta-analysis of 42 trials found four oral Chinese patent medicines improved outcomes when added to standard heart failure treatme…
Prehospital unfractionated heparin bolus improved TIMI flow in STEMI without increasing bleeding risk
Pretreatment with UFH improves artery flow for STEMI patients without extra bleeding risk
This single-center randomized trial evaluated pretreatment with unfractionated heparin in patients with ST-segment-elevation myocardial infa…
Giving unfractionated heparin early at first medical contact improved artery flow in heart attack patients without increasing bleeding risk.
Questions about ST-Elevation Myocardial Infarction
Does having a family history of sudden death make ventricular fibrillation more likely in STEMI?
Yes, a family history of sudden death independently raises the odds of ventricular fibrillation during a first STEMI by about 60%, according to a large meta-analysis.
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