Ticagrelor reduces mortality and major adverse cardiovascular events compared to clopidogrel in STEMI patients
Ticagrelor Shows Lower Mortality Risk Than Clopidogrel for Heart Patients
This meta-analysis of 31,729 adult STEMI patients post-PCI found that ticagrelor significantly reduced all-cause mortality (OR = 0.64) and m…
A large analysis of over 31,000 patients suggests ticagrelor may lower mortality and heart attack risks compared to clopidogrel after a hear…
Transvalvular microaxial flow pump plus PCI does not reduce infarct size in anterior STEMI
Trial shows microaxial flow pump does not reduce heart damage
This randomized controlled trial of 527 adults with acute anterior STEMI found that LV unloading with a transvalvular microaxial flow pump f…
A clinical trial found that using a transvalvular microaxial flow pump before heart surgery did not reduce the size of heart tissue damage.
Staged revascularization shows no significant difference versus immediate revascularization for major adverse cardiovascular events in STEMI and MVD patients
Timing of heart surgery does not change survival for a specific heart attack group
This meta-analysis reviewed 5077 patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease comparing …
A large review found that waiting for staged heart surgery did not improve survival or reduce heart attacks compared to immediate surgery fo…
Prehospital unfractionated heparin bolus improved TIMI flow in STEMI without increasing bleeding risk
Pretreatment with UFH improves artery flow for STEMI patients without extra bleeding risk
This single-center randomized trial evaluated pretreatment with unfractionated heparin in patients with ST-segment-elevation myocardial infa…
Giving unfractionated heparin early at first medical contact improved artery flow in heart attack patients without increasing bleeding risk.
Intracoronary nicorandil improves TIMI flow and reduces AMR in STEMI patients undergoing primary PCI
New Drug Opens Tiny Vessels After Heart Attack Treatment
This single-center randomized trial enrolled 63 patients with first-episode ST-segment elevation myocardial infarction undergoing primary PC…
A new drug given during heart surgery may help blood flow reach the heart muscle better.
Atorvastatin dose and PCI timing predict hypoperfusion in STEMI patients
New Tool Predicts Heart Damage Risk After Emergency Stent Procedure
This cohort study evaluated 434 patients with acute ST-segment elevation myocardial infarction (STEMI) who underwent primary PCI.
This new tool could help doctors identify high-risk heart attack patients sooner, potentially improving survival and recovery rates.
Residual global μQFR assessment associated with 3-year MACE risk in acute coronary syndrome patients
Better Heart Maps Predict Long-Term Survival
This post hoc analysis of a randomized controlled trial evaluated 2,428 acute coronary syndrome patients over 36.0 months.
A new heart map predicts long-term survival just as well as expensive pressure wires, helping doctors spot high-risk patients after stent pr…
Predictive model for acute heart failure in STEMI patients after PCI shows high accuracy
New Score Predicts Heart Failure Risk After Heart Attack
A retrospective cohort study of 419 STEMI patients treated with PCI at Maanshan People's Hospital evaluated a predictive model for acute hea…
A new score predicts heart failure risk after heart attack by using blood pressure and lab results to spot danger before symptoms appear.
STEMI guidelines rely heavily on moderate and low-quality evidence, meta-analysis finds
Most heart attack guidelines rely on weak evidence, not strong proof
A meta-analysis of 26 STEMI guidelines (2,139 recommendations) from 1990-2023 found that 30.1% of recommendations were based on moderate-qua…
Most heart attack treatment rules are based on weak evidence, not strong proof, leaving doctors flying blind on critical care decisions.
CT-detected subclinical pulmonary congestion associated with in-hospital MACE in Killip class 1 STEMI
CT lung water measures predict heart attack risks in hospital
A retrospective cohort of 249 Killip class 1 STEMI patients found that higher CT-assessed extravascular lung water (EVLW) was associated wit…
Hidden fluid in the lungs seen on CT scans signals a higher risk of serious heart events for patients with heart attacks.
Retrospective study identifies five predictors for hypokalemia in STEMI patients
Can a simple checklist predict dangerous potassium drops after a major heart attack?
A retrospective observational cohort study of 320 STEMI patients at a single Chinese hospital identified five independent predictors for hyp…
A new checklist using five simple signs can predict dangerous potassium drops that trigger deadly heart rhythms after a major heart attack.
Phase 2 trial tests pre-hospital glucocorticoid pulse in STEMI patients undergoing primary PCI
Phase 2 trial tests steroid pulse for heart attack patients before hospital arrival
A phase 2 randomized controlled trial enrolled 530 STEMI patients treated with primary PCI to test single-dose glucocorticoid pulse therapy …
A new trial tested giving a single steroid dose in ambulances before heart attack patients reach the hospital to reduce permanent heart dama…
Research across Myocardial ischemia
Related studies from across the Myocardial ischemia family.
SGLT2 inhibitors and GLP-1 receptor agonists show similar MACE reduction in type 2 diabetes
Trial shows similar heart benefits for two diabetes medications
This systematic review and network meta-analysis compared SGLT2 inhibitors and GLP-1 receptor agonists for major adverse cardiovascular even…
Two common types of diabetes drugs both show significant reductions in major heart events for patients with a history of heart attacks.
Behavioral and metabolic factors characterize a distinct premature atherosclerosis phenotype in Chinese patients
Smoking and Metabolic Factors Linked to Heart Attacks in China
This systematic review of 317 observational studies maps risk factors for premature myocardial infarction (PMI) in China. The synthesis iden…
A large review of 317 studies identifies specific behavioral and metabolic risk factors for heart attacks among Chinese patients.
Percutaneous transcatheter closure using an Amplatzer Muscular VSD Occluder treats left ventricular pseudoaneurysm
Transcatheter Closure Shows Promise for Heart Failure Patients
This case report describes a 75-year-old male with heart failure and a left ventricular pseudoaneurysm successfully treated via percutaneous…
A new procedure using a transcatheter occluder may offer a safe way to treat heart failure caused by a specific heart wall defect.
Magnetocardiography identifies infarction features in MINOCA patients with normal ECG findings
Magnetocardiography shows heart damage when standard tests are normal
This case series explores the use of magnetocardiography (MCG) for identifying myocardial infarction in patients with non-ST-segment elevati…
New imaging may help identify heart attacks in patients whose standard EKG results appear normal, offering a potential new tool for clearer …
21% hypertension prevalence in transgender adults: meta-analysis of cardiovascular morbidities
Transgender adults face high rates of heart disease
This meta-analysis of observational studies reports pooled prevalence of major cardiovascular morbidities among transgender adults aged ≥18 …
One in five transgender adults has high blood pressure, and many have heart disease, a new analysis finds.
Macrophage migration inhibitory factor serves as a potential biomarker and therapeutic target for atrial fibrillation
Protein levels may predict heart failure and stroke risks
This systematic review synthesizes evidence regarding macrophage migration inhibitory factor (MIF) in the context of atrial fibrillation and…
A specific protein called MIF is linked to heart damage and can help doctors predict serious complications like stroke or heart failure.
Finerenone reduces mortality and heart failure risk (HR 0.644) in post-AMI patients
Finerenone may lower heart failure risk after heart attack
This retrospective cohort study of 1,012 adult patients with AMI found that finerenone initiation within 6 months was associated with a lowe…
A new look at real-world data suggests the drug finerenone could protect hearts and kidneys in patients following a heart attack.
Immune-stromal imbalance drives heart failure after myocardial infarction, systematic review finds
Immune cell balance determines if heart tissue heals or fails
This systematic review maps the bidirectional regulatory network between immune cells and cardiac stromal cells after myocardial infarction.…
A new map of how immune cells talk to heart tissue helps explain why some hearts heal after a heart attack while others develop failure.
Tocilizumab shows early anti-inflammatory effects but no significant clinical benefit in STEMI or NSTEMI
Tocilizumab shows early signs of heart protection in heart attacks
This meta-analysis of randomized controlled trials evaluated tocilizumab for patients with STEMI and NSTEMI. While the intervention showed a…
A new review looks at how the drug tocilizumab affects patients with heart attacks, showing some early signs of reduced inflammation.
Individualized six-phase antithrombotic strategy leads to left ventricular thrombus resolution and neurological recovery
New strategy helps manage heart blood clots after heart attack
This case report describes an individualized six-phase antithrombotic strategy for a 27-year-old male with myocardial infarction, stroke, hy…
A tailored six-phase treatment plan helped a young man recover fully from a stroke and heart attack while successfully clearing dangerous bl…
SGLT2 inhibitors provide robust prognostic benefits in heart failure with inconsistent results in post-myocardial infarction settings
SGLT2 inhibitors show promise for heart failure and diabetes
This narrative review examines the cardiovascular and metabolic effects of SGLT2 inhibitors, specifically empagliflozin and dapagliflozin. T…
New evidence shows how SGLT2 inhibitors may protect the heart and manage risks for patients with type 2 diabetes and heart failure.
Current literature lacks research on myocardial infarction warning signs within transgender and gender diverse populations in the United States
No clear guide exists for transgender heart attack warning signs in the United States
A brief review highlights a critical gap in understanding heart attack symptoms for transgender and gender diverse individuals. More researc…
A review found no current research on heart attack warning signs for transgender people, leaving them without standard heart health educatio…
Questions about ST-Segment Elevation Myocardial Infarction
Are many current STEMI treatment guidelines based on strong scientific evidence?
No, many current STEMI treatment guidelines are based on moderate or low-quality evidence, with only a small fraction supported by high-level studies.
Full answer →Can a CT scan show hidden lung water that predicts bad outcomes in STEMI?
Yes, a CT scan can detect hidden lung water (extravascular lung water) in STEMI patients, and this finding is linked to a higher risk of in-hospital major adverse cardiovascular events.
Full answer →How accurate is the new model for predicting heart failure after STEMI surgery?
A new model predicts acute heart failure after STEMI PCI with 82.4% accuracy, 74% sensitivity, and 86.8% specificity, outperforming older scores.
Full answer →Does the timing of my heart surgery affect how well blood flows in STEMI?
Yes, timing matters: longer delays from symptom onset to PCI are linked to worse blood flow and outcomes in STEMI.
Full answer →Can taking nicorandil during heart surgery improve blood flow for STEMI patients?
Yes, a 2024 trial found that giving intracoronary nicorandil during primary PCI improves blood flow (TIMI grade) and reduces microvascular resistance in STEMI patients.
Full answer →All ST-Segment Elevation Myocardial Infarction Articles
- Ticagrelor reduces mortality and major adverse cardiovascular events compared to clopidogrel in STEMI patients
- Transvalvular microaxial flow pump plus PCI does not reduce infarct size in anterior STEMI
- Staged revascularization shows no significant difference versus immediate revascularization for major adverse cardiovascular events in STEMI and MVD patients
- Prehospital unfractionated heparin bolus improved TIMI flow in STEMI without increasing bleeding risk
- Intracoronary nicorandil improves TIMI flow and reduces AMR in STEMI patients undergoing primary PCI
- Atorvastatin dose and PCI timing predict hypoperfusion in STEMI patients
- Predictive model for acute heart failure in STEMI patients after PCI shows high accuracy
- Residual global μQFR assessment associated with 3-year MACE risk in acute coronary syndrome patients
- CT-detected subclinical pulmonary congestion associated with in-hospital MACE in Killip class 1 STEMI
- STEMI guidelines rely heavily on moderate and low-quality evidence, meta-analysis finds
- Retrospective study identifies five predictors for hypokalemia in STEMI patients
- Phase 2 trial tests pre-hospital glucocorticoid pulse in STEMI patients undergoing primary PCI
- Immediate revascularization tied to higher 1-year risk in STEMI with multivessel disease and heart failure