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Cardiology
Cohort
Intracoronary nicorandil improves TIMI flow and reduces AMR in STEMI patients undergoing primary PCI
New Drug Opens Tiny Vessels After Heart Attack Treatment
This single-center randomized trial enrolled 63 patients with first-episode ST-segment elevation myocardial infarction undergoing primary PC…
A new drug given during heart surgery may help blood flow reach the heart muscle better.
Frontiers
Apr 22, 2026
Cardiology
Cohort
Atorvastatin dose and PCI timing predict hypoperfusion in STEMI patients
New Tool Predicts Heart Damage Risk After Emergency Stent Procedure
This cohort study evaluated 434 patients with acute ST-segment elevation myocardial infarction (STEMI) who underwent primary PCI. Independen…
This new tool could help doctors identify high-risk heart attack patients sooner, potentially improving survival and recovery rates.
Frontiers
Apr 21, 2026
Cardiology
RCT
Residual global μQFR assessment associated with 3-year MACE risk in acute coronary syndrome patients
Better Heart Maps Predict Long-Term Survival
This post hoc analysis of a randomized controlled trial evaluated 2,428 acute coronary syndrome patients over 36.0 months. High-risk residua…
A new heart map predicts long-term survival just as well as expensive pressure wires, helping doctors spot high-risk patients after stent pr…
Apr 16, 2026
Cardiology
Cohort
Predictive model for acute heart failure in STEMI patients after PCI shows high accuracy
New Score Predicts Heart Failure Risk After Heart Attack
A retrospective cohort study of 419 STEMI patients treated with PCI at Maanshan People's Hospital evaluated a predictive model for acute hea…
A new score predicts heart failure risk after heart attack by using blood pressure and lab results to spot danger before symptoms appear.
Frontiers
Apr 16, 2026
Cardiology
Meta-analysis
STEMI guidelines rely heavily on moderate and low-quality evidence, meta-analysis finds
Most heart attack guidelines rely on weak evidence, not strong proof.
A meta-analysis of 26 STEMI guidelines (2,139 recommendations) from 1990-2023 found that 30.1% of recommendations were based on moderate-qua…
Most heart attack treatment rules are based on weak evidence, not strong proof, leaving doctors flying blind on critical care decisions.
Apr 9, 2026
Cardiology
Cohort
CT-detected subclinical pulmonary congestion associated with in-hospital MACE in Killip class 1 STEMI
CT lung water measures predict heart attack risks in hospital
A retrospective cohort of 249 Killip class 1 STEMI patients found that higher CT-assessed extravascular lung water (EVLW) was associated wit…
Hidden fluid in the lungs seen on CT scans signals a higher risk of serious heart events for patients with heart attacks.
Frontiers
Apr 9, 2026
Cardiology
Phase II
Phase 2 trial tests pre-hospital glucocorticoid pulse in STEMI patients undergoing primary PCI
Phase 2 trial tests steroid pulse for heart attack patients before hospital arrival
A phase 2 randomized controlled trial enrolled 530 STEMI patients treated with primary PCI to test single-dose glucocorticoid pulse therapy …
A new trial tested giving a single steroid dose in ambulances before heart attack patients reach the hospital to reduce permanent heart dama…
CT.gov
Mar 30, 2026
Cardiology
RCT
Immediate revascularization tied to higher 1-year risk in STEMI with multivessel disease and heart failure
For heart attack patients with heart failure, does fixing all blockages right away help or hurt?
In the OPTION-STEMI trial, immediate complete revascularization was not non-inferior to staged revascularization. A subgroup analysis found …
For heart attack patients with heart failure, fixing all blockages immediately raises the risk of death or another heart attack within a yea…
Mar 30, 2026