Staged revascularization shows no significant difference versus immediate revascularization for major adverse cardiovascular events in STEMI and MVD patients
Timing of heart surgery does not change survival for a specific heart attack group
This meta-analysis reviewed 5077 patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease comparing …
A large review found that waiting for staged heart surgery did not improve survival or reduce heart attacks compared to immediate surgery fo…
Prehospital unfractionated heparin bolus improved TIMI flow in STEMI without increasing bleeding risk
Pretreatment with UFH improves artery flow for STEMI patients without extra bleeding risk
This single-center randomized trial evaluated pretreatment with unfractionated heparin in patients with ST-segment-elevation myocardial infa…
Giving unfractionated heparin early at first medical contact improved artery flow in heart attack patients without increasing bleeding risk.
Intracoronary nicorandil improves TIMI flow and reduces AMR in STEMI patients undergoing primary PCI
New Drug Opens Tiny Vessels After Heart Attack Treatment
This single-center randomized trial enrolled 63 patients with first-episode ST-segment elevation myocardial infarction undergoing primary PC…
A new drug given during heart surgery may help blood flow reach the heart muscle better.
Atorvastatin dose and PCI timing predict hypoperfusion in STEMI patients
New Tool Predicts Heart Damage Risk After Emergency Stent Procedure
This cohort study evaluated 434 patients with acute ST-segment elevation myocardial infarction (STEMI) who underwent primary PCI.
This new tool could help doctors identify high-risk heart attack patients sooner, potentially improving survival and recovery rates.
Residual global μQFR assessment associated with 3-year MACE risk in acute coronary syndrome patients
Better Heart Maps Predict Long-Term Survival
This post hoc analysis of a randomized controlled trial evaluated 2,428 acute coronary syndrome patients over 36.0 months.
A new heart map predicts long-term survival just as well as expensive pressure wires, helping doctors spot high-risk patients after stent pr…
Predictive model for acute heart failure in STEMI patients after PCI shows high accuracy
New Score Predicts Heart Failure Risk After Heart Attack
A retrospective cohort study of 419 STEMI patients treated with PCI at Maanshan People's Hospital evaluated a predictive model for acute hea…
A new score predicts heart failure risk after heart attack by using blood pressure and lab results to spot danger before symptoms appear.
STEMI guidelines rely heavily on moderate and low-quality evidence, meta-analysis finds
Most heart attack guidelines rely on weak evidence, not strong proof
A meta-analysis of 26 STEMI guidelines (2,139 recommendations) from 1990-2023 found that 30.1% of recommendations were based on moderate-qua…
Most heart attack treatment rules are based on weak evidence, not strong proof, leaving doctors flying blind on critical care decisions.
CT-detected subclinical pulmonary congestion associated with in-hospital MACE in Killip class 1 STEMI
CT lung water measures predict heart attack risks in hospital
A retrospective cohort of 249 Killip class 1 STEMI patients found that higher CT-assessed extravascular lung water (EVLW) was associated wit…
Hidden fluid in the lungs seen on CT scans signals a higher risk of serious heart events for patients with heart attacks.
Retrospective study identifies five predictors for hypokalemia in STEMI patients
Can a simple checklist predict dangerous potassium drops after a major heart attack?
A retrospective observational cohort study of 320 STEMI patients at a single Chinese hospital identified five independent predictors for hyp…
A new checklist using five simple signs can predict dangerous potassium drops that trigger deadly heart rhythms after a major heart attack.
Phase 2 trial tests pre-hospital glucocorticoid pulse in STEMI patients undergoing primary PCI
Phase 2 trial tests steroid pulse for heart attack patients before hospital arrival
A phase 2 randomized controlled trial enrolled 530 STEMI patients treated with primary PCI to test single-dose glucocorticoid pulse therapy …
A new trial tested giving a single steroid dose in ambulances before heart attack patients reach the hospital to reduce permanent heart dama…
Immediate revascularization tied to higher 1-year risk in STEMI with multivessel disease and heart failure
For heart attack patients with heart failure, does fixing all blockages right away help or hurt?
In the OPTION-STEMI trial, immediate complete revascularization was not non-inferior to staged revascularization.
For heart attack patients with heart failure, fixing all blockages immediately raises the risk of death or another heart attack within a yea…
Research across Myocardial ischemia
Related studies from across the Myocardial ischemia family.
Individualized six-phase antithrombotic strategy leads to left ventricular thrombus resolution and neurological recovery
New strategy helps manage heart blood clots after heart attack
This case report describes an individualized six-phase antithrombotic strategy for a 27-year-old male with myocardial infarction, stroke, hy…
A tailored six-phase treatment plan helped a young man recover fully from a stroke and heart attack while successfully clearing dangerous bl…
Current literature lacks research on myocardial infarction warning signs within transgender and gender diverse populations in the United States
No clear guide exists for transgender heart attack warning signs in the United States
A brief review highlights a critical gap in understanding heart attack symptoms for transgender and gender diverse individuals. More researc…
A review found no current research on heart attack warning signs for transgender people, leaving them without standard heart health educatio…
Polygenic scores link to atherosclerosis and ischemic heart disease in Russian populations
Genetic markers help predict heart disease risk for Russian men and women
This meta-analysis review examines genetic predictors of atherosclerosis, ischemic heart disease, and myocardial infarction in a Russian pop…
A large study found specific genes linked to cholesterol levels in Russian people. These genetic scores can help doctors check heart disease…
Baduanjin exercise practice improves outcomes for patients with acute myocardial infarction undergoing percutaneous coronary intervention procedures
Baduanjin exercise improves heart recovery and mood after heart attack surgery
A systematic review and meta-analysis of 1,293 patients with acute myocardial infarction undergoing percutaneous coronary intervention found…
A meta-analysis shows Baduanjin exercise improved heart function, walking distance, and mood in patients recovering from heart attacks and s…
Complete revascularization shows high probability of benefit for NSTEMI patients with multivessel disease
Complete revascularization shows high probability of benefit for NSTEMI patients with multivessel disease
This Bayesian re-analysis of a randomized trial evaluated complete versus culprit-only revascularization in patients with non-ST-elevation m…
A Bayesian re-analysis suggests complete revascularization offers a high probability of clinically meaningful benefit compared to treating o…
Docetaxel chemotherapy is highly suspect for causing acute myocardial infarction in a low-risk triple-negative breast cancer patient
Docetaxel chemotherapy linked to rare heart attack in breast cancer patient
This case report and literature review examines acute myocardial infarction following docetaxel chemotherapy in a patient with triple-negati…
A rare heart attack occurred after docetaxel chemotherapy in a patient with triple-negative breast cancer. This case review suggests the dru…
Serum resistin levels rise progressively with worsening severity of coronary heart disease and acute myocardial infarction in this meta-analysis
High blood resistin levels linked to heart disease severity in large analysis
A network meta-analysis of 9,169 subjects reveals that serum resistin levels increase stepwise as coronary heart disease severity worsens. W…
A large network meta-analysis found that higher serum resistin levels are linked to worse coronary heart disease and acute heart attacks.
Review of immunomodulatory strategies for myocardial infarction notes major translational gaps and undefined heart-immune axis
New ideas for heart attack treatment face big scientific hurdles
This review examines immunomodulatory strategies targeting the CCR2/CCL2 axis, regulatory T cells, and macrophage polarization compared to c…
Experts review new immune-targeting strategies for heart attacks but note major gaps in understanding how the heart and immune system intera…
Breast arterial calcification linked to increased cardiovascular mortality risk
Calcified breast arteries linked to higher risk of heart disease and death
This meta-analysis examined associations between breast arterial calcification and cardiovascular outcomes. The authors observed that the pr…
A large analysis shows breast arterial calcification is associated with higher risks of heart failure, stroke, and death in women.
Network meta-analysis of oral Chinese patent medicines for myocardial infarction with heart failure
Four Chinese medicines show promise for heart failure after heart attack
This network meta-analysis evaluated oral Chinese patent medicines combined with conventional treatment in patients with myocardial infarcti…
A network meta-analysis of 42 trials found four oral Chinese patent medicines improved outcomes when added to standard heart failure treatme…
Case report and review of literature on acute NSTEMI after fluorescein angiography in a 76-year-old woman
Rare heart attack possible after fluorescein angiography in older adults with heart disease
This case report and review of the literature describes a 76-year-old woman with hypertension, hyperlipidemia, and type 2 diabetes mellitus …
A 76-year-old woman with heart disease had a heart attack shortly after a dye test, highlighting rare risks.
Meta-analysis shows no significant difference between immediate and staged revascularization for STEMI with multivessel disease
Immediate heart procedure shows no major benefit over staged approach for heart attack patients
This systematic review and meta-analysis evaluated patients with ST-elevation myocardial infarction and multivessel disease undergoing immed…
A large review of heart attack patients with multiple blocked arteries found that doing the full procedure right away did not lower the risk…
Questions about ST-Segment Elevation Myocardial Infarction
Are many current STEMI treatment guidelines based on strong scientific evidence?
No, many current STEMI treatment guidelines are based on moderate or low-quality evidence, with only a small fraction supported by high-level studies.
Full answer →Can a CT scan show hidden lung water that predicts bad outcomes in STEMI?
Yes, a CT scan can detect hidden lung water (extravascular lung water) in STEMI patients, and this finding is linked to a higher risk of in-hospital major adverse cardiovascular events.
Full answer →How accurate is the new model for predicting heart failure after STEMI surgery?
A new model predicts acute heart failure after STEMI PCI with 82.4% accuracy, 74% sensitivity, and 86.8% specificity, outperforming older scores.
Full answer →Does the timing of my heart surgery affect how well blood flows in STEMI?
Yes, timing matters: longer delays from symptom onset to PCI are linked to worse blood flow and outcomes in STEMI.
Full answer →Can taking nicorandil during heart surgery improve blood flow for STEMI patients?
Yes, a 2024 trial found that giving intracoronary nicorandil during primary PCI improves blood flow (TIMI grade) and reduces microvascular resistance in STEMI patients.
Full answer →