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Left Ventricular Systolic Dysfunction

Part of Ventricular Dysfunction

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Left Ventricular Systolic Dysfunction

4 trials tracked for Left Ventricular Systolic Dysfunction: 1 in phase 3 or 4 and 1 with published results. The most-cited published study has 42 citations.

4Trials tracked
1Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 1 Phase 2 1 Other / NA 2
  1. Phase 3 Ertugliflozin for Functional Mitral Regurgitation Completed · 42 cited
  2. Phase 2 COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure Completed
  3. N/A Sleep-Disordered Breathing in Heart Failure - The SchlaHF-Registry Completed
  4. N/A Heart Rate Response to Regadenoson and Sudden Cardiac Death Completed

Showing the 4 most-cited and recently-updated of 4 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Ventricular Dysfunction

Related studies from across the Ventricular Dysfunction family.

Elective unloading with a microaxial flow pump showed no material difference in outcomes versus standard care in severe left ventricular dysfunction
Cardiology RCT
Elective unloading with a microaxial flow pump showed no material difference in outcomes versus standard care in severe left ventricular dysfunction Heart Pump Strategy Backfires for Weakened Hearts During High-Risk Surgery
This randomized controlled trial enrolled 300 patients with severe left ventricular dysfunction and extensive coronary artery disease underg…
A heart pump meant to protect weakened hearts during surgery may increase death risk for patients with severe heart damage, new evidence sug…
Transendocardial ProtheraCytes injections improved physical functioning and vitality in patients with recent large AMI and LV dysfunction
Cardiology RCT
Transendocardial ProtheraCytes injections improved physical functioning and vitality in patients with recent large AMI and LV dysfunction New cell injections help heart patients feel better for six months
This phase I/IIb randomized controlled trial enrolled 31 treated and 12 control patients with recent large myocardial infarction and left ve…
Patients with recent heart attacks and weak heart pumps felt significantly better physically and socially after receiving new cell injection…
Non-randomized preprint on dapagliflozin and epicardial adipose tissue in HFpEF
Cardiology
Non-randomized preprint on dapagliflozin and epicardial adipose tissue in HFpEF Dapagliflozin linked to fat loss in heart failure patients
This preprint reports a non-randomized clinical trial in 60 patients with left ventricular diastolic dysfunction.
Adding dapagliflozin to standard care reduced epicardial fat in a small group of heart failure patients, though this preprint study needs co…
Diastolic Age predicts MACE and discriminates LVDD in heart failure cohorts
Cardiology Cohort
Diastolic Age predicts MACE and discriminates LVDD in heart failure cohorts Doctors Can Now Measure Your Heart’s True Age With One Scan
This cohort study involving 1,952 participants from the Project Baseline Health Study, 1,708 from WASE, and 313 from Stanford Cardiovascular…
A new scan tool calculates your heart's biological age to spot hidden risks before symptoms appear, though it is still experimental.