Prenatal exposure to certain psychotropic medications is associated with increased risk of gestational diabetes
Prenatal exposure to certain psychiatric drugs linked to gestational diabetes
This meta-analysis examined the relationship between prenatal exposure to antipsychotics and antidepressants and the risk of gestational dia…
New data shows that some medications used for mental health during pregnancy may increase the risk of gestational diabetes.
Psychotropic medications and polypharmacy increase fall risk among older nursing home residents
Psychotropic Medications Linked to Higher Fall Risk in Nursing Homes
This meta-analysis of observational studies indicates that typical antipsychotics, atypical antipsychotics, sedative-hypnotics, and antidepr…
Certain medications used for mental health, including antipsychotics and antidepressants, are linked to a higher risk of falling for nursing…
PGx-guided antidepressants modestly increase short-term response and remission in MDD
Genetic testing may help patients find the right antidepressant
This meta-analysis examines pharmacogenomic-guided antidepressant treatment versus usual care in adults with major depressive disorder. Gene…
Using genetic tests to guide antidepressant choice may help more people with depression find relief during the first few months of treatment…
Antidepressants combined with psychotherapy do not significantly improve depression severity in major depressive disorder
Adding antidepressants to psychotherapy may not improve depression severity
This meta-analysis evaluated the efficacy of adding antidepressants to psychotherapy for patients with major depressive disorder. The analys…
New data suggests that adding antidepressant medication to talk therapy does not necessarily improve depression scores for people with major…
Antidepressant use is associated with a 1.34 increased risk of ventricular arrhythmia and sudden cardiac death
Antidepressant use linked to higher risk of sudden cardiac death
This meta-analysis of 9,619,278 patients found that antidepressant use, including SSRIs and TCAs, is associated with a significantly increas…
A massive study of over 9 million people shows a link between antidepressant use and a higher risk of serious heart rhythm problems.
GP review and hyperbolic tapering guidance increases antidepressant cessation rate to 14.9% at 12 months
New approach helps some patients stop taking antidepressants safely
This cluster randomized controlled trial of 483 adults on long-term antidepressants found that GP review with shared decision-making resourc…
A new method involving doctor reviews and guided tapering may help more people successfully stop antidepressant medication.
Serotonergic antidepressants associated with more than a 2-fold increase in odds of pseudarthrosis
Antidepressant use linked to higher risk of spinal fusion failure
This meta-analysis of 37,554 adult patients undergoing cervical or lumbar spinal fusion found that serotonergic antidepressant use was assoc…
A large review suggests that patients taking certain antidepressants may face a higher risk of failed spinal fusions during surgery.
Antidepressant-antipsychotic combination doubles likelihood of improvement in psychotic depression
Combination therapy doubles improvement odds in psychotic depression
This meta-analysis of randomized trials found that combination pharmacotherapy (antidepressant-antipsychotic) is associated with a significa…
For psychotic depression, pairing an antidepressant with an antipsychotic more than doubles the chance of improvement compared to other trea…
Serotonergic antidepressants and prolactin-elevating antipsychotics are associated with higher burdens of sexual dysfunction
Certain medications for depression and psychosis can cause sexual issues
This narrative review examines the impact of antidepressants and antipsychotics on sexual dysfunction in patients with depressive and psycho…
Some common treatments for mood and psychotic disorders may impact a patient's sex life, quality of life, and their ability to stay on medic…
Yoga with education yields clinically relevant improvements for depressive symptoms and pain in chronic low back pain
Yoga and Education Show Promise for Back Pain and Depression
This meta-analysis evaluates interventions for individuals with comorbid depressive symptoms and chronic nonspecific low back pain. Yoga wit…
A review of 834 patients suggests that yoga combined with education may improve both chronic back pain and depressive symptoms.
Drug-induced osteoporosis mechanisms and gut microbiota links remain largely unresolved for most medication classes
Many common medicines might change gut bacteria and affect bone strength in older adults
This narrative review examines the association between medications such as glucocorticoids and aromatase inhibitors and gut microbiota alter…
Some drugs like antidepressants and seizure medicines can alter gut bacteria. Scientists are still studying if these changes hurt bones or c…
Maintenance antidepressants show no effect on happy face recognition in adults with recurrent depression
Adults stopping antidepressants did not show worse mood face reading skills after one year of follow up time
This randomized controlled trial in 478 adults with recurrent depression found no evidence that discontinuing maintenance antidepressants al…
People with recurrent depression who stopped taking their medicine did not read happy faces differently than those who kept taking it. Their…
All antidepressants Articles
- Prenatal exposure to certain psychotropic medications is associated with increased risk of gestational diabetes
- Psychotropic medications and polypharmacy increase fall risk among older nursing home residents
- Antidepressants combined with psychotherapy do not significantly improve depression severity in major depressive disorder
- PGx-guided antidepressants modestly increase short-term response and remission in MDD
- Antidepressant use is associated with a 1.34 increased risk of ventricular arrhythmia and sudden cardiac death
- GP review and hyperbolic tapering guidance increases antidepressant cessation rate to 14.9% at 12 months
- Serotonergic antidepressants associated with more than a 2-fold increase in odds of pseudarthrosis
- Antidepressant-antipsychotic combination doubles likelihood of improvement in psychotic depression
- Serotonergic antidepressants and prolactin-elevating antipsychotics are associated with higher burdens of sexual dysfunction
- Yoga with education yields clinically relevant improvements for depressive symptoms and pain in chronic low back pain
- Drug-induced osteoporosis mechanisms and gut microbiota links remain largely unresolved for most medication classes
- Maintenance antidepressants show no effect on happy face recognition in adults with recurrent depression
- In a cohort of 561 individuals with chronic pain, sex and gender identity influenced repeated prescription refill odds
- PETRUSHKA decision-support tool reduced treatment discontinuation and improved symptoms in major depressive disorder
- Observational study examines antidepressant use patterns by sex and marital status in US adults