Serotonergic antidepressants associated with more than a 2-fold increase in odds of pseudarthrosis
Antidepressant use linked to higher risk of spinal fusion failure
This meta-analysis of 37,554 adult patients undergoing cervical or lumbar spinal fusion found that serotonergic antidepressant use was assoc…
A large review suggests that patients taking certain antidepressants may face a higher risk of failed spinal fusions during surgery.
Stand-alone ALIF shows higher reoperation risk for pseudarthrosis vs combined fixation
Adding screws to spinal fusion may reduce reoperation risk
This systematic review and meta-analysis of 917 patients found that stand-alone ALIF had a numerically higher but not statistically signific…
Spinal fusion with added screws lowered the need for repeat surgery by nearly 7 times, but fusion rates were similar.