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Home › Medications › chemotherapy

chemotherapy

52 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of chemotherapy

49 trials tracked of chemotherapy: 18 in phase 3 or 4 and 8 with published results. The most-cited published study has 652 citations.

49Trials tracked
18Phase 3 & 4
0Recruiting
8With published results
Phase distribution
Phase 4 1 Phase 3 17 Phase 2 21 Phase 1 2 Other / NA 8
  1. Phase 3 S0500 Treatment Decision Making Based on Blood Levels of Tumor Cells for Metastatic Breast Cancer Treated With Chemo Completed · 652 cited
  2. Phase 3 Quizartinib With Standard of Care Chemotherapy and as Continuation Therapy in Patients With Newly Diagnosed FLT3-ITD (+) Acute Myeloid Leukemia (AML) Completed · 406 cited
  3. Phase 3 ARIEL4: A Study of Rucaparib Versus Chemotherapy BRCA Mutant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients Completed · 145 cited
  4. Phase 3 Study of Rogaratinib (BAY1163877) vs Chemotherapy in Patients With FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma Completed · 101 cited
  5. Phase 3 Standard Chemotherapy vs. Chemotherapy Guided by Cancer Stem Cell Test in Recurrent Glioblastoma Completed · 43 cited
  6. Phase 3 AZD9291 (Osimertinib) Versus Platinum-Based Doublet-Chemotherapy in Locally Advanced or Metastatic Non-Small Cell Lung Cancer Completed · 28 cited
Show 43 more trials
  1. Phase 3 Neugranin in Breast Cancer Participants Receiving Doxorubicin/Docetaxel Completed · 26 cited
  2. Phase 3 Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery Completed · 13 cited
  3. Phase 4 Progression Free Survival (PFS) Using Erlotinib for Non-Small-Cell Lung Cancer (NSCLC) in Chinese Population Completed
  4. Phase 3 A Global Study of the Efficacy and Safety of Midostaurin + Chemotherapy in Newly Diagnosed Patients With FLT3 Mutation Negative (FLT3-MN) Acute Myeloid Leukemia (AML) Completed
  5. Phase 3 Stereotactic Radiology Versus Chemotherapy for Recurrent/Progressive Glioblastoma After Second-Line Chemotherapy Completed
  6. Phase 3 THOR Study: A Study of Continued Herceptin (Trastuzumab) in Combination With Second Line Chemotherapy in Patients With HER2 Positive Metastatic Breast Cancer. Completed
  7. Phase 3 A Study of Avastin (Bevacizumab) Plus Crossover Fluoropyrimidine-Based Chemotherapy in Patients With Metastatic Colorectal Cancer. Completed
  8. Phase 3 A Randomized Phase III Study of Vitamins B6 and B12 to Prevent Chemotherapy-Induced Neuropathy in Cancer Patients Completed
  9. Phase 3 A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Breast Cancer Progressing After First-Line Therapy With Avastin and Chemotherapy (TANIA) Completed
  10. Phase 3 GSK1120212 vs Chemotherapy in Advanced or Metastatic BRAF V600E/K Mutation-positive Melanoma Completed
  11. Phase 3 Adjuvant Chemotherapy in Treating Women Who Have Undergone Resection for Relapsed Breast Cancer; Chemotherapy as Adjuvant for LOcally Recurrent Breast Cancer Completed
  12. Phase 3 A Study of Erlotinib (Tarceva) Versus Gemcitabine/Cisplatin as First-line Treatment in Patients With Non-small Cell Lung Cancer With EGFR Mutations Completed
  13. Phase 2 Safety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer Setting Completed
  14. Phase 2 A Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204) Completed
  15. Phase 2 Pembrolizumab in Metastatic Castration Resistant Prostate Cancer (mCRPC) With or Without DNA Damage Repair Defects Completed
  16. Phase 2 Study Assessing Safety and Efficacy of Combination of BL-8040 and Pembrolizumab in Metastatic Pancreatic Cancer Patients Completed
  17. Phase 2 The CHARM Trial: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts Completed
  18. Phase 2 Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Completed
  19. Phase 2 Gemcitabine With Abraxane and Other Investigational Therapies in Neoadjuvant Treatment of Pancreatic Adenocarcinoma Completed
  20. Phase 2 Bevacizumab and Chemoembolization in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery Completed
  21. Phase 2 Evaluation Of The Efficacy Of The Combination Of Axitinib With Pemetrexed And Cisplatin In The Treatment Of Non-Squamous Non-Small Cell Lung Cancer Completed
  22. Phase 2 Cilengitide and Cetuximab in Combination With Platinum-based Chemotherapy as First-line Treatment for Subjects With Advanced Non Small Cell Lung Cancer (NSCLC) Completed
  23. Phase 2 Neoadjuvant Chemotherapy Versus Radiochemotherapy for Cancer of the Esophagus or Cardia Completed
  24. Phase 2 Chemoradiotherapy in Stage III Non-small Cell Lung Cancer (NSCLC) Completed
  25. Phase 2 A Study of Bevacizumab in Previously Untreated Extensive-Stage Small Cell Lung Cancer (SALUTE) Completed
  26. Phase 2 Study of Chemotherapy With Cisplatin/Carboplatin, and Docetaxel With or Without Erlotinib in Patients With Head and Neck Squamous Cell Carcinomas Amenable for Surgical Resection Completed
  27. Phase 2 Kanglaite Reduce the Toxicity of Radiotherapy of Head and Neck Cancer Phase II Study Completed
  28. Phase 2 Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or Leg Completed
  29. Phase 2 Study Of SU011248 Versus Chemotherapy For Patients With Previously Treated Triple Receptor Negative Breast Cancer Completed
  30. Phase 2 NOLAN: Naproxen or Loratadine and Neulasta Completed
  31. Phase 2 A Study Evaluating the Efficacy and the Safety of First-line Chemotherapy Combined With the Therapeutic Vaccine Named TG4010 and Nivolumab in Patients With Advanced Non-squamous Non-Small Cell Lung Cancer (NSCLC) Completed
  32. Phase 2 Involved Field Elective Volume De-Intensification Radiation Therapy for Head and Neck Cancer Completed
  33. Phase 2 CetuGEX™ in Comparison to Cetuximab for the Treatment of Patients With Head and Neck Cancer Completed
  34. Phase 1 A Phase 1 Dose-escalation Study to Evaluate the Safety and Pharmacokinetics (PK) of Palifermin in Subjects With Acute Leukemias Undergoing HSCT Completed
  35. Phase 1 A Study On An Immunostimulant Antibody In Combination With Chemotherapy For Advanced Cancer Of The Pancreas Completed
  36. N/A Stereotactic Radiotherapy in Locally Advanced Pancreatic Cancer With Different Biological Effective Doses Completed
  37. N/A Neural Progenitor Cell Sparing Radiation Therapy Plus Temozolomide Completed
  38. N/A Treatment for Relapsed/Refractory AML Based on a High Throughput Drug Sensitivity Assay Completed
  39. N/A Impact of Chemotherapy Followed by Aromatase Inhibitors on Bone Health of Women With ER-positive Early Breast Cancer Completed
  40. N/A Different Patterns of Target Delineation in SBRT for Locally Advanced Pancreatic Cancer Completed
  41. N/A Outpatient Induction Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome Completed
  42. N/A A Study of Rituximab in Combination With Chemotherapy in Relapsed/Refractory Follicular Lymphoma Completed
  43. N/A An Observational Study of First-Line Capecitabine Based Chemotherapy in Participants With Metastatic Colorectal Cancer Completed

Showing the 49 most-cited and recently-updated of 49 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
SCOPE platform predicts outcomes for metastatic colorectal and pancreatic cancers using organoid screening
Oncology Phase III
SCOPE platform predicts outcomes for metastatic colorectal and pancreatic cancers using organoid screening A Lab-Built Tumor Test May Predict If Cancer Drugs Will Work
This preclinical platform development study utilized a machine learning system integrating patient-derived organoids and clinical data to pr…
A platform called SCOPE uses tiny lab-grown copies of a patient's tumor to predict — before a large trial even starts — whether a cancer dru…
medRxiv Apr 18, 2026
Combining chemotherapy, immunotherapy, and high-dose radiation achieved remission in a patient with cervical esophageal adenocarcinoma
Oncology RCT
Combining chemotherapy, immunotherapy, and high-dose radiation achieved remission in a patient with cervical esophageal adenocarcinoma Rare throat cancer vanishes after bold three-pronged treatment
This case report describes a 39-year-old male with cervical esophageal adenocarcinoma treated with standard chemotherapy and immunotherapy c…
A 39-year-old man with rare throat cancer reached complete remission after doctors combined chemo, immunotherapy, and high-dose radiation.
Frontiers Apr 15, 2026
Intravenous vitamin C did not reduce gastrointestinal toxicities but attenuated platelet decline in nasopharyngeal carcinoma patients
Oncology RCT
Intravenous vitamin C did not reduce gastrointestinal toxicities but attenuated platelet decline in nasopharyngeal carcinoma patients Intravenous vitamin C may help protect platelets during cancer treatment in Thailand
A randomized, double-blind, placebo-controlled trial in Thailand assessed 2 g of intravenous vitamin C prior to chemotherapy in patients wit…
Intravenous vitamin C helped slow platelet loss in Thai cancer patients undergoing treatment, though it did not reduce common side effects l…
Apr 14, 2026
Network meta-analysis of adjuvant chemotherapy regimens for early-stage breast cancer identifies optimal dosing sequences and safety profiles
Oncology Meta-analysis
Network meta-analysis of adjuvant chemotherapy regimens for early-stage breast cancer identifies optimal dosing sequences and safety profiles New analysis suggests specific chemo schedules may improve outcomes for early breast cancer patients
This network meta-analysis evaluated Phase II and Phase III trials involving 17,187 women with early-stage breast cancer receiving adjuvant…
A new analysis of 17,187 women with early breast cancer suggests specific chemo schedules may improve outcomes and reduce side effects.
Apr 9, 2026