Clozapine Use Linked to Higher SARS-CoV-2 Infection Risk in Severe Mental Disorders
Clozapine users faced higher risk of severe COVID-19 in large study
A meta-analysis of 155,945 outpatients with severe mental disorders found that clozapine users had a higher rate of SARS-CoV-2 infection com…
A massive analysis of over 155,000 people found that those taking clozapine had higher rates of infection and worse outcomes from COVID-19.
Systematic review and meta-analysis finds 50% prevalence of antipsychotic polypharmacy in MENAT/EMRO countries
Half of Schizophrenia Patients Take Multiple Drugs at Once
This systematic review and meta-analysis of 17 studies (6,053 individuals) from MENAT/EMRO countries found a pooled prevalence of antipsycho…
New data reveals half of patients with schizophrenia in the Middle East take multiple antipsychotic drugs at once.
Observational study evaluates dynamic prediction model for clozapine initiation in Danish schizophrenia patients
Can we predict who needs clozapine soon? A new model says yes for many patients.
This observational research article evaluates a dynamic prediction model designed to forecast incident clozapine prescriptions within 365 da…
A new model predicts which schizophrenia patients need clozapine within a year, helping doctors start this life-saving treatment sooner for …
Clozapine, olanzapine, or haloperidol reduced assaults in 99 individuals with schizophrenia and assaultive behaviors.
Does the right antipsychotic drug reduce violence in people with schizophrenia and conduct disorder?
This RCT evaluated clozapine, olanzapine, or haloperidol in 99 individuals with schizophrenia and assaultive behaviors. Reductions in assaul…
Clozapine reduced violent urges in schizophrenia patients even when their mental symptoms did not improve, suggesting a direct calming effec…