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Home › Medications › corticosteroids

corticosteroids

51 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of corticosteroids

34 trials tracked of corticosteroids: 26 in phase 3 or 4 and 5 with published results. The most-cited published study has 245 citations.

34Trials tracked
26Phase 3 & 4
0Recruiting
5With published results
Phase distribution
Phase 4 11 Phase 3 15 Phase 2 7 Other / NA 1
  1. Phase 4 Advancing Renal TRANSplant eFficacy and Safety Outcomes With an eveRolimus-based regiMen (TRANSFORM) Completed · 245 cited
  2. Phase 3 An Efficacy and Safety Study of Tocilizumab (RoActemra/Actemra) in Participants With Giant Cell Arteritis (GCA) Completed · 133 cited
  3. Phase 4 Efficacy of Everolimus in Combination With Tacrolimus in Liver Transplant Recipients Completed · 30 cited
  4. Phase 3 12 Month Athena Study: Everolimus vs. Standard Regimen in de Novo Kidney Transplant Patients Completed · 13 cited
  5. Phase 3 Caplacizumab and Immunosuppressive Therapy Without Firstline Therapeutic Plasma Exchange in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura Completed · 2 cited
  6. Phase 4 A Study Investigating the Renal Tolerability, Efficacy, and Safety of a CNI-free Versus a Standard Regimen in de Novo Heart Transplant (HTx) Recipients Completed
Show 28 more trials
  1. Phase 4 SCHEDULE Follow Up Visit 5-7 yr Completed
  2. Phase 4 Kidney Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Kidney Transplant Recipients Completed
  3. Phase 4 A Study of CellCept (Mycophenolate Mofetil) Combined With Tacrolimus and Corticosteroids in Kidney Transplant Patients. Completed
  4. Phase 4 A Twelve-month, Multicenter, Open-label, Randomized Study of the Safety, Tolerability and Efficacy of Everolimus With Basiliximab, Corticosteroids and Two Different Exposure Levels of Tacrolimus in de Novo Renal Transplant Recipients Completed
  5. Phase 4 Evaluation of Early Conversion to Everolimus From Cyclosporine in de Novo Renal Transplant Recipients Completed
  6. Phase 4 SCHEDULE - Scandinavian Heart Transplant Everolimus de Novo Study With Early Calcineurin Inhibitor (CNI) Avoidance Completed
  7. Phase 4 Efficacy and Safety of Everolimus With Enteric-Coated Mycophenolate Sodium (EC-MPS) in a Cyclosporine Microemulsion-free Regimen Compared to Standard Therapy in de Novo Renal Transplant Patients Completed
  8. Phase 4 Efficacy and Safety of Everolimus+EC-MPS After Early CNI Elimination vs EC-MPS +Tacrolimus in Renal Transplant Recipients Completed
  9. Phase 3 A National Multi-center Randomized, Open Label Study to Evaluate Efficacy and Safety of Everolimus With EC-MPS Compared to Standard Treatment Combination Tacrolimus and EC-MPS in de Novo Liver Transplant Recipients Completed
  10. Phase 3 Tacrolimus/Everolimus Versus Tacrolimus/Enteric-Coated Mycophenolate Sodium Completed
  11. Phase 3 A Study of Omalizumab (Xolair) in Subjects With Moderate to Severe Persistent Asthma (EXTRA) Completed
  12. Phase 3 Enteric-coated Mycophenolate Sodium (EC-MPS) With Reduced-dose Tacrolimus Versus EC-MPS With Standard-dose Tacrolimus in Stable Kidney Transplant Recipients Completed
  13. Phase 3 Efficacy and Safety Study of Everolimus Plus Reduced Cyclosporine Versus Mycophenolic Acid Plus Cyclosporine in Kidney Transplant Recipients Completed
  14. Phase 3 Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients Completed
  15. Phase 3 Efficacy and Safety of Everolimus in Recipients of Heart Transplants to Prevent Acute and Chronic Rejection Completed
  16. Phase 3 A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA) Completed
  17. Phase 3 Progression of Renal Interstitial Fibrosis / Tubular Atrophy (IF/TA) According to Epithelial-mesenchymal Transition (EMT) and Immunosuppressive Regimen (Everolimus Based Versus CNI Based) in de Novo Renal Transplant Recipients Completed
  18. Phase 3 Extension Study to Evaluate the Long-term Efficacy and Safety of Everolimus in Liver Transplant Recipients Completed
  19. Phase 3 A Study of CellCept (Mycophenolate Mofetil) in Combination Therapy in Heart Transplant Patients. Completed
  20. Phase 3 Study Evaluating Sirolimus in Kidney Transplant Recipients Completed
  21. Phase 2 Pharmacodynamics, Efficacy and Safety of Basiliximab 40 or 80 mg in Combination With Ciclosporine Microemulsion or Everolimus, in Adult Low Risk de Novo Renal Transplant Recipients (IDEALE Study) Completed
  22. Phase 2 Study Comparing the Safety and Efficacy of Belatacept With That of Cyclosporine in Patients With a Transplanted Kidney Completed
  23. Phase 2 Combined Kidney and Bone Marrow Transplantation to Prevent Kidney Transplant Rejection Completed
  24. Phase 2 Regimen Optimization Study Completed
  25. Phase 2 Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver Transplant Completed
  26. Phase 2 A Study Comparing Obinutuzumab (RO5072759; GA101) 1000 Milligram (mg) Versus 2000 mg in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (GAGE) Completed
  27. Phase 2 A Study to Assess the Safety and Efficacy of Alefacept in Kidney Transplant Recipients Completed
  28. N/A A Randomized, Double-Blinded, Placebo-Controlled Trial of Corticosteroid Therapy Following Portoenterostomy Completed

Showing the 34 most-cited and recently-updated of 34 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Systematic review and meta-analysis of herpes zoster risk in rheumatoid arthritis patients
Rheumatology Meta-analysis
Systematic review and meta-analysis of herpes zoster risk in rheumatoid arthritis patients Rheumatoid Arthritis Patients Face Higher Shingles Risk Than General Public
This systematic review and meta-analysis synthesized data on herpes zoster risk in rheumatoid arthritis patients. The pooled proportion of h…
People with rheumatoid arthritis have a much higher chance of getting shingles, and doctors must watch for specific risk factors like high s…
Frontiers May 9, 2026
Systematic review and meta-analysis of repeat corticosteroids in PPROM shows increased maternal infection risk
Pulmonology & Critical Care Meta-analysis
Systematic review and meta-analysis of repeat corticosteroids in PPROM shows increased maternal infection risk Repeat steroid shots for PPROM may raise infection risk without helping babies
This systematic review and meta-analysis evaluated repeat courses of corticosteroids versus a single course in women with preterm premature …
A new review suggests giving two rounds of steroids to women with PPROM could hurt the mother without helping the baby
May 7, 2026
Montelukast vs Tiotropium Added to ICS in Children With Asthma
Allergy & Immunology RCT
Montelukast vs Tiotropium Added to ICS in Children With Asthma Asthma Treatment Comparison Shows Mixed Results for Kids
This randomized controlled trial in 152 children aged 6 to 14 years with partly controlled or uncontrolled asthma found no significant diffe…
A small trial found no clear difference between two asthma medicines for children, though one caused rare side effects.
May 1, 2026
Clinical features and treatment responses in 40 male patients with VEXAS syndrome
Neurology Cohort
Clinical features and treatment responses in 40 male patients with VEXAS syndrome HMA treatment shows promise for VEXAS syndrome patients
This retrospective multicenter study of 40 male patients with VEXAS syndrome evaluated clinical features and various treatment responses.
New data on VEXAS syndrome suggests that hypomethylating agents may help improve clinical and biological responses in men.
Frontiers Apr 30, 2026
Guideline narrative review discusses diabetes risks from immunosuppressive therapy in kidney transplant recipients
Nephrology Guideline
Guideline narrative review discusses diabetes risks from immunosuppressive therapy in kidney transplant recipients Guidelines address diabetes risks in kidney transplant patients
This publication is a narrative review guideline addressing Post-transplant diabetes mellitus and Type 2 Diabetes.
New guidance outlines considerations for kidney transplant patients dealing with diabetes and medication risks associated with therapy.
Frontiers Apr 29, 2026
Narrative review links myasthenia gravis and autoimmune encephalitis risk
Neurology Sys. Review
Narrative review links myasthenia gravis and autoimmune encephalitis risk MG and Brain Inflammation Linked in New Review
This narrative review examines the association between myasthenia gravis and autoimmune encephalitis.
This review reveals that myasthenia gravis is often linked to brain inflammation — and that may change how doctors treat tough cases.
Frontiers Apr 24, 2026
Invasive aspergillosis after COVID-19 linked to higher 14-day mortality than after influenza
Rheumatology Cohort
Invasive aspergillosis after COVID-19 linked to higher 14-day mortality than after influenza Why COVID-19 Makes Lung Fungus Deadlier
This retrospective cohort study of 45 IAPA and 82 CAPA patients found that 14-day mortality risk was 4.92 times higher for CAPA versus IAPA.
Imagine a patient fighting a severe lung infection.
Frontiers Apr 24, 2026
Meta-analysis links higher FT3 and TgAb to permanent hypothyroidism after subacute thyroiditis
Diabetes & Endocrinology Meta-analysis
Meta-analysis links higher FT3 and TgAb to permanent hypothyroidism after subacute thyroiditis After Thyroid Inflammation, Some Patients Face Lifelong Hormone Issues—New Clues Explain Why
This systematic review and meta-analysis of 1294 patients with subacute thyroiditis found that higher free triiodothyronine (FT3) levels and…
This research helps doctors predict which patients will need lifelong thyroid medication after inflammation, allowing for earlier monitoring…
Frontiers Apr 22, 2026
Systematic Review and Network Meta-Analysis Compares Enteral Nutrition and Medications in Pediatric Crohn's Disease
Pediatrics Meta-analysis
Systematic Review and Network Meta-Analysis Compares Enteral Nutrition and Medications in Pediatric Crohn's Disease Exclusive nutrition therapy beats steroids for healing Crohn's in kids
This systematic review and network meta-analysis evaluates enteral nutrition versus immunomodulators and corticosteroids in 1,182 pediatric …
Exclusive nutrition therapy was far better than steroids at healing Crohn's disease in children, with fewer side effects and no serious risk…
Frontiers Apr 22, 2026
Narrative review examines immunotherapy options for anti-GQ1b antibody syndromes including BBE and Miller Fisher syndrome
Neurology Sys. Review
Narrative review examines immunotherapy options for anti-GQ1b antibody syndromes including BBE and Miller Fisher syndrome A Rare Brainstem Condition Has a New Diagnostic Map
This narrative review evaluates the role of immunotherapy in patients with anti-GQ1b antibody syndromes, including Bickerstaff Brainstem Enc…
A new model groups rare brain disorders causing double vision and balance problems into one clear spectrum to help doctors diagnose confusin…
Frontiers Apr 21, 2026
Mechanistic review discusses host-directed therapy for children with Long COVID and secondary bacterial pneumonia
Primary Care & Family Medicine Sys. Review
Mechanistic review discusses host-directed therapy for children with Long COVID and secondary bacterial pneumonia Could monitoring specific blood markers help prevent long-term lung damage in kids with Long COVID?
This mechanistic review addresses Long COVID, Post-Acute Sequelae of SARS-CoV-2 infection, and secondary bacterial pneumonia in children.
Monitoring blood markers like ferritin and D-dimer could help doctors catch dangerous lung inflammation early in kids with Long COVID before…
Frontiers Apr 20, 2026
Systematic review of immunosuppression for SLE-associated intestinal pseudo-obstruction
Allergy & Immunology Meta-analysis
Systematic review of immunosuppression for SLE-associated intestinal pseudo-obstruction SLE Can Shut Down the Gut — But It Might Be Reversible
This review synthesized 43 cases of SLE-associated intestinal pseudo-obstruction.
Lupus can paralyze the gut without a blockage, but early treatment with immunosuppressives often reverses this dangerous complication.
Frontiers Apr 20, 2026