Systemic corticosteroids associated with greater hearing gain than intratympanic therapy in idiopathic SSNHL
Systemic steroids beat ear drops for sudden hearing loss
This single-center retrospective cohort study evaluated 284 adults with idiopathic sudden sensorineural hearing loss comparing initial syste…
Taking steroids by mouth or IV works better than putting them in the ear for sudden hearing loss.
VEXAS Syndrome Clinical Features and Treatment Outcomes in a Chinese Cohort of 16 Patients
Small study links UBA1 gene variants to blood and inflammatory issues in China
This retrospective cohort study of 16 Chinese patients describes main clinical features and treatment responses in VEXAS syndrome. Constitut…
A specific genetic change called a UBA1 variant was found in 81 percent of patients in China with blood disorders and inflammation affecting…
Guselkumab showed improved clinical remission in refractory ulcerative colitis versus placebo
Guselkumab shows promise for ulcerative colitis in this early phase 3 trial.
This phase 3 randomized trial evaluated guselkumab in adults with moderately to severely active ulcerative colitis who had inadequate respon…
Patients with ulcerative colitis who failed other treatments achieved remission in a new trial using subcutaneous guselkumab injections.
Case report details KFD patient developing SLE treated with immunosuppression
Your stomach hurts. You throw up. You think it is just food poisoning. But what if your immune system is fighting a hidden battle inside your lymph nodes? This story is about a rare condition that tricks doctors and changes a patient's life forever.
This case report describes a single patient with Kikuchi-Fujimoto disease who subsequently developed systemic lupus erythematosus. The autho…
Severe stomach pain and vomiting from a rare immune disorder can hide a hidden battle in your lymph nodes that tricks doctors into missing t…
A single case report confirms rare IgE-mediated cocoa allergy causing anaphylaxis in a child.
Your Child's Chocolate Reaction Might Not Be Milk or Nuts
This systematic review and case report describes a 2-year-old female with a history of allergic rhinitis and tree nut anaphylaxis who experi…
Most chocolate reactions aren't the cocoa itself, but a rare toddler case proves true cocoa allergies exist and require careful testing to f…
Strategies to screen and reduce adverse events in patients with asthma using systemic corticosteroids
Asthma Patients Are Still Getting Too Many Steroids — Here Is Why That Matters
This systematic review examined real-world practice strategies aimed at identifying and screening patients at risk of adverse events associa…
Asthma patients face serious, preventable harm from overused systemic steroids, yet safer biologics aren't reaching enough people who need t…
Therapeutic plasma exchange in pediatric autoimmune diffuse alveolar hemorrhage shows 5 of 6 survival
Kids' Lungs Bleeding: Early Blood Swap Saves Lives
A retrospective cohort study of 6 pediatric patients with autoimmune diffuse alveolar hemorrhage requiring intensive care found that therape…
Early blood swaps saved six critically ill children with autoimmune lung bleeding, avoiding death in all cases treated with this urgent ther…
Podocyte morphometrics correlate with albuminuria and eGFR decline in IgA nephropathy cohort
Tiny Footprints Predict Kidney Disease Progression
A single-center observational cohort of 37 patients with glomerulonephritis found that high-resolution podocyte morphometrics correlated wit…
Tiny changes in kidney cell shapes now predict disease progression better than standard tests, offering earlier warnings for patients with I…
Review finds strongest support for HBOT plus corticosteroids in sudden hearing loss recovery
What's the best treatment for sudden hearing loss? A review looks at blood flow therapies.
A review of hemodynamic-based therapies for sudden sensorineural hearing loss (SSNHL) and Ménière's disease found the strongest evidence sup…
Combining hyperbaric oxygen therapy with steroids boosts hearing recovery in sudden hearing loss, but timing and severity affect the results…