PLEX and corticosteroids show highest clinical response rates in chronic inflammatory demyelinating polyradiculoneuropathy
New FcRn Inhibitors Show Promise for Chronic Inflammatory Neuropathy
This systematic review and network meta-analysis of 2,184 patients evaluated various treatments for chronic inflammatory demyelinating polyr…
Newer treatments like efgartigimod alfa may offer significant clinical responses and improved grip strength for patients with chronic inflam…
Adjunctive corticosteroids do not significantly reduce coronary artery abnormalities in patients with Kawasaki disease
Adding corticosteroids to Kawasaki disease treatment shows mixed results
This meta-analysis of 4106 patients evaluated adjunctive corticosteroids for Kawasaki disease. The study found no significant difference in …
Adding corticosteroids to standard Kawasaki disease treatment may shorten hospital stays but does not change heart health outcomes.
Corticosteroids added to antiviral therapy do not improve outcomes in herpes simplex virus encephalitis
Adding corticosteroids to antiviral therapy for herpes encephalitis shows no benefit
This meta-analysis of 209 patients with herpes simplex virus encephalitis (HSVE) found no significant difference in mortality or neurologica…
Adding steroids to antiviral drugs does not improve survival or outcomes for patients with herpes simplex virus encephalitis.
Add-on therapies fail to beat placebo in cutaneous sarcoidosis, but quality of life may improve
Corticosteroids Show Limited Success for Skin Sarcoidosis Treatment
This meta-analysis of 156 adults with cutaneous sarcoidosis found that pharmacological add-on therapies did not significantly improve clinic…
New analysis suggests that adding extra medications to corticosteroid treatment for skin sarcoidosis may not improve clinical results for pa…
Ozone injections are more effective than corticosteroids for short and medium term pain in knee osteoarthritis
Ozone injections may reduce knee pain more than corticosteroids
This meta-analysis of 409 patients compared intra-articular ozone injections to corticosteroid injections for knee osteoarthritis. The analy…
Ozone injections could offer a more effective way to manage pain and improve movement for people living with knee osteoarthritis.
Allogeneic hematopoietic stem cell transplantation provides salvage for refractory chronic immune thrombocytopenia in a child
Stem Cell Transplant Shows Potential for Refractory Immune Thrombocytopenia
This case report with literature review describes a 6-year-old child with refractory chronic immune thrombocytopenia who achieved complete r…
A stem cell transplant provided a path to remission for a child with a severe form of immune thrombocytopenia.
Corticosteroid exposure was associated with catatonia in two adolescent girls with encephalitis
Corticosteroids Linked to Catatonia in Two Teen Girls
This case report describes two adolescent girls who developed catatonia following corticosteroid therapy for encephalitis. The report notes …
Two teen girls developed catatonia after corticosteroid treatment, but recovered with care. A rare but important side effect to know.
Ferroptosis and the GPX4 axis contribute to inflammation and barrier dysfunction in autoimmune uveitis
Air Pollution May Worsen Uveitis Through Cell Death
This mini review explores the role of ferroptosis in autoimmune uveitis, focusing on how PM2.5 exposure and TGFBR1 modulation affect T cell …
Air pollution may worsen autoimmune uveitis by triggering a type of cell death in immune cells, new research suggests.
Antenatal corticosteroids provide substantial neonatal benefits for threatened preterm birth despite uncertain long-term effects
Maternal Stress and Placental Hormones May Impact Child Development
This narrative review examines the impact of maternal psychological distress, placental glucocorticoid pathways, and antenatal corticosteroi…
Research explores how maternal stress and placental hormone pathways may influence the brain development and behavior of children born prema…
Systemic therapies may complicate radiation-induced lung injury by sustaining inflammation or delaying repair
Systemic Treatments May Affect Radiation Lung Injury Recovery
This narrative review examines the management of pulmonary events in patients receiving thoracic radiotherapy and combination anticancer the…
New clinical perspectives help doctors distinguish between radiation damage and complications caused by systemic cancer treatments in lung p…
High-dose corticosteroids combined with IVIG or plasma exchange are preferred for triple-M syndrome
Triple-M Syndrome Linked to Immune Checkpoint Inhibitor Therapy
This systematic review of case reports and series examines the management of triple-M syndrome following immune checkpoint inhibitor therapy…
Patients receiving immune checkpoint inhibitors may develop triple-M syndrome, a serious combination of muscle, heart, and nerve issues requ…
Low-dose corticosteroids reduce 90-day mortality in adults with severe community-acquired pneumonia
Low dose steroids may lower death rates in severe lung infections
This meta-analysis of 4,622 patients found that low-dose corticosteroids (≤400 mg hydrocortisone-equivalent daily) significantly reduced sho…
A review of clinical trials suggests that low-dose corticosteroids can reduce 90-day mortality for adults with severe lung infections like p…