Ivonescimab-containing chemoimmunotherapy can trigger rare ADAMTS13 inhibitor-positive immune thrombotic thrombocytopenic purpura
New Case Highlights Rare Kidney Risk in Lung Cancer Treatment
This case report and literature review describes a patient with stage IVB lung adenocarcinoma who developed iTTP after receiving an ivonesci…
A single case report identifies a rare blood and kidney condition that can occur during specific lung cancer treatments involving ivonescima…
Thermal RFA reduces pain more than steroid injections in facet joint syndrome, but effect may not be clinically meaningful
Thermal Radiofrequency Ablation Shows Better Pain Relief Than Injections
This meta-analysis of randomized controlled trials compared thermal radiofrequency ablation (RFA) with corticosteroid injections for facet j…
A review of clinical trials shows that thermal radiofrequency ablation may provide more pain relief than corticosteroid injections for certa…
Upadacitinib shows rapid improvement in refractory acrodermatitis continua of Hallopeau
Upadacitinib Shows Promise for Treatment of Chronic Skin Condition
This case report and literature review describes a 54-year-old man with a 13-year history of isolated acrodermatitis continua of Hallopeau (…
A new case report shows how a specific medication helped a man with a rare, long-term skin condition and nail inflammation.
Ensitrelvir plus standard of care does not improve clinical recovery in hospitalized COVID-19 patients
Trial shows ensitrelvir does not improve recovery for COVID-19
This Phase 3 randomized controlled trial of 589 adults hospitalized with COVID-19 found that ensitrelvir added to standard of care did not s…
A large trial found that adding ensitrelvir to standard care did not speed up clinical recovery for adults hospitalized with COVID-19.
Oral propranolol remains the primary systemic treatment for infantile hemangioma with no superior alternatives
Propranolol Remains the Standard Treatment for Infantile Hemangioma
This meta-analysis of 2639 patients found that no active intervention, including corticosteroids or other beta-blockers, demonstrated statis…
A review of over 2,600 cases shows that while several drugs treat infantile hemangioma, oral propranolol remains a primary standard.
Immunosuppression with corticosteroids and cyclophosphamide leads to clinical improvement in AAV patients with hepatic granulomas
Treatment shows success for liver issues in specific autoimmune diseases
This systematic scoping review examines the rare manifestation of hepatic granulomatosis in patients with ANCA-associated vasculitides (AAV)…
Patients with rare liver granulomas and certain autoimmune conditions saw improvement when treated with standard immunosuppressive therapies…
Multimodal lung-protective strategies reduce BPD risk in preterm infants
New insights into managing lung damage in preterm infants
This narrative review synthesizes evidence on bronchopulmonary dysplasia (BPD) in preterm infants, highlighting its multifactorial pathophys…
Doctors are identifying key risk factors and treatment paths for bronchopulmonary dysplasia to better protect the lungs of premature babies.
Adjunctive steroids reduce mortality in adult TB meningitis patients but not in children
Steroids may lower death rates for adults with TB meningitis
This meta-analysis of 2028 patients found that adjunctive steroid therapy significantly reduced mortality in adults with TB meningitis (RR =…
Adding steroids to treatment can reduce deaths in adults with TB meningitis, but the results are not as clear for children.
Susceptibility-guided combination therapy improves neurological status and reduces abscess size in a patient with nocardiosis
Case report: Brain infection in autoimmune hepatitis patient
This case report describes the management of disseminated nocardiosis in a 55-year-old man with autoimmune hepatitis. The patient showed gra…
A man with autoimmune hepatitis developed a rare brain infection after immunosuppression. Doctors treated it successfully with targeted anti…
Corticosteroids, IVIG, antibiotics, and mechanical ventilation are associated with higher odds of invasive pulmonary aspergillosis
Corticosteroids and IVIG Linked to Higher Risk of Lung Infection
This systematic review and meta-analysis of 10 articles evaluates the risk of invasive pulmonary aspergillosis (SAPA) in patients with sever…
New data shows that certain treatments like corticosteroids and IVIG are linked to a higher risk of lung infections in patients with SFTS.
Anti-VEGF plus corticosteroids improves BCVA and reduces edema recurrence in BRVO and CRVO
Combination therapy improves vision for patients with retinal vein occlusion
This meta-analysis of 2040 patients found that anti-VEGF plus corticosteroid combination therapy resulted in better BCVA (MD -0.09) and redu…
Adding corticosteroids to anti-VEGF injections can improve vision and reduce the need for frequent eye injections in certain retinal conditi…
Corticosteroid and cyclophosphamide exposure are associated with higher mortality in Middle Eastern and North African SLE
Specific Medications Linked to Survival Rates in Lupus Patients
This meta-analysis of 3,478 adult patients in the MENA region found an all-cause mortality rate of 9.9% (95% CI: 7.2%-14.0%). While corticos…
New data identifies how specific medications and health conditions impact long-term survival for patients with systemic lupus erythematosus.