Systematic review and meta-analysis on adjunctive corticosteroids for orbital cellulitis in children
Steroids Help Kids With Eye Infections
This systematic review and meta-analysis evaluates the effectiveness and safety of adjunctive systemic corticosteroids compared with antibio…
Steroids may safely speed recovery for kids with serious eye infections, reducing swelling and pain without hiding the infection.
Scoping review synthesizes immunosuppressive strategies and outcomes in solid organ transplantation
New Drug Strategies Aim to Stop Your Body From Rejecting a Transplant
This scoping review examines immunosuppressive strategies for solid organ transplant patients, including conventional, biologic, and emergin…
New drug strategies aim to stop your body from attacking a new organ, protecting transplants longer while reducing dangerous side effects fr…
POEM in Allgrove syndrome shows earlier symptom onset and favorable outcomes versus idiopathic achalasia
New Hope for Rare Childhood Disorder Affecting Eating
This cohort study from Peking Union Medical College Hospital, China, compared peroral endoscopic myotomy (POEM) outcomes in 7 patients with …
A minimally invasive procedure now helps children with rare Allgrove syndrome eat without pain, offering long-term relief for those who once…
Systemic corticosteroids associated with greater hearing gain than intratympanic therapy in idiopathic SSNHL
Systemic steroids beat ear drops for sudden hearing loss
This single-center retrospective cohort study evaluated 284 adults with idiopathic sudden sensorineural hearing loss comparing initial syste…
Taking steroids by mouth or IV works better than putting them in the ear for sudden hearing loss.
VEXAS Syndrome Clinical Features and Treatment Outcomes in a Chinese Cohort of 16 Patients
Small study links UBA1 gene variants to blood and inflammatory issues in China
This retrospective cohort study of 16 Chinese patients describes main clinical features and treatment responses in VEXAS syndrome.
A specific genetic change called a UBA1 variant was found in 81 percent of patients in China with blood disorders and inflammation affecting…
Guselkumab showed improved clinical remission in refractory ulcerative colitis versus placebo
Guselkumab shows promise for ulcerative colitis in this early phase 3 trial
This phase 3 randomized trial evaluated guselkumab in adults with moderately to severely active ulcerative colitis who had inadequate respon…
Patients with ulcerative colitis who failed other treatments achieved remission in a new trial using subcutaneous guselkumab injections.
Case report details KFD patient developing SLE treated with immunosuppression
Your stomach hurts. You throw up. You think it is just food poisoning. But what if your immune system is fighting a hidden battle inside your lymph nodes? This story is about a rare condition that tricks doctors and changes a patient's life forever
This case report describes a single patient with Kikuchi-Fujimoto disease who subsequently developed systemic lupus erythematosus.
Severe stomach pain and vomiting from a rare immune disorder can hide a hidden battle in your lymph nodes that tricks doctors into missing t…
A single case report confirms rare IgE-mediated cocoa allergy causing anaphylaxis in a child
Your Child's Chocolate Reaction Might Not Be Milk or Nuts
This systematic review and case report describes a 2-year-old female with a history of allergic rhinitis and tree nut anaphylaxis who experi…
Most chocolate reactions aren't the cocoa itself, but a rare toddler case proves true cocoa allergies exist and require careful testing to f…
Strategies to screen and reduce adverse events in patients with asthma using systemic corticosteroids
Asthma Patients Are Still Getting Too Many Steroids — Here Is Why That Matters
This systematic review examined real-world practice strategies aimed at identifying and screening patients at risk of adverse events associa…
Asthma patients face serious, preventable harm from overused systemic steroids, yet safer biologics aren't reaching enough people who need t…
Therapeutic plasma exchange in pediatric autoimmune diffuse alveolar hemorrhage shows 5 of 6 survival
Kids' Lungs Bleeding: Early Blood Swap Saves Lives
A retrospective cohort study of 6 pediatric patients with autoimmune diffuse alveolar hemorrhage requiring intensive care found that therape…
Early blood swaps saved six critically ill children with autoimmune lung bleeding, avoiding death in all cases treated with this urgent ther…
Podocyte morphometrics correlate with albuminuria and eGFR decline in IgA nephropathy cohort
Tiny Footprints Predict Kidney Disease Progression
A single-center observational cohort of 37 patients with glomerulonephritis found that high-resolution podocyte morphometrics correlated wit…
Tiny changes in kidney cell shapes now predict disease progression better than standard tests, offering earlier warnings for patients with I…
Meta-analysis finds inhaled corticosteroids associated with reduced cardiovascular mortality in COPD patients
A Common COPD Medicine May Also Protect Your Heart
A systematic review and meta-analysis of 74,004 COPD patients found inhaled corticosteroid-containing formulations were associated with redu…
For people with COPD, a medication they already use to breathe easier might also offer a hidden layer of protection for their heart.