Corticosteroid and cyclophosphamide exposure are associated with higher mortality in Middle Eastern and North African SLE
Specific Medications Linked to Survival Rates in Lupus Patients
This meta-analysis of 3,478 adult patients in the MENA region found an all-cause mortality rate of 9.9% (95% CI: 7.2%-14.0%). While corticos…
New data identifies how specific medications and health conditions impact long-term survival for patients with systemic lupus erythematosus.
Low-dose ATG plus PTCy shows no significant difference in acute GVHD compared to standard regimens
Trial Shows New Treatment Strategy for Leukemia Stem Cell Transplant
This randomized trial of 407 patients with AML or MDS undergoing haploidentical transplant found that low-dose ATG plus PTCy did not signifi…
A new combination of medications may help patients recover blood cells faster after a stem cell transplant for leukemia or blood disorders.
Pola-R-CHP reduces progression risk 35% in double-expressor DLBCL, but OS unchanged
New Treatment Options Show Promise for Specific Lymphoma Patients
This network meta-analysis of 1,016 treatment-naïve patients with MYC/BCL2 double-expressor DLBCL found that Pola-R-CHP significantly reduce…
A new drug combination may reduce the risk of disease progression in patients with a specific type of lymphoma.
Tafasitamab plus lenalidomide and R-CHOP improves progression-free survival in high-risk DLBCL
Trial shows new treatment improves progression-free survival for lymphoma
This Phase 3 randomized, double-blind, placebo-controlled trial evaluated tafasitamab plus lenalidomide and R-CHOP in patients with high-ris…
A new drug combination showed improved progression-free survival for patients with high-risk large B-cell lymphoma in a Phase 3 clinical tri…
Venetoclax-based combinations show superior progression-free survival compared to chemoimmunotherapy in CLL without TP53 aberrations
Trial shows venetoclax combinations improve progression-free survival in CLL
This Phase 3 randomized controlled trial of 926 patients with CLL without TP53 aberrations found that venetoclax-based regimens (RV, GV, and…
New clinical trial results show that specific venetoclax combinations can keep chronic lymphocytic leukemia stable for longer than standard …
Reduced-dose craniospinal radiation and smaller volume boost for medulloblastoma patients
Trial Shows Reduced Radiation May Help Children With Medulloblastoma
This randomized phase 3 trial evaluated reduced-dose craniospinal radiation (18.00 Gy) and a smaller volume boost in children aged 3 to 7 wi…
A large clinical trial looked at whether reducing radiation doses for children with medulloblastoma can maintain safety and effectiveness.
Pleuropulmonary blastoma diagnosed after initial rhabdomyosarcoma interpretation in a 2-year-old boy
Case report shows rare lung cancer in toddler with DICER1
This case report describes a 2-year-old boy with a thoracic mass initially interpreted as embryonal rhabdomyosarcoma, later diagnosed as ple…
A toddler’s lung tumor was reclassified as a rare cancer linked to DICER1 syndrome, changing his treatment and highlighting a key diagnosis …
Phase II pilot study of hu14.18K322A plus chemotherapy in 153 children with high-risk neuroblastoma
New Antibody Boosts Survival in High-Risk Neuroblastoma
This Phase II pilot study enrolled 153 previously untreated children with high-risk neuroblastoma. The study assessed hu14.18K322A combined …
This study shows that combining a new antibody with standard chemotherapy may improve survival rates for children with high-risk neuroblasto…
Interval-compressed VDC/IE protocol feasibility and outcomes in 27 Ewing's sarcoma patients at a North African center
Compressed chemotherapy showed mixed results for Ewing's sarcoma patients in a small study.
This retrospective, single-institutional cohort study evaluated an interval-compressed VDC/IE protocol in 27 patients with Ewing's sarcoma t…
A small study found that a compressed chemotherapy regimen for Ewing's sarcoma had high toxicity and low survival rates.
Attenuated R-THP-COP regimen achieved complete response in an 85-year-old with diffuse large B-cell lymphoma
Attenuated R-THP-COP regimen shows promise for elderly diffuse large B-cell lymphoma
This case report describes an 85-year-old female patient with diffuse large B-cell lymphoma treated with an attenuated R-THP-COP regimen. Th…
An 85-year-old woman achieved complete radiological response and remained symptom-free for three years on an attenuated chemotherapy regimen…
TAC chemotherapy improves relapse-free survival in certain early breast cancer subtypes
Doctors found that certain tumor markers might help choose the best cancer treatment plan for some patients
A randomized trial compared TAC to ddAC in early breast cancer. The authors observed improved relapse-free survival in specific tumor subtyp…
This study looked at how two different drug schedules worked for people with early breast cancer. Results suggest that specific tumor featur…
Case report details treatment of ANCA-associated vasculitis with Evans syndrome and cerebral infarction in a 72-year-old woman
Treatment stabilized some symptoms but not others in a single patient case
This case report describes a 72-year-old female with ANCA-associated vasculitis, Evans syndrome, and cerebral infarction treated with cortic…
A 72-year-old woman with complex blood vessel disease saw some health markers improve while others remained poor after specific treatments.