Nalbuphine and midazolam show non-inferiority to pethidine and midazolam for oocyte retrieval pain
Nalbuphine Matches Old Painkiller For Egg Retrieval
In this double-blinded, non-inferiority randomized controlled trial of 94 participants, 10 mg intravenous nalbuphine with 5 mg midazolam was…
A new painkiller matches the old standard for egg retrieval without causing more side effects.
Increasing midazolam sedation levels associated with decreased energy expenditure in mechanically ventilated patients
Deep sedation reduces energy use in critically ill patients
In this prospective self-controlled study of 74 critically ill patients requiring mechanical ventilation, increasing levels of midazolam sed…
Deep sedation levels can lower how much energy the body burns in patients using mechanical ventilation.
Network meta-analysis of ketamine regimens for pediatric ED procedural sedation safety and efficacy
Ketamine combos ease pain in kids with less nausea
This network meta-analysis evaluated ketamine-based regimens versus IV ketamine for pediatric procedural sedation in the emergency departmen…
A new analysis reveals a ketamine-propofol mix calms injured children faster and with fewer side effects than ketamine alone.
Intranasal Dexmedetomidine Plus Midazolam Improves Sedation Success Versus Chloral Hydrate in Children
Dexmedetomidine Plus Midazolam Works Better for Kids
This randomized controlled trial enrolled 180 children aged 1–6 years undergoing outpatient procedural sedation. The dexmedetomidine plus mi…
A common sedation combo for children fails more often and causes more side effects than a better alternative most clinics already use.
Network meta-analysis of sedation strategies in therapeutic gastrointestinal endoscopy shows ketamine-propofol reduces hypoxia and bradycardia versus propofol-opioid.
Better Sedation Choices Could Reduce Side Effects During Stomach Tests
This network meta-analysis evaluated pharmacological sedation strategies in 7,071 patients undergoing therapeutic gastrointestinal endoscopy…
Mixing ketamine with propofol lowers breathing and blood pressure risks for patients undergoing long stomach procedures compared to standard…
Meta-analysis shows dexmedetomidine lowers mean arterial pressure compared to midazolam-fentanyl in surgical patients.
A Calmer Sedative May Make Surgery Safer for Patients
This systematic review and meta-analysis evaluated 259 surgical patients receiving either dexmedetomidine or midazolam-fentanyl during intra…
A newer sedative keeps patients calmer with steadier vitals and fewer breathing problems than the older standard combination during surgery.
Outpatient IV sedation for dental care in special needs patients shows 3.3% minor complication rate
Study describes use of IV sedation for dental care in patients with special needs
A retrospective cohort study of 212 special health care needs patients (mean age 11.1 years) undergoing outpatient IV sedation for dental pr…
Over 2,200 dental procedures were safely performed on children with autism and Down syndrome using IV sedation at a Venezuelan clinic, with …