Increasing midazolam sedation levels associated with decreased energy expenditure in mechanically ventilated patients
Deep sedation reduces energy use in critically ill patients
In this prospective self-controlled study of 74 critically ill patients requiring mechanical ventilation, increasing levels of midazolam sed…
Deep sedation levels can lower how much energy the body burns in patients using mechanical ventilation.
Conservative fluid management shows no difference in tissue perfusion or kidney injury in critically ill adults.
Less Fluid in ICU: New Data Shows It Is Safe
This secondary analysis of an RCT in critically ill patients found that conservative fluid management with active deresuscitation did not di…
Doctors can safely reduce fluids in sick patients without hurting their organs.
Individualized commercial formulation reduces diarrhea in adult ICU patients receiving tube-fed enteral nutrition.
Custom-Made Nutrition Cuts Diarrhea Risk in Half for ICU Patients
This retrospective cohort study of 605 adult ICU patients at Henan Provincial People's Hospital compared individualized commercial formulati…
For patients in the ICU who can’t eat normally, switching from a standard "one-size-fits-all" nutrition formula to a custom-made one could d…
Protocol outlines individualized anticoagulation monitoring in critically ill adults using unfractionated or low-molecular-weight heparin.
ICU Blood Clot Prevention Has a Monitoring Problem — This Study Aims to Fix It
This study protocol describes a prospective observational cohort design evaluating individualized anticoagulation monitoring in critically i…
A new prospective study is testing whether a real-time clotting test called viscoelastic testing can give ICU doctors a more complete pictur…
Testosterone gel fails to normalize serum levels in critically ill ICU patients in pilot RCT
Can testosterone gel help critically ill men? A small study finds no clear benefit.
A pilot RCT of 30 critically ill ICU patients on vasopressors and mechanical ventilation found 14-day testosterone gel administration did no…
Testosterone gel did not improve hormone levels or safety in critically ill men needing breathing machines and blood pressure support.