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Home › Medications › mirtazapine

mirtazapine

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of mirtazapine

12 trials tracked of mirtazapine: 3 in phase 3 or 4 and 1 with published results. The most-cited published study has 31 citations.

12Trials tracked
3Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 2 Phase 3 1 Phase 2 7 Other / NA 2
  1. Phase 3 Mirtazapine Treatment of Anxiety in Children and Adolescents With Pervasive Developmental Disorders Completed · 31 cited
  2. Phase 4 A Placebo-Controlled Study of Mirtazapine for PTSD Completed
  3. Phase 4 Combined Mirtazapine and SSRI Treatment of PTSD: A Placebo-Controlled Trial Completed
  4. Phase 2 Role of Mirtazapine in Ameliorating Sleep Disordered Breathing Completed
  5. Phase 2 A Study of Quetiapine and Mirtazapine for the Treatment of Alcohol Dependency Completed
  6. Phase 2 Efficacy of Mirtazapine in Depressed Cocaine Dependent Subjects Completed
Show 6 more trials
  1. Phase 2 Mirtazapine to Reduce Methamphetamine Use Among MSM With High-risk HIV Behaviors Completed
  2. Phase 2 Mirtazapine for Treating Cocaine Dependent Individuals Who Also Suffer From Depression Completed
  3. Phase 2 Treatment of Young Adults With Comorbid AUD/MDD: A Pilot Medication Trial Completed
  4. Phase 2 Double-blind Pilot Trial of Mirtazapine for the Treatment of Co-occurring AD/MDD. Completed
  5. N/A A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Completed
  6. N/A Non-interventional, Retrospective Cohort Study to Explore Antidepressant Treatment in Korea Completed

Showing the 12 most-cited and recently-updated of 12 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
DORAs show strongest evidence for insomnia while sedating antidepressants vary in antidepressant activity and side effects
Psychiatry Sys. Review
DORAs show strongest evidence for insomnia while sedating antidepressants vary in antidepressant activity and side effects Sedating Antidepressants and DORAs Show Different Benefits for Depression and Insomnia
This narrative review examines sedating antidepressants and dual orexin receptor antagonists (DORAs) for patients with major depressive diso…
New research highlights how different sedating antidepressants and DORAs offer varying levels of support for patients with depression and in…
Frontiers Sep 9, 2026
Mirtazapine reduces methamphetamine use in phase 3 trial
Drug Pipeline RCT
Mirtazapine reduces methamphetamine use in phase 3 trial Mirtazapine cuts meth use days more than placebo in adults with severe addiction
In a phase 3 RCT, mirtazapine 30 mg daily for 12 weeks led to a greater reduction in methamphetamine use days compared to placebo, with a me…
Adults with severe methamphetamine use disorder took less meth when on mirtazapine compared to placebo, with fewer days of use over 12 weeks…
Jun 7, 2026
Mirtazapine and olanzapine reduce anxiety and depression scores in oral cavity cancer patients
Oncology RCT
Mirtazapine and olanzapine reduce anxiety and depression scores in oral cavity cancer patients Two Common Pills Ease Cancer Anxiety and Depression
This randomized controlled trial included 144 patients with oral cavity cancer.
Two well-known antidepressants significantly eased anxiety and depression in oral cancer patients, with mirtazapine showing a slight edge.
Apr 29, 2026