Immediate antituberculosis therapy did not reduce mortality in HIV-related sepsis overall
Immediate TB treatment helps only those with confirmed infection in HIV sepsis
This trial investigated whether starting antituberculosis treatment immediately or using high doses improved survival in adults with HIV-rel…
In HIV sepsis, starting TB drugs immediately did not lower death rates overall, but helped only patients later confirmed to have TB.
Case report on Brucella periprosthetic joint infection after knee replacement
Two rare knee infections treated with specific antibiotics and surgery
This is a case report of two patients with Brucella-induced periprosthetic joint infection after total knee arthroplasty. The authors descri…
Two patients with rare Brucella knee infections saw normal markers and restored motion after targeted antibiotic therapy and surgery.
High-dose rifampicin pharmacokinetics differ across sites in tuberculosis infection randomized trial
High-dose rifampicin shows different drug levels in adults across three countries
This randomized controlled trial evaluated adults and adolescents aged ≥ 10 years with tuberculosis infection.
Drug levels of high-dose rifampicin varied by country, with lower bioavailability seen in Canada and Vietnam compared to Indonesia in this t…
Molecular epidemiology study of rifampicin-resistant TB in Vietnam shows high resistance to other drugs
Vietnam’s TB Crisis Hides a Dangerous Pattern
This molecular epidemiology study analyzed 252 rifampicin-resistant TB isolates from Vietnam using whole genome sequencing.
A hidden pattern in Vietnam’s tuberculosis cases reveals most drug-resistant strains also resist other key medicines, changing how doctors m…
Review Analytical Performance of Multiplex PCR Assays for Tuberculosis and Drug Resistance
New test spots TB and drug resistance in one quick scan
This review evaluates the comprehensive analytical performance of multiplex open real-time PCR assays for tuberculosis and drug resistance i…
A new lab test finds TB and drug resistance in one quick scan, but it misses some rare germs that need more study.
Systematic review of Mycobacterium riyadhense infection in 69 cases shows common presentations and drug susceptibility patterns
A rare infection hits lungs and bones: what doctors need to know about treating Mycobacterium riyadhense
A systematic review and meta-analysis of 69 immunocompetent and immunocompromised patients with Mycobacterium riyadhense infection found pne…
A rare lung and bone infection called Mycobacterium riyadhense often resists standard drugs, leaving doctors without agreed-upon treatment p…
Retrospective cohort study examines MRSA prevalence and resistance patterns in nosocomial bloodstream infections among 96 patients in central China
Are hospital infections getting harder to treat, or is the data stable?
This retrospective cohort study analyzed 96 Staphylococcus aureus isolates from patients with nosocomial bloodstream infections at a tertiar…
Hospital bloodstream infections from tough MRSA bacteria stayed stable in frequency, but one patient's germ was resistant to the last-resort…
Potential drug interactions did not affect rifampin TB prevention completion or adverse events
Do drug interactions make tuberculosis prevention harder to finish?
A secondary analysis of 1368 participants in a rifampin TPT trial found no difference in treatment completion or adverse events between thos…
Tuberculosis prevention treatment works safely with other drugs, but patients taking them face more unscheduled doctor visits during the cou…