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Home › Medications › rocuronium

rocuronium

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of rocuronium

42 trials tracked of rocuronium: 32 in phase 3 or 4 and 11 with published results. The most-cited published study has 380 citations.

42Trials tracked
32Phase 3 & 4
0Recruiting
11With published results
Phase distribution
Phase 4 22 Phase 3 10 Phase 2 2 Other / NA 8
  1. Phase 3 Comparison of Sugammadex (MK-8616/Org 25969) With Neostigmine Administered at 1-2 Post-tetanic Counts (PTCs) After Administration of Rocuronium or Vecuronium (19.4.302/P05945/MK-8616-025) Completed · 380 cited
  2. Phase 4 Neuromuscular Blockade During Transurethral Resection of Bladder Cancer Completed · 261 cited
  3. Phase 3 Comparison of Recovery From Rocuronium 1.2 mg/kg Followed by Sugammadex (Org 25969) 16 mg/kg at 3 Minutes With Recovery From Succinylcholine 1.0 mg/kg (19.4.303)(P05946)(MK-8616-026) Completed · 242 cited
  4. Phase 3 Dose-Finding Pediatric and Adult Trial With Sugammadex (Org 25969, MK-8616, SCH 900616) (19.4.306) (MK-8616-034) (P05961) Completed · 205 cited
  5. Phase 3 Safety and Efficacy of Sugammadex (Org 25969, MK-8616) in Participants With or Having a Past History of Pulmonary Disease (19.4.308) (P05932) (MK-8616-017) Completed · 56 cited
  6. Phase 3 Sugammadex After Continuous Infusion of Rocuronium During Sevoflurane and Propofol Anesthesia (P05949; MK-8616-028) Completed · 55 cited
Show 36 more trials
  1. Phase 4 Cognitive Functions After TIVA With Dexmedetomidine Completed · 26 cited
  2. Phase 4 Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145) Completed · 15 cited
  3. Phase 3 Use of Sugammadex at the End of Case in Routine Anesthesia (MK-8616-023) Completed · 2 cited
  4. Phase 4 Role of Sugammadex as Reversal Agent in Patients Extubated Immediately After Isolated Coronary Artery Bypass Grafting Surgery Completed
  5. Phase 4 Muscle Relaxation for Pediatric Adenotonsillectomy Completed
  6. Phase 4 Effects of Deep Neuromuscular Blockade on Intraoperative Respiratory Mechanics Completed
  7. Phase 4 Effect of Deep Neuromuscular Block on Surgical Conditions in Morbidly Obese Patients Completed
  8. Phase 4 Surgical Conditions During Laparoscopic Bariatric Surgery Completed
  9. Phase 4 Comparison of Surgical Conditions in Cesarean Section Under General Anesthesia With Deep Neuromuscular Blockade Versus Succinylcholine Completed
  10. Phase 4 Effect of Deep Neuromuscular Block (NMB), Inhalation or TIVA on Pneumoperitoneum. Completed
  11. Phase 4 Investigation of Sugammadex in Outpatient Urological Procedures Completed
  12. Phase 4 Can Adequacy of Anesthesia Depth and Quality of Recovery be Influenced by the Level of Neuromuscular Blockade? Completed
  13. Phase 4 Deep vs Moderate Neuromuscular Blockade With Rocuronium in Patients Undergoing Endolaryngeal Procedures Completed
  14. Phase 4 Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery Completed
  15. Phase 4 Opioid-Free Shoulder Arthroplasty Completed
  16. Phase 4 Recovery After Laparoscopic Hysterectomy With Deep Neuromuscular Blockade and Low Intra-abdominal Pressure Completed
  17. Phase 4 Optimizing Surgical Conditions During Gynecologic Laparoscopic Surgery With Deep Neuromuscular Blockade Completed
  18. Phase 4 Premedication for Non-Emergency Endotracheal Intubation In the NICU Completed
  19. Phase 4 Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block Completed
  20. Phase 4 The Muscle Relaxation-study Completed
  21. Phase 4 A Study Comparing the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures in Participants Undergoing Laparoscopic Cholecystectomy (P07982) Completed
  22. Phase 4 Succinylcholine Versus Rocuronium for Emergency Intubation in Intensive Care Completed
  23. Phase 3 Dialysis of Sugammadex in Participants With Severe Renal Impairment (Study 19.4.333) (P05773) Completed
  24. Phase 3 Comparison of Sugammadex Administered at 1-2 Post Tetanic Counts (PTCs) or Better With Neostigmine Administered as Per Standard of Care to Reverse Rocuronium-Induced Neuromuscular Blockade in Adults Undergoing Elective Open Abdominal Procedure (19.4.334) (P05774) Completed
  25. Phase 3 Rocuronium Plus Sugammadex Versus Succinylcholine Alone in Participants Undergoing Short Surgical Procedures (19.4.319)(P05700 AM2)(COMPLETED) Completed
  26. Phase 3 Comparison of Sugammadex With Neostigmine During Laparoscopic Cholecystectomy or Appendectomy (P05699) Completed
  27. Phase 2 Neuromuscular Blockade for Post-Cardiac Arrest Care Completed
  28. Phase 2 A Bridging Trial Comparing Sugammadex (Org 25969) at Reappearance of T2 in Japanese and Caucasian Participants. Part B: Caucasian Participants (P05971) Completed
  29. N/A Neuromuscular Blocking Agents in the Elderly Completed
  30. N/A Optimal Inspiratory Pressure for Facemask Pressure-controlled Ventilation in Children Completed
  31. N/A Optimal Dose of Succinylcholine and Rocuronium for Electroconvulsive Therapy (ECT) Completed
  32. N/A Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies Completed
  33. N/A Use of Neuromuscular Blocking Agents and Neuromuscular Monitoring in 7 Danish Teaching Hospitals Completed
  34. N/A Desflurane Versus Propofol in the Sitting Position Completed
  35. N/A Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade. Completed
  36. N/A The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy Completed

Showing the 42 most-cited and recently-updated of 42 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Sugammadex selectively reverses rocuronium blockade within 3 minutes, review reports
Drug Pipeline Sys. Review
Sugammadex selectively reverses rocuronium blockade within 3 minutes, review reports Sugammadex quickly reverses muscle paralysis caused by rocuronium
This narrative review examines sugammadex for reversal of neuromuscular blockade, covering mechanism of action, pharmacokinetics, dosing, ad…
A new way to quickly reverse muscle paralysis during surgery can work in under three minutes, helping patients wake up faster and safer.
Frontiers Sep 17, 2026
General anesthesia with reduced rocuronium and sugammadex reversal safely enabled cesarean section in a patient with inclusion body myositis
Anesthesiology & Pain Medicine Sys. Review
General anesthesia with reduced rocuronium and sugammadex reversal safely enabled cesarean section in a patient with inclusion body myositis A single case shows safe anesthesia for a pregnant patient with inclusion body myositis
This case report describes the perioperative anesthetic management of a 43-year-old pregnant patient with inclusion body myositis undergoing…
A 43-year-old pregnant patient with inclusion body myositis had a cesarean section without complications. Her baby scored 10 out of 10 on Ap…
Frontiers Jun 2, 2026