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Home › Medications › rocuronium

rocuronium

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials of rocuronium

42 trials tracked of rocuronium: 32 in phase 3 or 4 and 11 with published results. The most-cited published study has 374 citations.

42Trials tracked
32Phase 3 & 4
0Recruiting
11With published results
Phase distribution
Phase 4 22 Phase 3 10 Phase 2 2 Other / NA 8
  1. Phase 3 Comparison of Sugammadex (MK-8616/Org 25969) With Neostigmine Administered at 1-2 Post-tetanic Counts (PTCs) After Administration of Rocuronium or Vecuronium (19.4.302/P05945/MK-8616-025) Completed · 374 cited
  2. Phase 4 Neuromuscular Blockade During Transurethral Resection of Bladder Cancer Completed · 258 cited
  3. Phase 3 Comparison of Recovery From Rocuronium 1.2 mg/kg Followed by Sugammadex (Org 25969) 16 mg/kg at 3 Minutes With Recovery From Succinylcholine 1.0 mg/kg (19.4.303)(P05946)(MK-8616-026) Completed · 242 cited
  4. Phase 3 Dose-Finding Pediatric and Adult Trial With Sugammadex (Org 25969, MK-8616, SCH 900616) (19.4.306) (MK-8616-034) (P05961) Completed · 204 cited
  5. Phase 3 Safety and Efficacy of Sugammadex (Org 25969, MK-8616) in Participants With or Having a Past History of Pulmonary Disease (19.4.308) (P05932) (MK-8616-017) Completed · 55 cited
  6. Phase 3 Sugammadex After Continuous Infusion of Rocuronium During Sevoflurane and Propofol Anesthesia (P05949; MK-8616-028) Completed · 54 cited
Show 36 more trials
  1. Phase 4 Cognitive Functions After TIVA With Dexmedetomidine Completed · 26 cited
  2. Phase 4 Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145) Completed · 14 cited
  3. Phase 3 Use of Sugammadex at the End of Case in Routine Anesthesia (MK-8616-023) Completed · 2 cited
  4. Phase 4 Role of Sugammadex as Reversal Agent in Patients Extubated Immediately After Isolated Coronary Artery Bypass Grafting Surgery Completed
  5. Phase 4 Muscle Relaxation for Pediatric Adenotonsillectomy Completed
  6. Phase 4 Effects of Deep Neuromuscular Blockade on Intraoperative Respiratory Mechanics Completed
  7. Phase 4 Effect of Deep Neuromuscular Block on Surgical Conditions in Morbidly Obese Patients Completed
  8. Phase 4 Surgical Conditions During Laparoscopic Bariatric Surgery Completed
  9. Phase 4 Comparison of Surgical Conditions in Cesarean Section Under General Anesthesia With Deep Neuromuscular Blockade Versus Succinylcholine Completed
  10. Phase 4 Effect of Deep Neuromuscular Block (NMB), Inhalation or TIVA on Pneumoperitoneum. Completed
  11. Phase 4 Investigation of Sugammadex in Outpatient Urological Procedures Completed
  12. Phase 4 Can Adequacy of Anesthesia Depth and Quality of Recovery be Influenced by the Level of Neuromuscular Blockade? Completed
  13. Phase 4 Deep vs Moderate Neuromuscular Blockade With Rocuronium in Patients Undergoing Endolaryngeal Procedures Completed
  14. Phase 4 Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery Completed
  15. Phase 4 Opioid-Free Shoulder Arthroplasty Completed
  16. Phase 4 Recovery After Laparoscopic Hysterectomy With Deep Neuromuscular Blockade and Low Intra-abdominal Pressure Completed
  17. Phase 4 Optimizing Surgical Conditions During Gynecologic Laparoscopic Surgery With Deep Neuromuscular Blockade Completed
  18. Phase 4 Premedication for Non-Emergency Endotracheal Intubation In the NICU Completed
  19. Phase 4 Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block Completed
  20. Phase 4 The Muscle Relaxation-study Completed
  21. Phase 4 A Study Comparing the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures in Participants Undergoing Laparoscopic Cholecystectomy (P07982) Completed
  22. Phase 4 Succinylcholine Versus Rocuronium for Emergency Intubation in Intensive Care Completed
  23. Phase 3 Dialysis of Sugammadex in Participants With Severe Renal Impairment (Study 19.4.333) (P05773) Completed
  24. Phase 3 Comparison of Sugammadex Administered at 1-2 Post Tetanic Counts (PTCs) or Better With Neostigmine Administered as Per Standard of Care to Reverse Rocuronium-Induced Neuromuscular Blockade in Adults Undergoing Elective Open Abdominal Procedure (19.4.334) (P05774) Completed
  25. Phase 3 Rocuronium Plus Sugammadex Versus Succinylcholine Alone in Participants Undergoing Short Surgical Procedures (19.4.319)(P05700 AM2)(COMPLETED) Completed
  26. Phase 3 Comparison of Sugammadex With Neostigmine During Laparoscopic Cholecystectomy or Appendectomy (P05699) Completed
  27. Phase 2 Neuromuscular Blockade for Post-Cardiac Arrest Care Completed
  28. Phase 2 A Bridging Trial Comparing Sugammadex (Org 25969) at Reappearance of T2 in Japanese and Caucasian Participants. Part B: Caucasian Participants (P05971) Completed
  29. N/A Neuromuscular Blocking Agents in the Elderly Completed
  30. N/A Optimal Inspiratory Pressure for Facemask Pressure-controlled Ventilation in Children Completed
  31. N/A Optimal Dose of Succinylcholine and Rocuronium for Electroconvulsive Therapy (ECT) Completed
  32. N/A Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies Completed
  33. N/A Use of Neuromuscular Blocking Agents and Neuromuscular Monitoring in 7 Danish Teaching Hospitals Completed
  34. N/A Desflurane Versus Propofol in the Sitting Position Completed
  35. N/A Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade. Completed
  36. N/A The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy Completed

Showing the 42 most-cited and recently-updated of 42 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
General anesthesia with reduced rocuronium and sugammadex reversal safely enabled cesarean section in a patient with inclusion body myositis
Anesthesiology & Pain Medicine Sys. Review
General anesthesia with reduced rocuronium and sugammadex reversal safely enabled cesarean section in a patient with inclusion body myositis A single case shows safe anesthesia for a pregnant patient with inclusion body myositis
This case report describes the perioperative anesthetic management of a 43-year-old pregnant patient with inclusion body myositis undergoing…
A 43-year-old pregnant patient with inclusion body myositis had a cesarean section without complications. Her baby scored 10 out of 10 on Ap…
Frontiers Jun 2, 2026