Semaglutide and liraglutide are associated with the greatest weight reductions in patients with schizophrenia
New data shows weight loss options for people with schizophrenia
This network meta-analysis of 5898 patients with schizophrenia spectrum disorders evaluated pharmacological interventions for weight reducti…
New data identifies specific medications that help people with schizophrenia manage weight gain while staying on their standard antipsychoti…
Phase 2 Trial Evaluating Zalfermin and Semaglutide Combinations for Metabolic Dysfunction Associated Steatohepatitis
Trial Shows Semaglutide May Impact Liver Fibrosis in MASLD
A 52-week trial assessed whether zalfermin combined with semaglutide improves liver fibrosis in patients with advanced steatohepatitis.
A new trial suggests semaglutide may improve liver fibrosis in patients with MASLD, while other combinations did not show significant result…
Rapid weight regain occurs after discontinuation of semaglutide or tirzepatide
Weight returns quickly after stopping semaglutide or tirzepatide medications
This meta-analysis of 1,776 participants who discontinued semaglutide or tirzepatide found rapid weight regain following treatment cessation…
People who stop taking semaglutide or tirzepatide often see rapid weight regain, highlighting the need for careful planning when ending trea…
GLP-1 Receptor Agonists Reduce Mortality and Hospitalization in Heart Failure with Preserved Ejection Fraction
GLP-1 medications show potential to reduce heart failure hospitalizations
Meta-analysis data suggests semaglutide and tirzepatide significantly lower composite mortality and hospitalization rates in HFpEF patients.
New analysis suggests GLP-1 medications like semaglutide and tirzepatide may lower the risk of death and hospital stays for those with heart…
Tirzepatide shows a mean difference of 4.23% weight loss over semaglutide at 6 months
Incretin drugs may help patients after bariatric surgery
This meta-analysis evaluates incretin receptor agonists for patients with suboptimal outcomes following metabolic bariatric surgery. The ana…
New data shows that specific medications can help people who need extra weight loss support after having weight loss surgery.
Pharmacist-led medication therapy management improves adherence and glycemic control in a patient with complex T2DM
Pharmacist-led care improves blood sugar for woman with long-term diabetes
This case report describes a single patient with type 2 diabetes who received pharmacist-led medication therapy management. The intervention…
A pharmacist-led review helped a woman with a 30-year history of Type 2 Diabetes significantly improve her medication adherence and blood su…
Tirzepatide reduces hypertension risk but increases hypotension risk compared to semaglutide in T2DM and obesity
Tirzepatide shows lower risk of high blood pressure than semaglutide
This meta-analysis of 47,332 patients with Type 2 Diabetes Mellitus or obesity compared tirzepatide and semaglutide regarding blood pressure…
New data compares how two popular weight and diabetes medications affect blood pressure, showing different risks for each treatment.
GLP-1 receptor agonists associated with favorable cardiovascular outcomes in adults with Type 2 Diabetes
GLP-1 medications show heart benefits for people with Type 2 Diabetes
This meta-analysis of randomized controlled trials included 97,173 adults with Type 2 diabetes to evaluate GLP-1-based therapies. The analys…
A large review of clinical trials shows that GLP-1 therapies can reduce major heart events and deaths in adults with Type 2 diabetes.
Efficacy and Safety Profile of Subcutaneous Semaglutide for Weight Management in Adults
Semaglutide helps people with obesity lose significant body weight
Semaglutide demonstrates significant weight reduction in patients with obesity, though clinicians must manage increased gastrointestinal sid…
A new review shows semaglutide leads to significant weight loss for adults with obesity, though it can cause common stomach issues.
Orlistat and semaglutide may improve ovulation and pregnancy rates in women with overweight or obesity
Weight loss medications may help women with obesity achieve pregnancy
This meta-analysis of 7 clinical trials involving 575 women found that orlistat increased ovulation and pregnancy rates compared to lifestyl…
New data suggests that certain weight-lowering drugs like orlistat and semaglutide could improve ovulation and pregnancy rates for women wit…
GLP-1 RA exposure in early pregnancy not significantly tied to hypertensive disorders
GLP-1 Medications Show No Link to Pregnancy Hypertension Risk
This meta-analysis of observational cohort studies assessed the risk of hypertensive disorders of pregnancy (HDP) after periconceptional or …
A large review of over 10,000 pregnancies suggests that GLP-1 medications may not increase the risk of high blood pressure during pregnancy.
Semaglutide improves MASH resolution (OR 3.48) and liver fat reduction in MASLD patients
Semaglutide helps resolve liver inflammation in patients with MASH
This meta-analysis of 1908 patients with MASLD and MASH found that semaglutide significantly improved MASH resolution (OR 3.48) and reduced …
New data shows semaglutide can reduce liver fat and inflammation for people with fatty liver disease, though results on scarring vary.