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Home › Medications › sertraline

sertraline

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials of sertraline

56 trials tracked of sertraline: 34 in phase 3 or 4 and 16 with published results. The most-cited published study has 153 citations.

56Trials tracked
34Phase 3 & 4
0Recruiting
16With published results
Phase distribution
Phase 4 18 Phase 3 16 Phase 2 11 Phase 1 2 Other / NA 9
  1. Phase 3 Treatments for Depression: Drug Versus Psychotherapy Completed · 153 cited
  2. Phase 3 Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis Completed · 127 cited
  3. Phase 3 Chronic Kidney Disease Antidepressant Sertraline Trial Completed · 122 cited
  4. Phase 3 Comparison of Two Treatments for Post-Traumatic Stress Disorder Completed · 121 cited
  5. Phase 3 Rhodiola Rosea Therapy of Major Depressive Disorder Completed · 109 cited
  6. Phase 4 Treatment of Diabetes and Depression in Hispanics and African Americans and Its Effect on A1c and Quality of Life. Completed · 97 cited
Show 44 more trials
  1. Phase 4 Evaluating the Effectiveness of Sertraline in Treating Women With Premenstrual Dysphoric Disorder Completed · 85 cited
  2. Phase 4 PROlonGed ExpoSure Sertraline Completed · 38 cited
  3. Phase 3 A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive Disorder Completed · 24 cited
  4. Phase 4 Stress & Premenstrual Symptoms Study Completed · 17 cited
  5. Phase 3 Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial) Completed · 13 cited
  6. Phase 4 A Pilot Trial of Perinatal Depression Treatment in HIV Infected Women Completed · 12 cited
  7. Phase 3 Brexpiprazole as Combination Therapy With Sertraline in Treatment of Adults With PTSD Completed · 12 cited
  8. Phase 4 Cost- Effectiveness and Quality of Life Assessment in Bipolar Disorder Depressive Episode Completed · 6 cited
  9. Phase 4 Cost- Effectiveness and Quality of Life Assessment in Major Depression Disorder Completed · 6 cited
  10. Phase 3 Brexpiprazole as Combination Therapy With Sertraline in the Treatment of Adults With Post-traumatic Stress Disorder Completed
  11. Phase 4 Frontal Hypoperfusion Effects on Antidepressant Outcomes in Late-Life Depression Completed
  12. Phase 4 Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems Completed
  13. Phase 4 Adding an Insulin-Sensitizing Medication to Depression Treatment for People Who Are Depressed and Overweight Completed
  14. Phase 4 A Study Comparing Duloxetine to Other Antidepressants in the Treatment of Severe Depression Completed
  15. Phase 4 A Study of Sertraline to Prevent PTSD Completed
  16. Phase 4 Sertraline Pharmacotherapy for Alcoholism Subtypes Completed
  17. Phase 4 Improving Treatment Outcomes in Pharmacotherapy of Generalized Social Anxiety Disorder Completed
  18. Phase 4 Treatments for Psychogenic Nonepileptic Seizures (NES) Completed
  19. Phase 4 Combined Mirtazapine and SSRI Treatment of PTSD: A Placebo-Controlled Trial Completed
  20. Phase 4 Antidepressant Treatment of Melancholia in Late Life Completed
  21. Phase 4 A Study Of Sertraline Compared With Paroxetine In The Treatment Of Panic Disorder Completed
  22. Phase 3 Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart Failure Completed
  23. Phase 3 Quetiapine XR Versus Sertraline in Acute Bipolar Depression as add-on Therapy Completed
  24. Phase 3 Study of Pharmacotherapy of Psychotic Depression Completed
  25. Phase 3 Treatment Strategy to Prevent Mood Disorders Following Traumatic Brain Injury Completed
  26. Phase 3 Ziprasidone vs. Sertraline/Haloperidol in Psychotic Depression Completed
  27. Phase 3 Therapies for Treatment-Resistant Panic Disorder Symptoms Completed
  28. Phase 3 Exercise to Treat Depression in Individuals With Coronary Heart Disease Completed
  29. Phase 2 A Trial of Sertraline in Young Children With Autism Spectrum Disorder Completed
  30. Phase 2 A Study of Flexible Dose Brexpiprazole as Monotherapy or Combination Therapy in the Treatment of Adults With Post-traumatic Stress Disorder (PTSD) Completed
  31. Phase 2 Geodon for the Treatment of Refractory Social Anxiety Disorder Completed
  32. Phase 2 Trial of Sertraline to Treat Children With Fragile X Syndrome Completed
  33. Phase 2 Effectiveness of Sertraline Alone and Interpersonal Psychotherapy Alone in Treating Women With Postpartum Depression Completed
  34. Phase 2 Effects of Sertraline on Brain Connectivity in Adolescents With OCD Completed
  35. Phase 2 Combined Treatment for Alcohol-Dependent Individuals With PTSD Completed
  36. Phase 2 The Serotonin Transporter Availability for Prognosing Major Depressive Disorder (MDD) Treatment and Detecting MDD Completed
  37. Phase 2 Treatment of Post-Traumatic Brain Injury (TBI) Depression Completed
  38. Phase 2 Establishing Moderators and Biosignatures of Antidepressant Response for Clinical Care for Depression Completed
  39. Phase 2 Clinical Efficacy of Sertraline Augmented With Gabapentin in Depressed, Recently Abstinent Cocaine-dependent Humans Completed
  40. Phase 1 A Study Comparing the Drug Exposure in Humans After Administration of a 50 mg Tablet of Sertraline Hydrochloride as Compared to a 50 mg Capsule of Sertraline Hydrochloride Under Fasted (Nonfed) Conditions Completed
  41. Phase 1 A Pharmacokinetic Study of the Coadministration of LY2216684 With Sertraline Completed
  42. N/A Special Investigation Of Long Term Use Of Sertraline. Completed
  43. N/A fMRI Study of Treatment Changes in Major Depression Completed
  44. N/A Magnetic Resonance Imaging Study of Geriatric Depression Completed

Showing the 50 most-cited and recently-updated of 56 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
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