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Psychiatry
Cohort
Deep learning model identifies neural connectivity patterns in patients with obsessive-compulsive disorder
AI model identifies brain connectivity patterns in OCD
Researchers utilized a transformer-based deep learning model to analyze brain connectivity in individuals with obsessive-compulsive disorder…
New deep learning technology can identify specific patterns of reduced brain connectivity linked to obsessive-compulsive disorder.
medRxiv
Apr 27, 2026
Psychiatry
Sys. Review
Narrative review proposes connectomic-guided psychosurgery framework for treatment-refractory patients
Researchers report framework for psychosurgery in treatment-refractory cases
This narrative critical review synthesizes contemporary psychosurgery options for treatment-refractory psychiatric disorders. It proposes a …
A new framework proposes connectomic-guided psychosurgery for treatment-refractory OCD, depression, and related disorders, based on symptom …
Frontiers
Apr 23, 2026
Psychiatry
Case-Control
WGS in multiplex OCD pedigrees identifies rare variants in NPY5R, DLGAP1, and MAPK8IP3
OCD Genes Found in Family Clusters
This case report performed whole genome sequencing in 25 individuals from two multiplex OCD pedigrees to identify rare protein-disrupting va…
Imagine a family where multiple members — parents, children, siblings — all struggle with obsessive thoughts and compulsive rituals.
medRxiv
Apr 22, 2026
Radiology & Imaging
Meta-analysis
Meta-analysis of connectome-based fMRI models shows high diagnostic accuracy in obsessive-compulsive disorder.
Brain Scan Pattern Can Spot OCD with High Accuracy
This meta-analysis evaluated connectome-based diagnostic models derived from resting-state fMRI in 563 individuals with obsessive-compulsive…
A new brain scan pattern can spot obsessive-compulsive disorder with high accuracy, offering a clear test for millions who currently struggl…
Apr 19, 2026
Psychiatry
Deep brain stimulation of the anterior limb of the internal capsule reduced OCD symptoms in a small observational study.
A Tiny Brain Signal May Show When OCD Treatment Is Working
This observational study evaluated deep brain stimulation (DBS) of the anterior limb of the internal capsule in 10 clinically responsive obs…
A drop in a specific brain wave signal may tell doctors when deep brain stimulation is finally easing severe obsessive-compulsive disorder s…
medRxiv
Apr 16, 2026