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Diabetes & Endocrinology
RCT
Real-time CGM improved HbA1c versus SMBG in adults with type 2 diabetes on basal insulin and modern therapies
Real-time glucose monitoring improves blood sugar control in type 2 diabetes
This randomised controlled trial compared real-time continuous glucose monitoring against standard self-monitoring of blood glucose in adult…
A new trial shows continuous glucose monitoring helps lower blood sugar levels better than standard finger-prick testing for adults with typ…
Jun 1, 2026
Diabetes & Endocrinology
Meta-analysis
SGLT2 and dual SGLT1/2 inhibitors reduce cardiovascular death or heart failure hospitalization risk in type 2 diabetes patients
Three diabetes drugs lower heart failure and heart attack risk
This network meta-analysis evaluates bexagliflozin, ertugliflozin, and sotagliflozin versus placebo for patients with type 2 diabetes. The a…
Three newer diabetes drugs cut heart failure and heart attack risk in people with type 2 diabetes, a new analysis finds.
Jun 1, 2026
Diabetes & Endocrinology
Meta-analysis
SGLT2 inhibitor use associated with increased diabetic ketoacidosis risk, especially with elevated HbA1c
New review shows SGLT2 drugs raise DKA risk when blood sugar is high
This meta-analysis of observational and randomized trials found SGLT2 inhibitor use is associated with an increased risk of diabetic ketoaci…
A big review of many studies found that medicines for diabetes called SGLT2 inhibitors can increase the chance of a serious condition called…
Jun 1, 2026
Diabetes & Endocrinology
Meta-analysis
Triple oral therapy with metformin, SGLT-2, and DPP-4 inhibitors lowers HbA1c better than dual regimens in adults with type 2 diabetes
Triple oral diabetes drugs lower blood sugar better than two-drug regimens
A systematic review and meta-analysis of 2,606 adults with type 2 diabetes found that triple oral therapy combining metformin, an SGLT-2 inh…
A large analysis shows that taking three specific oral diabetes medicines together lowers blood sugar more effectively than taking just two …
NEJM
May 30, 2026
Allergy & Immunology
Sys. Review
Narrative review examines metabolic syndrome and novel agents in kidney transplant recipients
Kidney transplant patients face high metabolic risks and rejection
This narrative review addresses antibody-mediated rejection and metabolic syndrome in kidney transplantation recipients. The authors note th…
About half of kidney transplant recipients develop metabolic problems within a year, while antibody-mediated rejection remains a major cause…
Frontiers
May 21, 2026
Drug Pipeline
Meta-analysis
Network meta-analysis of finerenone and SGLT2 inhibitors in heart failure with preserved or mildly reduced ejection fraction
New analysis shows finerenone and SGLT2 drugs help lower heart failure hospitalization risks for patients with preserved ejection fraction
This network meta-analysis evaluated finerenone, sodium–glucose cotransporter 2 inhibitors, renin–angiotensin system inhibitors, and angiote…
A large review of over 65,000 patients found that finerenone and SGLT2 inhibitors reduce hospital stays and worsening heart failure compared…
Frontiers
May 15, 2026
Cardiology
Meta-analysis
Meta-analysis finds SGLT2 inhibitors reduce cardiac arrest risk in CKD patients
SGLT2 Inhibitors Lower Cardiac Arrest Risk in Kidney Disease
This meta-analysis of 8 RCTs evaluated SGLT2 inhibitors versus placebo in patients with chronic kidney disease. SGLT2i significantly reduced…
A meta-analysis of 8 trials found SGLT2 inhibitors cut cardiac arrest risk by 47% in chronic kidney disease patients, though other arrhythmi…
Frontiers
May 13, 2026
Drug Pipeline
Meta-analysis
Combining finerenone with SGLT2 inhibitors lowers mortality and cardiovascular events in diabetic chronic kidney disease patients
A Two-Drug Combo May Save Lives in Diabetic Kidney Disease
A meta-analysis of 1,580 patients shows dual therapy with finerenone and SGLT2 inhibitors significantly reduces mortality and kidney events …
A new analysis finds that pairing finerenone with an SGLT2 inhibitor may significantly lower the risk of death and heart problems for people…
Frontiers
May 13, 2026
Diabetes & Endocrinology
Meta-analysis
Network meta-analysis compares bexagliflozin efficacy and safety with other SGLT2 inhibitors in type 2 diabetes
New analysis shows bexagliflozin helps lower blood sugar and weight in adults with type 2 diabetes compared to other drugs
This systematic review and network meta-analysis synthesized evidence on bexagliflozin versus other SGLT2 inhibitors and placebo in adults w…
A large review of 26,838 patients found bexagliflozin lowers blood sugar and weight well. It also lowers blood pressure and causes fewer inf…
Frontiers
May 13, 2026
Diabetes & Endocrinology
Meta-analysis
Meta-analysis shows SGLT2 inhibitors reduce all-cause mortality in heart failure patients
Heart Drug Cuts Death Risk by 14% in Heart Failure Patients
This meta-analysis evaluated SGLT2 inhibitor therapy in patients with heart failure, irrespective of ejection fraction or diabetes status. T…
A heart failure drug originally made for diabetes now shows it can cut death risk by 14% and keep people out of the hospital, and it works f…
Frontiers
May 13, 2026
Cardiology
Meta-analysis
SGLT-2 inhibitors reduce heart failure hospitalization and stroke in patients with acute coronary syndrome
SGLT-2 Drugs Cut Stroke Risk After Heart Attack
This meta-analysis evaluated SGLT-2 inhibitors in patients hospitalized for acute coronary syndrome with additional risk factors. The analys…
New research shows that a specific diabetes drug can lower the risk of stroke and heart failure in people recovering from a heart attack.
May 8, 2026
Cardiology
Meta-analysis
Network meta-analysis compares glucose-lowering therapies for heart failure with reduced ejection fraction and type 2 diabetes
Sotagliflozin Cuts Heart Failure Risk By Half In High-Risk Patients
This systematic review and network meta-analysis synthesized evidence on three glucose-lowering therapies for patients with coexisting heart…
New drugs for diabetes could also save lives in people with heart failure and lower the need for hospital visits.
Frontiers
May 8, 2026