Phase 3 N=2,108 Regional Anesthesia and Breast Cancer Recurrence
Breast Neoplasms
Primary: Number of Participants Who Had Breast Cancer Recurrence After Breast Cancer Surgery — 111; 102 participants — p=0.84
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=60 Epidural Anesthesia for Transurethral Resection of The Prostate
Epidural Catheter · Epidural Analgesia · Geriatric Cardiology
Primary: Time to Reach Sensory Block at T10 — 15.25; 10.50; 11.25 Minutes — p=0.05
N/A N=140 Dural Puncture Epidural Versus Epidural Anesthesia for Cesarean Delivery
Pain Levels
Primary: Onset Time of Surgical Anesthesia — 422; 655 seconds
Phase 3 N=45 Bupivacaine With Epidural Volume Extension
Spinal Anesthesia · Epidural; Anesthesia
Primary: Time Until PACU Discharge in Minutes — 135; 50 minutes
Phase 3 N=104 Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery
Intraoperative Complication · Malignant Female Reproductive System Neoplasm · Pain
Primary: Relative Pain Scores, as Measured by the Pain Numeric Rating Scale (NRS) — 3.87; 4.95 score on a scale
N/A N=116 Perioperative Intravenous Lidocaine or Epidural Anesthesia on Outcomes in Complex Spine Surgery
Spine Surgery
Primary: Mean Pain Scores — 4.4; 5.3 verbal response scores — p=<0.001
Early Phase 1 N=70 Comparison of Chloroprocaine vs Lidocaine for Epidural Anesthesia in Cesarean Delivery
Surgical Anesthesia, Cesarean Section
Primary: The Onset Time to Surgical Anesthesia — 558; 655 seconds — p=0.10
Phase 2 N=66 The Prevention of Hypotension After Epidural Analgesia After Major Surgery
Hypotension · Pain
Primary: Changes Between the 3 Groups Assessed by Blood Pressure Measurement — 5; 2; 3; 10 Participants — p=0.165
N/A N=364 Effectiveness of Epidural Anesthesia for Thoracic and Abdominal Surgery
Analgesia Disorder · Anesthetic Complication Epidural · Adverse Reaction to Epidural Anesthesia
Primary: Number of Patients Reporting Postoperative Verbal Rating Scale Pain at Rest More Than 7 — 89 Participants
N/A N=100 Fluoroscopy-guided Versus Traditional Placement of Epidural Catheters
Pain, Postoperative · Pain, Chronic
Primary: Intravenous Pain Medication — 63; 66 milligrams
N/A N=30 Anesthesia During Neurophysiologic Monitoring in Scoliosis Patients
Idiopathic Scoliosis
Primary: Amplitude Required to Elicit the MEP — 307; 417 milliamperes
N/A N=61 CSE v. Epidural for Postpartum Depression
Depression, Postpartum · Labor Pain
Primary: Edinburgh Postnatal Depression Score (EPDS) — 4.23; 4.71 score on a scale — p=0.7463
Phase 4 N=20 Awake Caudal Catheter vs General Anesthesia
Inguinal Hernia
Primary: Number of Participants With Return to Baseline Respiratory Function. — 11; 9 Participants
Phase 3 N=75 Comparing Bupivacaine, Lidocaine, and a Combination of Bupivacaine and Lidocaine for Labor Epidural Activation
Labor Pain
Primary: Time to Achieve an Adequate Epidural Level for Labor Analgesia — 7.0; 11.0; 8.5 minutes
Phase 4 N=35 Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment
Endodontic Disease · Post Operative Pain · Symptomatic Irreversible Pulpitis
Primary: Post-operative Pain Level 6 Hours on a Visual Analog Scale — 64.2; 43.1 units on a scale
Phase 4 N=84 Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery
Pain
Primary: Pain Score on Movement (Sitting in Bed From a Supine Position) — 5; 5 score on a scale
Phase 4 N=80 Effects of Epidural Local Anesthetics on Propofol Induction
General Anesthesia · Propofol Target-controlled Infusion · Thoracic Epidural Anesthesia
Primary: Propofol Effect-site Concentration — 1.76; 1.14; 1.09; 1.04 ug/ml
N/A N=100 Patient Education on Labor Analgesia Options
Labor Analgesia
Primary: Survey to Determine Utility and Effect of Educational Materials — 79; 21; 93; 7 percentage of patients responding — p=<0.0001
Phase 4 N=159 3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty
Osteoarthritis, Hip
Primary: Percentage Ambulating Early After Spinal Anesthesia — 9; 20; 35 Participants
N/A N=76 Local Anesthesia and Pain Perception During an Amniocentesis
Pregnancy
Primary: Intensity of Perceived Maternal Pain as Measured by the Visual Analogue Scale (VAS) — 9.5; 18.4 units on a scale
N/A N=90 Analgesia After Total Hip Arthroplasty: Peri-Articular Injection Versus Epidural Patient Controlled Analgesia (PCA)
Osteoarthritis
Primary: Time Until Patient is Ready for Discharge — 2.4; 2.3 days
Phase 4 N=43 Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal)
Adverse Reaction to Spinal Anesthetic · Maternal Care for Cervical Incompetence
Primary: Time to Resolution of Motor Block — 109; 112 minutes
N/A N=84 Decreasing Postoperative Pain Following Endometrial Ablation
Postoperative Pain
Primary: Postoperative Pain Score — 2.71; 1.44; 3.37; 2.81 units on a scale
Phase 4 N=101 Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain
Labor Pain
Primary: Number of Subjects With Success Rate at 15 Minutes Post-epidural Bolus Injection — 31; 38 Participants — p=0.38
Phase 4 N=179 Comparison of PIEB vs CEI for Labor Analgesia
Labor Pain
Primary: Volume of Local Anesthetic Received Through Patient Controlled Epidural Analgesia (PCEA) Per Hour — 4.03; 4.52 milliliters per hour — p=0.17
Phase 4 N=120 Programmed Intermittent Bolus Dosing Versus Continuous Epidural Infusion for Epidural Analgesia in Abdominal Surgery.
Pain, Acute
Primary: Total Local Anesthetic Utilized in First 24 Hours — 126; 123 mg — p=0.74
N/A N=104 Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Termination of Pregnancy Analgesia
Medical; Abortion, Fetus
Primary: Incidence of Motor Block — 24; 3 participants — p=< 0.001
Phase 1 N=200 Epidural Neostigmine for Labor Pain
Labor Pain
Primary: Amount of Drug Consumed Per Hour in Each Group(Arm) — 16.2; 14.6; 15.3; 16 milliliters per hour
Phase 4 N=68 Does the Addition of Epinephrine Prolong the Duration of Spinal Anesthesia for Repeat Cesarean Section?
Spinal Anesthesia · Cesarean Section
Primary: Sensory Recovery — 135; 165; 120 minutes
Phase 4 N=602 Prophylactic Ephedrine and Combined Spinal Epidurals for Labor
Labor Pain
Primary: Early Profound Fetal Bradycardia — 8; 14 participants — p=0.18