Clinical Trial Search

Primary: Change From Baseline in Root Canal Bleeding Score — 2.33; 0.13 score on a scale — p=<.0001

Primary: Change From Baseline in Root Canal Bleeding — 3.40; 3.73; 0.26; 3.03 millimeters — p=<.0001

Primary: Number of Colony Forming Units Per Millilitre — 80300000; 79900000; 74000000; 73000000 CFU/ml

Primary: Bacterial Levels — 4290; 10800 DNA copies — p=0.04

Primary: Metabolic Activity of Persistent Bacteria — 4.748; 2.57; 2.614; 4.0008 RNA/DNA ratio

Primary: Visual Analogue Scale (VAS) — 4.06; 2.68; 2.41; 2.27 score on a scale

Primary: Post-operative Diameter of the Periapical Lesion — 2.07; 0.98; 1.12; 0.78 Post-operative lesion diameter- mm2

Primary: The Primary Outcome Parameter Will be the Difference in Bacterial Reduction Between the Experimental and Control Disinfection Groups Group (Ferumoxytol) and Comparison…

Primary: Percent of Patients With Success as Defined by no or Mild Pain as Analyzed on a VAS Scale and no Narcotic Use — 52; 43 percentage of participants

Primary: Percent Reduction in Apical Radio-lucency — 17.4; 27.1 % Change in Diameter (mm)

Primary: Changes Between Initial and Post Treatment Dimensions of Periapical Lesions — 37.34; 34.04; 16.20; 17.54 square millimeters — p=<0.01

Primary: Number of Participants With Successful Injection Technique Assessed by Verbal Rating Scale (VRS) — 16; 37; 29; 26 Participants

Primary: Success Rate of the Implants and Prostheses (Participants). — 100; 100 percentage of participants — p=<0.05

Primary: 2D Radiographic Healing at 12 Months Follow up (Overall Cases) — 24; 29; 1; 1 osteotomy site

Primary: Comparison of MTA/FS Pulpotomy Versus RCT Treated Incisors With Acceptable Radiographic Outcome at 12 Months Post-procedure. — .97; .92 Proportion of incisors — p=.15

Primary: Change in Total Bacterial Load on the Exposed Implant Surface — 2.77; 4.21 log (colony forming units/ml)

Primary: Culture Positivity — 14; 13; 63; 63 Participants

Primary: Number of Participants With a PAI Score of < 3, = 3, or = 4 or 5 — 51; 3; 0 Participants

Primary: Clinical Success at 6 Months — 27; 30 Participants

Primary: Vitality of Teeth (Units) Using Thermal and Percussion Sensitivity Trend Observed During Study Duration (3-11 Months) — .559; .592; .065; .040 Teeth

Primary: Percentage Change in Lesion Volume at 12-months Follow-up — 80.429; 85.429; 86.929; 74.571 percent change — p=<0.05

Primary: Percent Bacteria Biofilm — 32.78; 20.14; 11.8; 74.03 percentage of disc covered

Primary: Pain Intensity Measure: Visual Analogue Pain Scale — 11.8; 8.8; 9.4; 10.3 score on a scale — p=0.329

Primary: Pain as Assessed by the Visual Analog Scale — 0; .33 score on a scale

Primary: Clinical Postoperative Pain — 30.5; 20.6 score on a scale

Primary: Healing Evaluation Using Inflammatory-Proliferative-Remodelling Scale (IPR Scale): Inflammatory Phase — 2; 2.49 score on a scale

Primary: Survival of Dental Prosthesis — 19; 14; 17 Teeth

Primary: Plaque Index — 0.5; 0.7; 0.7; 0.8 Plaque Index (PI)

Primary: Frequency of Blood Dendritic Cells From Baseline — 12; 14 % MFI

Primary: Effect of Trypsin-Chymotrypsin on Post-operative Pain After Single Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis — 3.47; 3.53; 2.93; 6.13 score on…