N/A N=19 Modulation of Motor Cortex Excitability by TMS and tDCS (MAGS1)
Motor Activity · Motor Neuroplasticity
Primary: Changes in Motor-evoked Potentials Ratios — 1.32; 0.73; 1.03 Ratio (unit: uV)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=41 Modulating Human Cortical Plasticity With Transcranial Electrical Stimulation
Healthy · Schizophrenia
Primary: Change in Amplitude of N100 Component of the Auditory Evoked Potential — -1.1; -0.35; -0.77; -0.33 microvolts
N/A N=26 Motor Cortex Plasticity and the Effect of Deep Intramuscular Needling Stimulation Therapy (DIMST) in Osteoarthritis Pain
Knee Osteoarthritis · Chronic Pain
Primary: Pain Pressure Threshold (PPT) After Intervention.. — 8.82; 6.66 Kgf / cm2
N/A N=30 Effect of Aging on Cortical Excitability and Motor Learning
Aging
Primary: Magnetic Resonance Spectroscopy — 0.41; -0.29 ppm — p=0.05
N/A N=64 Cortical Contributions to Motor Sequence Learning
Brain Injuries
Primary: Serial Reaction Time Task (SRTT) Performance — 31; 35; 38; 24 milliseconds (ms)
N/A N=13 Metaplasticity Experimental Design and Comparison of Motor Outcome Measure Sensitivity to Change
Healthy
Primary: Percent Change in MEP Amplitude — 1.19; 1.06; 1.38 Percent Change
N/A N=30 Anesthesia and Motor Evoked Potential (MEP) Recruitment
Idiopathic Scoliosis
Primary: Effect of Pulse Train Length on Transcranial Motor Evoked Potentials (TcMEP) Area Under Total Intravenous Anesthesia (TIVA) and TIVA Plus 3% Desflurane — 2 Participants
N/A N=40 Probing Cortical Excitability and Cognitive Function With TMS
Cognitive Dysfunction
Primary: Cortical Excitability: Resting Motor Threshold (RMT). — 51.1; 51.8 % of Max Stimulation Output (MSO)
N/A N=12 Noninvasive VNS to Facilitate Excitability in Motor Cortex
Stroke · Stroke Sequelae · Motor Activity
Primary: Safety of Combined taVNS and TMS — 0 Participants
N/A N=20 Direct Measurement of Motor Cortical Responses to tDCS
Parkinson Disease
Primary: Change in Primary Motor Cortex Beta-Band Spectral Power During Movement Preparation With Anodal tDCS — 12 log10(µV²/Hz)
N/A N=133 Modulation of Spontaneous Cortical Activity by tDCS: BRAIN Initiative I
Brain Function
Primary: Behavioral Performance (Accuracy) on Cognitive Tests of Perceptual Processing — 97; 98; 98 percent correct
N/A N=25 Measuring Plasticity in SFC/dACC Following Theta-Burst-Stimulation Using TMS
Cognitive Control
Primary: Post vs. Pre Change in Mid-frontal Theta Oscillations for iTBS vs. cTBS Stimulation — -0.043; 0.017 microVolts (uV) at FCz EEG electrode
N/A N=18 Transcranial Magnetic Stimulation Used to Both Measure Cortical Excitability and Explore Methamphetamine Cue Craving
Methamphetamine Dependence
Primary: Cue Craving Rating — 9.36; 7.92 scores on a scale
N/A N=8 Mechanisms of Non-Invasive Neuromodulation Interventions: Influence on Human Neurochemistry and Functional Connectivity
Non-invasive Neuromodulation in Healthy Subjects
Primary: Percent Change of GABA Concentration in a Voxel Encompassing the Left Motor Cortex, Measured at 30 Min After rTMS — 8; -27 percent change
N/A N=2 Presurgical Motor Mapping With Transcranial Magnetic Stimulation (TMS)
Epilepsy
Primary: Average Distance Between Positive Motor Mapping Sites of DCS
N/A N=39 Theta Connectivity in Working Memory
Executive Function
Primary: Number of Remembered Items — 1.72; 1.68; 1.68; 1.65 remembered items — p=0.783
N/A N=60 ADHD Electrophysiological Subtypes and Implications in Transcranial Direct-current Stimulation
ADHD · ADD
Primary: Clinical Assessment (Amen Questionnaire) — 9.85; 3.55; 5.15; 3.54 units on a scale
N/A N=4 Finding an Optimal Latency for Paired Associative Stimulation in People With Chronic Stroke
Stroke
Primary: Change in Cortical Excitability Using Single TMS Pulses — -.07667; 0.11; -.05667; .1233 Log10(microvolts)
N/A N=21 Targeting Personalized Brain States Reflecting Strong and Weak Corticospinal Tract Output in Real-time
Neurotypical Adults
Primary: Motor-evoked Potential (MEP) Amplitudes — 1.13; 0.96; 0.90 arbitrary units (normalized microvolts)
Phase 1 N=23 Spinal Excitation to Enhance Mobility
Aging
Primary: Walking Speed Change From Baseline — .054; .078; .085; .039 meters/second
N/A N=22 Structurally Reorganizing Motor Cortex in Stroke Patients Through Hebbian-type Stimulation
Stroke
Primary: Primary Motor Cortex (M1) Excitability Derived From Stimulus Response Curve — 4.68; 9.09; 5.01; 8.04 millivolts
N/A N=39 cTBS/fMRI Study of Hierarchical Control in the PFC
Transcranial Magnetic Stimulation
Primary: PFC-PPC Effective Connectivity — 0.3646; 0.3756; 0.3425; 0.4519 Hertz — p=0.5736
N/A N=20 Single-session tDCS in Cerebral Palsy
Cerebral Palsy · Perinatal Stroke · Periventricular Leukomalacia
Primary: Change in Motor Evoked Potential Amplitude — 12.4; 81.7; -34.4 percent change
N/A N=20 Electrophysiologic Studies of Cognition in Epilepsy Patients
Drug-resistant Epilepsy
Primary: Heartbeat Evoked Potential (HEP) for Attention — -1.5 µV
N/A N=92 Neuroproprioceptive "Facilitation, Inhibition" and Brain Plasticity
Multiple Sclerosis
Primary: White Matter Integrity — 0.5023; 0.5168; 0.4747 score on a scale
Phase 1 N=4 Improving Rehabilitation by Magnetic Brain Stimulation
Stroke
Primary: Percentage BOLD (Blood-oxygen-level Dependent Contrast Imaging) Signal From Baseline at 2 Weeks — 3; 2 percentage change of BOLD
N/A N=25 Metabolic Changes in the Activated Human Visual Cortex During Mild Hypoxia
Brain Hypoxia
Primary: Change in Glutamate Concentration During a Visual Stimulus Measured by fMRS at Normoxia — 4 percentage of concentration (micromol/g)
N/A N=11 Effect of Prolonged Electrical Stimulation on Neural Plasticity in Spinal Cord Injury
Spinal Cord Injury
Primary: Conduct pre-and Post-training Assessments of Behavioral Outcomes Using Wolf Motor Function Test and Jebsen Taylor Hand Function Test to Measure Upper Extremity Function…
N/A N=15 Fatiguing Arm Exercise Following Stroke
Stroke
Primary: Short Intracortical Inhibition (SICI) — 0.83; 1.14; 0.89; 0.88 SICI ratio — p=0.15
N/A N=58 Maximizing the Impact of Neuroplasticity Using Transcranial Electrical Stimulation Study 1
Transcranial Direct Current Stimulation · Healthy
Primary: Changes in Thalamocortical Functional Connectivity (FC) — 22.7; 20.5; 21.9 arbitrary units