N/A N=418 Targeted Infection Control in Long-term Care
Infection
Primary: Total Number of MDRO (Multidrug Resistant Organisms) Isolated — 1299; 1732 Total Number of MDRO isolates — p=<0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=33 Enhanced, Personalized and Integrated Care for Infection Management at the Point-Of-Care
Antibiotic Resistant Infection · Infection
Primary: Percentage of Appropriate Antimicrobial Prescriptions Recommended — 90 percentage of prescriptions appropriate
N/A N=190 Enhanced Room Cleaning in Intensive Care Units to Reduce Gown and Glove Contamination With Multi-drug-resistant Bacteria
Infection Control
Primary: Contamination of Disposable Isolation Gown and Gloves With Methicillin-resistant Staphylococcus Aureus or Multi-drug-resistant Acinetobacter Baumannii — 20.5; 17.2…
N/A N=3,256 Hand Hygiene and Hospital Acquired Infections
Complication of Surgical Procedure
Primary: Number of Participants With Postoperative Healthcare Acquired Infections — 108; 116 Participants
N/A N=325 Preventing the Spread of Infection in Nursing Homes
Staphylococcus Aureus
Primary: Rates of Staphylococcus Aureus Acquisition: Percentage of Short Stay Participants Who Acquired MRSA or MSSA (or Both) During the Study Period — 17; 8 Participants
N/A N=1,687 Hospital Design and Risk of Nosocomial Infections: A Prospective Controlled Trial
Vancomycin Resistant Enterococci Infection · Clostridium Difficile Infection · Nosocomial Infection
Primary: Incidence Density of Hospital-acquired Infection With Clostridium Difficile (CDI), and Hospital-acquired Infection or Colonization With Vancomycin-resistant Enterococcus…
N/A N=350 Trial of 2% Chlorhexidine Bathing on Nosocomial Infections in the Surgical Intensive Care Unit
Cross Infection · Pneumonia, Ventilator-associated · Catheter-related Infections
Primary: Incidence of Nosocomial Infection — 15; 30 participants — p=0.049
N/A N=200 Gown and Glove Use to Prevent the Spread of Infection in VA Community Living Centers
Methicillin-Resistant Staphylococcus Aureus
Primary: MRSA Transmission — 0.20; 0.02; 0.11; 0.01 Proportion of swabs positive for MRSA
Phase 3 N=2,518 Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit
Nosocomial Infections
Primary: Bacteremia — 3.52; 4.93 events per 1000 at-risk days
N/A N=149 Hub Cleansing to Prevent Hub Infection
Bacteremia
Primary: Number of Central Venous Catheter Hubs With Internal Contamination — 42; 18; 39; 14 contaminated hubs
N/A N=165 Passive Disinfection Cap Compliance Study
Infection, Hospital
Primary: Disinfecting Barrier Cap Compliance — 98.43 percentage of connector with compliance
N/A N=136 COVID-19 Project ECHO in Nursing Homes
Covid19
Primary: Infection Rate — 141.91; 106.57; 1.54; 2.86 infections per 1,000 residents in 4 week
N/A N=594 Reduction in IV Associated Contamination
Post-operative Infections
Primary: Presence of Bacterial IV Stopcock Lumen Contamination — 41; 32 percent stopcock contamination rate
N/A N=25,732 Pulsed UV Xenon Disinfection to Prevent Resistant Healthcare Associated Infection
Healthcare Associated Infection · Clostridium Difficile Infection · Infection Due to Multidrug Resistant Bacteria
Primary: Number of Environmentally-implicated Healthcare-Associated Infections (eiHAIs) Associated With the Additional Use of a PX-UV Disinfection Compared to Standard Terminal…
Phase 2 N=99 Reducing Urinary Tract Infection Rates Using a Controlled Aseptic Protocol for Catheter Insertion
Urinary Tract Infections · Catheter Infection · Catheter-Related Infections
Primary: Number of Participants With a Catheter Associated Urinary Tract Infection (CAUTI) — 7; 6 Participants
Phase 4 N=13,952 Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization
Hospitalization · Infection
Primary: Hospital Transfers Due to Infection — 1243; 1780 Transfers — p=<0.001
N/A N=339,902 Active Bathing to Eliminate Infection (ABATE Infection) Trial
Healthcare Associated Infections · Methicillin Resistant Staphylococcus Aureus · Multi Drug Resistant Organisms
Primary: MRSA and VRE Clinical Cultures — 0.87; 0.79 Hazard Ratio (Intervention vs Baseline) — p=0.17
N/A N=109 Bacterial Contamination of Healthcare Worker Uniforms
Bacterial Contamination of Healthcare Worker Uniforms
Primary: Total Bacterial Contamination of Healthcare Worker Uniform With Antimicrobial Properties Compared to Standard Healthcare Worker Uniform After an 8-hour Workday. — 41…
N/A N=4,210 A Cluster-randomized Cross-over Trial Evaluating the Comparative Effectiveness of Three Skin Antiseptic Interventions
Bacteremia
Primary: Blood Culture Contamination — 41; 32; 25 blood culture sets
N/A N=60 Safe Critical Care: Testing Improvement Strategies
Central Line-associated Bloodstream Infection (CLABSI) · Ventilator Associated Pneumonia
Primary: CLABSI and VAP Rates — 1.84; 2.42; 2.24; 2.47 events/1000 device days — p=<.05
Phase 4 N=112 Evaluation of Two Hand Hygiene Products in ICUs
Hand Hygiene Effectiveness
Primary: Bacterial Colony Forming Units Present on Hand Prints After Time Spent in Common Areas — 2.17; 1.81 log(10) transformed CFU
N/A N=58 Building an Optimal Hand Hygiene Bundle
Hand Hygiene · Health Care Associated Infection · Compliance
Primary: Hand Hygiene Compliance — -0.4; 1.8; -1.3; -3.7 percentage of change in HH compliance
N/A N=403 Antimicrobial Stewardship Program for Clostridium Difficile Infection.
Clostridium Difficile · Enterocolitis, Pseudomembranous
Primary: Number of Participants With Clostridium Difficile Infection Recurrence. — 34; 21 Participants — p=0.56
N/A N=16 Community Central Line Infection Prevention Trial
Infection
Primary: Total Number of Central Line Associated Blood Stream Infections (CLABSI) — 113; 84; 123; 109 infections
N/A N=780 Effect of Expanding (Gloving) Barrier Precautions for Reducing Clostridium Difficile Acquisition (and Infection) in VA
Clostridium Difficile
Primary: C. Difficile Acquisition Rates — 13.2; 10.4 C. diff acquisition per patient days — p=0.611
N/A N=86 Cleancision IntRaoperative Contamination prEvention Study
Wound Contamination · Colorectal Surgery
Primary: Efficacy (Enteric Bacterial Contamination on the Exposed Surface of the CleanCision Sheath Compared to the Protected Incision Edge) — 33.3; 9.5 % of participants with…
N/A N=210 Effect of Bed Bathing Methods on VRE Colonization in ICU Patients
Vancomycin-Resistant Enterococcus
Primary: Vancomycin-Resistant Enterococcus (VRE) Colonization — 0; 0; 30; 33 participants with VRE colonization — p=0.671
N/A N=1,518 Cost-Effectiveness Study Comparing Chlorhexidine Bathing With Active Surveillance Cultures to Prevent Methicillin-resistant Staphylococcus Aureus & Other Hospital Infections
Staphylococcal Infections
Primary: Acquisition of Methicillin-resistant Staph Aureus (MRSA) Colonization or Infection — 9; 10 participants — p=>0.05
N/A N=48 Effectiveness of a Online Training Program With a Clinical Procedure Standardized in Units of Nursing (CPSUN)
Infection Control · Preventive Measures
Primary: Number of Contaminated Cultures in the Control and Experimental Group Before Intervention and After the Learning Obtained With the Online Training Platform. — 17; 15; 5…
N/A N=79 An Isolation Device to Contain Aerosol During Aerosol Generating Procedures in the Operating Room
Aerosol Containment · Aerosol Generating Procedure
Primary: Particle Count Measurements During Intubation — 4026; 411; 105; 392 particles/cm^3 — p=<0.001